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A look into the future of children’s research

17 Aug 2018, 4:36 p.m.

A new film series, led by Great Ormond Street Hospital (GOSH), shines a spotlight on the bright future of children’s research, and highlights how pioneering clinical trials across the UK are helping develop new treatments for children with health conditio

Research Activity Trail at GOSH

Marking International Clinical Trials Day at GOSH

28 May 2018, 9:59 p.m.

Earlier this month patients and families at GOSH (Great Ormond Street Hospital) were given the chance to get hands-on with science at our Research Activity Trial and with special lessons in the hospital school.

Professor Faith Gibson

More mental health research needed for young people with cancer

20 Aug 2019, 10:26 a.m.

A survey of young people, their friends, family and healthcare professionals has identified the most urgent research priorities for young people with cancer.

Neural tube imaging - Gabriel Galea

New award for vital research into the causes of birth defects

20 Jul 2018, 3:06 p.m.

Dr Gabriel Galea has been awarded a Wellcome Trust Clinical Research Career Development Fellowship to continue important research into the molecules, genes and physical forces that control the formation of the neural tube in the developing embryo.

New funding to support pioneering thymus transplant research at GOSH

11 Jul 2018, 2:19 p.m.

Professors Graham Davies and Adrian Thrasher have been awarded funding from Great Ormond Street Hospital (GOSH) Charity to further develop a cutting-edge new treatment for children with the rare immunodeficiency condition complete DiGeorge syndrome (cDGS)

Somers CRF toys in play area

Novel therapy reduces disease progression in rare neurodegenerative condition

21 Jun 2018, 11:55 a.m.

A pioneering new treatment trialled at Great Ormond Street Hospital (GOSH) reduces disease progression by 80 per cent for patients with the rare neurological disorder CLN2.

Cardiac research team

Predicting sudden cardiac death risk in children

14 Aug 2019, 12:59 p.m.

GOSH researchers have developed the first ever tool to identify children at risk of sudden death from a rare heart condition called hypertrophic cardiomyopathy (HCM).

Uncovering how human embryos develop in major new research project

29 Jul 2019, 10:07 a.m.

A new research project aiming to understand the earliest stages of human development is set to launch, led by scientists at the UCL Great Ormond Street Institute for Child Health (ICH).

100,000 Genomes Project hits half way mark

21 Feb 2018, 4:02 p.m.

The pioneering 100,000 Genomes Project has reached the 50,000 genomes landmark. It’s a milestone that has only been made possible through the generous participation of tens of thousands of patients and their families, including 1,492 GOSH families.

Sterile GOSgene laboratory

Advances in the treatment of the severe immune disorder Wiskott-Aldrich syndrome

20 Nov 2017, 2:29 p.m.

Researchers at Great Ormond Street Hospital (GOSH) have made an important breakthrough in understanding how the immune system becomes disrupted in Wiskott-Aldrich syndrome (WAS), a genetic disorder where the patient’s immune cells begin attacking their ow

GOSH researcher Karin Straathof in the lab

Dr Karin Straathof receives Sparks Early Career Investigator Award

27 Mar 2018, 2:28 p.m.

Dr Karin Straathof has been awarded the prestigious Sparks Simon Newell Early Career Investigator award in recognition of her outstanding work focused on understanding and harnessing the power of the immune system in treatment of childhood cancer.

Owen Arthurs, researcher, GOSH, ICH

Dr Owen Arthurs awarded NIHR Career Development Fellowship

20 Oct 2017, 3:20 p.m.

Dr Owen Arthurs has been awarded a Career Development Fellowship (CDF) from the National Institute for Health Research (NIHR).

New tablet reduces symptoms for young people with multiple sclerosis

17 Jan 2018, 12:30 p.m.

A daily tablet has been shown to reduce the debilitating symptoms experienced by children with Multiple Sclerosis (MS) and cut the chance of relapse by 82%. There are currently no treatments specifically approved for adolescents with MS and this is the fi

Professor Jugnoo Rahi

Paediatric Ophthalmologist and Epidemiologist Professor Jugnoo Rahi appointed NIHR Senior Investigator

26 Feb 2018, 4:04 p.m.

Professor Jugnoo Rahi has been appointed as National Institute for Health Research (NIHR) Senior Investigator in the eleventh annual competition.

GOSH patient James

UK-wide consortium to transform treatment for children and young people with arthritis and uveitis

27 Mar 2018, 5 p.m.

Researchers from the UCL Great Ormond Street Institute of Child Health (ICH) and Great Ormond Street Hospital (GOSH) will lead a UK-wide effort to drive the development of new, targeted treatments for children and young people with juvenile idiopathic art

Sterile GOSgene laboratory

£1 million award to push forward regenerative medicine research

13 Dec 2018, 10:19 a.m.

Researchers at Great Ormond Street Hospital (GOSH) and the UCL Great Ormond Street Institute of Child Health (ICH) are to lead a new collaboration exploring how stem cells can be engineered to evade immune responses.

AI bodysuit trial launched to help treat Duchenne muscular dystrophy

1 Feb 2018, 11:57 a.m.

A new artificially intelligent bodysuit to help understand how mobility is affected in boys with Duchenne will be trialled in a collaboration between researchers at Great Ormond Street Hospital (GOSH) and Imperial College London.

Liquid handling robot

BRC researchers part of collaboration to improve efficiency of gene therapy products

26 Jul 2018, 3:56 p.m.

A new collaboration aiming to develop advanced technologies for manufacturing ex vivo gene therapy products has been established between researchers at UCL Great Ormond Street Institute of Child Health (ICH) and Plasticell, a developer of stem cell techno

Meredyth Wilkinson, one of the study's first authors

Cutting edge new method reveals novel cause of Juvenile dermatomyositis

25 Jun 2018, 10:18 a.m.

A new in-depth method has helped shed light on the key role of B cells, a type of immune cell, in the rare childhood condition Juvenile dermatomyositis (JDM).

medical devices workshop

Driving forward medical device development

2 Oct 2019, 4:57 p.m.

The NIHR GOSH BRC last month hosted an inaugural medical devices workshop, in partnership with the UCL Institute of Healthcare Engineering.

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