BRC news

BRC latest news

This displays the latest news items related to the Biomedical Research Centre.

BRC researchers develop a new rapid test for Alzheimer’s and Lewy Body Dementia

National Institute for Health Research (NIHR) Great Ormond Street Hospital (GOSH) BRC (Biomedical Research Centre) researchers, working in collaboration with the BRC at NIHR Queen Square Dementia and the Wolfson Biomarker Dementia consortium at Institute of Neurology (IoN), have developed a new test to diagnose different types of dementia, which they hope will allow for more reliable and accurate diagnosis of the neurodegenerative conditions of Lewy Body Dementia and Alzheimer’s disease.

Treatment of the central nervous system as well as the peripheral organs proves beneficial in severe cases of Spinal Muscular Atrophy (SMA)

A pre-clinical study investigating treatment options for a severe form of Spinal Muscular Atrophy (SMA) has demonstrated that optimal treatment of a morpholino antisense oligonucleotide drug is achieved when the drug reaches the central nervous system as well as the peripheral organs.

High throughput screening identifies the genetic cause underlying a rare disease in a large nationwide cohort

A collaborative study between ICH and the Turkish Pediatric Endocrinology Society has used high throughput DNA analysis to identify the genetic cause of primary adrenal insufficiency in more than 80% of affected children.

A new, genetic diagnostic service for ciliopathy disorders has been launched

In a collaboration between Great Ormond Street Hospital (GOSH) North-East Thames Regional Genetics and the UCL Institute of Child Health, a new genetic diagnostic service for ciliopathy disorders has been launched for service delivery to the NHS.

Research suggests need for long-term follow-up for patients with Kawasaki Disease

Kawasaki disease is a rare condition that causes blood vessels to become inflamed and swollen. It predominantly occurs in children under the age of five. If left untreated, it results in balloon-like swellings (aneurysms) in the coronary vessels of approximately 25% of cases. To date, the cause of this disease remains unknown.