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Alyssa on ‘cell day’ - the day she received the base-edited cell therapy. May 2022.

GOSH patient receives world-first treatment for her 'incurable' T-cell leukaemia

11 Dec 2022, 8 a.m.

In May 2022, Alyssa, 13 from Leicester, became the first reported patient in the world to receive base-edited T-cells at Great Ormond Street Hospital for Children (GOSH), in collaboration with the UCL Great Ormond Street Institute of Child Health (UCL GOS

A thumbnail featuring Lyn in a circle image, against a graphic of two blue circles.

Professor Lyn Chitty made a Dame in New Year's Honours

30 Dec 2022, 10:30 p.m.

Professor Lyn Chitty has been made a Dame in the 2023 New Year’s Honours List.

A group of children face away from the camera with their hands in the air, looking at a scientist in a white coat, in front of a presentation on a screen

NIHR GOSH BRC funding goes into ‘space’ to share brain research

18 Jan 2023, 9 a.m.

A theatre group funded by the NIHR GOSH Biomedical Research Centre has developed their successful children’s event into an interactive online film for schools and festivals

A red and blue irregular shape against a black background

Research uncovers potential for new treatments for childhood autoimmune condition

23 Jan 2023, 10:21 a.m.

Research teams at GOSH and UCL GOS ICH have uncovered key inflammation pathways involved in Juvenile Dermatomyositis (JDM).

Photo of James, a GOSH patient with DMD who took part in the trial at the hospital. He is smiling.

Combining expertise for more efficient clinical trials of the future

22 Jan 2023, 8 a.m.

A group of researchers and clinical scientists have combined their expertise to develop a new way to monitor the progression of movement disorders and increase the efficiency of clinical trials.

A network of blue and purple branching tubes on a black background. The image shows many layers providing a 3D effect. There are yellow dots throughout around the image.

Stunning images showcase life-changing research at GOSH

28 Feb 2023, 9 a.m.

A captivating 3D image that is helping researchers to uncover the secrets of childhood cancers is crowned the winner of our 2022/23 image competition ‘A moment of discovery’.

A woman smiling at the camera with curly ginger hair

Dr Polly Livermore is GOSH’s first nurse to receive post-doctoral fellowship

6 Feb 2023, 4:08 p.m.

Children's nurse and Clinical Matron Dr Polly Livermore awarded GOSH's first NIHR Advanced Clinical and Practitioner Academic Fellowship scheme (ACAF).

Hannah in a white t-shirt looks down a microscope in a busy lab

Mentoring young people at the start of their careers in science and medicine

11 Feb 2023, 8 a.m.

In August 2022, the UCL Great Ormond Street Institute of Child Health (UCL GOS ICH) opened its laboratory doors for three days to invite members of the GOSH Young Persons’ Advisory Group for research (YPAG) to shadow researcher Merry Wilkinson.

6 GOSH YPAG members stand on the steps of the UCL Great Ormond Street Institute of Child Health

How the GOSH Young Persons’ Advisory Group for research is helping to inspire the next generation of women in science

11 Feb 2023, 8 a.m.

Our GOSH Young Persons’ Advisory Group (YPAG) for research is a group of young people aged between 10 and 21 who work closely with researchers and clinicians across GOSH and the UCL GOS ICH to advise them on many aspects of their research.

A small girl, with blonde hair in pigtails and with a nasal tube, listens to two scientists talking about DNA

Marking Rare Disease Day 2023

7 Mar 2023, 11 a.m.

Rare Disease Day is a global event that aims to raise awareness and generate change for those living with rare diseases. At GOSH, many of our patients and families are part of the rare disease community and so this year we were delighted to mark the…

Sampler in a lab in the Zayed Centre for Research

Adeno-associated viruses implicated in disease in world-first

30 Mar 2023, 4 p.m.

A research team spanning GOSH and UCL has, for the first time, connected adeno-associated viruses with development of hepatitis in some children

Researchers sit around a coffee table, discussing and taking notes. A women in blue jeans and a green jumper, with square glasses speaks to the group

A return of the NIHR GOSH BRC academic training weekend

25 Apr 2023, 9 a.m.

The weekend is part of a programme of training opportunities that the NIHR GOSH BRC offers to the wider paediatric research community and aimed to support attendees as they transition to independent researchers.

A close up of a pippet and test tubes.

GOSH staff recognised in prestigious research prize

18 May 2023, noon

Four members of staff from GOSH and UCL GOS ICH have today been recognised by the Academy of Medical Sciences for their exceptional contributions to the advancement of biomedical and health science

Blue stem cells with purple dots growing with tree like branches.

How 3D ‘bio-printing’ can shape mini-organs

9 Jun 2023, 4 p.m.

Scientists have shown for the first time how 3D printing can be achieved inside ‘mini-organs’ growing in hydrogels - controlling their shape, activity, and even forcing tissue to grow into ‘moulds’.

Kiki Syrad, the new Director of Research and Innovation at GOSH. The photo is of a professional quality, with Kiki smiling warmly at the camera.

Director of Research and Innovation appointed

13 Jun 2023, 1:30 p.m.

Dr Kiki Syrad has been appointed Director of Research and Innovation for Great Ormond Street Hospital NHS Trust.

A young boy wears safety goggles, a white lab coat and very large blue protective gloves. He holds onto and looks down a mini-microscope while sat on a lime green chair.

Celebrating International Clinical Trials Day with our patients and families

21 Jun 2023, 11 a.m.

On 19 May we enjoyed welcoming patients, their families and GOSH staff, including GOSH nursery to the Lagoon to celebrate International Clinical Trials Day as well as the NIHR “Be Part of Research" campaign.

A young girl in a blue t-shirt is sitting down with her back to the camera, stretching sideways to shake the hand of a man in a white shirt who is bending down to meet her. She is smiling and so is he.

GOSH receives over £3.5m for research and innovation

28 Jun 2023, 11:31 a.m.

GOSH has been awarded over £3.5m by the NIHR for vital research and innovation equipment that will help to improve treatments for children

Four people stand in a line, smiling at the camera with their arms around each other. On the far left stands a nurse., Jan, wearing a blue uniform and black framed square glasses. She stands next to a Austin's Mum, Louise, who has a dark brown bob wearing jeans and a black jumper. Austin stands next to his mum, wearing a black hoodie and black trousers. Finally, Danielle, another nurse, stands on the far right with blonde hair in a ponytail and a blue nurses uniform

Unlocking the mystery of long-lasting cancer treatment

6 Jul 2023, 8 a.m.

Researchers from across GOSH, UCL GOS ICH and the Wellcome Sanger Institute have published new insights that explain why some children have a longer remission than others after having cutting-edge CAR T-cell therapy for leukaemia.

A close up photograph of multiple pippets and test tubes.

Global genomic collaboration improves lives and treatment for children with epilepsy

17 Aug 2023, 8 a.m.

An international research collaboration, including GOSH and our research partner UCL Institute of Child Health, has shown that a technique known as rapid genome sequencing can provide a diagnosis for 43 per cent of children with unexplained epilepsy.

A tree like structure made up of fluorescent blue, green and pink dots.

Steps forward in gene therapy for hearing loss linked to rare disease

29 Aug 2023, 3 p.m.

An international team led by researchers at GOSH, UCL and the NIHR GOSH BRC have developed in mice a gene therapy that significantly reduces the hearing loss associated with Norrie disease.