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NIHR GOSH BRC spinout Orchard Therapeutics signs strategic agreement with GSK

13 Apr 2018, 1:10 p.m.

GSK and Orchard Therapeutics today announced a strategic agreement, under which GSK will transfer its portfolio of approved and investigational rare disease gene therapies to Orchard, securing the continued development of the programmes and access for pat

GOSH Battens disease research team

Novel therapy for Battens Disease available on the NHS

19 Sep 2019, 4:04 p.m.

Patients at Great Ormond Street Hospital (GOSH) and across England are set to receive treatment for the rare nervous system condition Battens Disease, following a deal between the NHS and manufacturer Biomarin. The drug, which is called cerliponase alfa o

Burosumab treatment for XLH Rickets_before and after

Precision medicine improves growth for children with a rare form of rickets

6 Jul 2018, 10:39 a.m.

A new, targeted drug has been shown to significantly improve growth and control of rickets in children with X-linked hypophosphataemic rickets (XLH), a serious condition affecting about 300 children in the UK.

Intensive Care Unit

Rapid DNA sequencing is saving the lives of critically ill children

27 Jul 2018, 9:29 a.m.

A new rapid sequencing technique has helped doctors at Great Ormond Street Hospital (GOSH) to quickly diagnose children in intensive care, enabling them to receive the best treatment and reducing the time they have to spend hospital.

Professor Thomas Voit at the GOSH Biomedical Research Centre showcase

Research successes highlighted at BRC showcase event

16 Apr 2019, 4:27 p.m.

Over 150 people came along to the National Institute for Health Research (NIHR) GOSH Biomedical Research Centre showcase last month to hear about our latest research highlights - from cutting edge CAR-T therapies for leukaemia, to Oculome genomic sequenci

Child in bed smiling

GOSH researchers join experts in warning of the detrimental impact of a no deal Brexit on rare diseases

11 Dec 2020, 4:24 p.m.

Experts have warned that a ‘no deal’ Brexit will result in the exclusion of the UK from the 24 European Reference Networks (ERNs) that were established to improve the care of patients bearing the lifelong burden of a rare disease, which require highly spe

Waseem Qasim

Leukaemia trial shows promise and complexity of genome-edited cell therapies

12 Dec 2020, 5:16 p.m.

A ‘one size fits all’ immune therapy developed at the UCL Great Ormond Street Institute of Child Health (ICH) could help to clear cancerous cells in children and adults who have exhausted all other treatment options for B-cell acute lymphoblastic leukaemi

A selection of images from the 2021 competition

A Moment of Discovery 2022

9 Nov 2022, 3 p.m.

The Research and Innovation Communications team at GOSH/the NIHR GOSH BRC invite you to enter our Research and Innovation Showcase: A Moment of Discovery.

A selection of images from the 2nd annual NIHR GOSH BRC competition

3rd Annual NIHR GOSH BRC Image Competition - A Moment of Discovery

1 Nov 2023, noon

The Research and Innovation Communications team at GOSH and the NIHR GOSH Biomedical Research invite you to enter our Research and Innovation Showcase: A Moment of Discovery.

48% increase in clinical research participants at GOSH

20 Jul 2018, 11:34 a.m.

The number of people taking part in research trials at Great Ormond Street Hospital (GOSH) has increased by 48 per cent, according to figures released this week by the National Institute for Health Research (NIHR).

EEG

Cannabidiol reduces seizures for children with complex epilepsies

14 Jun 2018, 8:49 p.m.

Cannabidiol, a drug derived from cannabis but with the psychoactive ingredients removed, has been shown to reduce seizures by around 40 % in children with a rare form of drug resistant epilepsy known as Lennox-Gastaut syndrome (LGS).

Mark Peters

Critical research in intensive care

5 Aug 2019, 9:36 a.m.

A UK-wide clinical trial looking at what is the best level of oxygen to aim for children who are on ventilation in intensive care is set to launch later this year.

Somers CRF - interactive wall

Drug for rare form of rickets now available on the NHS

11 Jan 2019, 10:19 a.m.

A new, targeted treatment for the rare form of rickets called X-Linked Hypophosphataemia (XLH) is now available to NHS patients from 8 January 2019, following an international clinical trial.

Paul Brogan and Despina Eleftheriou

European clinical trial for Kawasaki disease to be led by GOSH and ICH researchers

27 Jun 2019, 1:42 p.m.

Researchers at the UCL Great Ormond Street Institute of Child Health (ICH) and Great Ormond Street Hospital (GOSH) are to lead a new clinical trial for Kawasaki syndrome (KD-CAAP), a rare immune system condition that causes swelling of the blood vessels o

Lyn Chitty ultrasound scan

Genetic testing helps diagnose developmental disorders before birth

1 Feb 2019, 11:05 a.m.

Genetic sequencing improved the diagnosis of abnormalities detected in ultrasound scans of developing babies, in new research from Great Ormond Street Hospital (GOSH), the Wellcome Sanger Institute and Birmingham Women’s Hospital.

Alex Stewart and Emma Shkurka

GOSH Allied Health Professionals awarded PhD studentships from the NIHR

13 Feb 2019, 3:39 p.m.

Two allied health professionals (AHPs) at Great Ormond Street Hospital (GOSH) have been awarded prestigious Clinical Doctoral Fellowships from the National Institute for Health Research (NIHR).

Elaine Cloutman Green Healthcare scientist

GOSH and ICH to tackle antibiotic resistance in children

27 Jun 2019, 1:43 p.m.

A new initiative set to tackle the global threat of antibiotic resistance (also known as antimicrobial resistance or AMR) has been awarded £3.3 million in government funding.

Jasper de Boer

GOSH Charity and Sparks funding for child health research at ICH

28 Feb 2019, 2:11 p.m.

Four UCL Great Ormond Street Institute of Child Health researchers have been awarded research grants from Great Ormond Street Hospital Children’s Charity and Sparks, the children’s medical research charity as part of their annual National Call.

Head shot of Kate Oulton. She has a short brown bob with a bulky fringe. She wears a dark blue jumper with and orange block around the neckline and shoulders

GOSH nurse to be part of prestigious new research leadership programme

8 Feb 2019, 4:22 p.m.

GOSH nurse Dr Kate Oulton is to become part of a brand new nurse and midwife research leadership programme - the National Institute for Health Research’s (NIHR) 70@70 Research Leader programme.

Exploration Art Spacesuit

To infinity and beyond!

23 Nov 2018, 11:32 a.m.

Last week, GOSH patients were joined by former NASA Astronaut Nicole Scott and Tim Peake (by Skype) for an exciting art project that is travelling the world!

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