GOSH and UCL researchers receive funding to improve outcomes for children and young people with cancer
18 Mar 2021, 10 a.m.
Researchers at University College London and Great Ormond Street Hospital receive £1.7m of grants in new Cancer Research UK-Children with Cancer UK Innovation Awards.
MicroRNA from stem cells could be used to treat babies while still in the womb
29 Apr 2021, 3:11 p.m.
Scientists and doctors from GOSH and Toronto 'Sick Kids' have come together to take advantage of the regenerative properties of stem cells isolated from amniotic fluid.
International study finds gene therapy offers a potential cure to children born without an immune system
11 May 2021, 11:31 a.m.
An international team of researchers at GOSH and UCLA have developed a gene therapy that successfully treated 48 out of 50 children with a form of severe combined immunodeficiency
New insight into when CAR T is effective against childhood leukaemia
24 May 2021, 4 p.m.
Scientists studying the effectiveness of CAR T-cell therapies in children with leukaemia have discovered a small sub-set of T-cells that are likely to play a key role in whether the treatment is successful
Gene therapy offers hope to children with rare and fatal brain diseases
29 Jun 2021, 10 a.m.
Scientists and doctors at UCL GOS ICH and GOSH have given hope of a gene therapy cure to children with a rare degenerative brain disorder called Dopamine Transporter Deficiency Syndrome (DTDS)
Clinical trial improves outcomes for children on ventilators
24 Aug 2021, noon
Trial finds that a greater involvement of nurses, minimising sedation use and increasing daily testing to assess the child’s readiness to come off the ventilator significantly reduced the time on mechanical ventilation.
Great Ormond Street Hospital for Children (GOSH) and Sensyne have announced a new partnership to improve children’s lives using clinical artificial intelligence to analyse anonymised patient data.
UK’s first gene therapy baby celebrates 21st birthday
1 Oct 2021, 11 a.m.
The first child to be treated in the UK with gene therapy celebrates his 21st birthday this week, twenty years after having the pioneering treatment at Great Ormond Street Hospital for Children (GOSH).
NIHR “Your Path in Research” campaign highlights GOSH’s research staff
21 Oct 2021, 5 p.m.
Throughout the month we’ve been sharing some of the amazing research stories from right here at GOSH – highlighting just a handful of examples of the research projects that our staff are involved in across the hospital.
Building our understanding of how children with rheumatic disease react to coronavirus infection
27 Oct 2021, 4 p.m.
A new study has shown that, despite having immune dysfunction and often being on immunosuppressive treatments, children with autoimmune rheumatic diseases have a favourable immune response to common coronavirus infections.
Rare disease genome sequencing uncovers new diagnoses for patients
15 Nov 2021, 2:08 p.m.
A world-first scientific study with major involvement from GOSH, published in the New England Journal of Medicine, has shown that whole genome sequencing (WGS) can uncover new diagnoses for people across the broadest range of rare diseases.
Placenta protection from COVID-19 for unborn babies
23 Nov 2021, 4:20 p.m.
Unborn babies are mostly protected from COVID-19 by the placenta, but may become infected if their gut is exposed to the SARS-CoV-2 virus, reveals a new study from GOSH and UCL GOS ICH.
Lab-grown stomachs help to shed light on COVID-19 symptoms in children
3 Dec 2021, 12:40 p.m.
For the first time, an international team of scientists and doctors have used these advances to develop a lab-grown model of the human stomach. This can be used to study how infections in humans impact the gastrointestinal system.
Researchers and doctors at GOSH have long been at the forefront of developing new treatments for Spinal Muscular Atrophy (SMA) and new research this year is helping us understand how Zolgensma, a gene therapy, can help.
Researchers at GOSH and UCL are the first to identify 'pre-resistance' signs in bacteria, indicators that particular bacteria are likely to become resistant to antibiotics in the future. This will allow doctors in the future to select the best treatments
New funding enables vital research in childhood cancer treatment
5 Jan 2022, 3:53 p.m.
Special molecules called fluorophores could ‘light up’ living cancer cells in future treatment of neuroblastoma, with new research by our GOSH doctors underway.
Pre-screening for Spinal Muscular Atrophy could change lives
7 Jan 2022, 6 a.m.
A team from Great Ormond Street Hospital (GOSH) and the UCL GOS Institute of Child Health (ICH) have shown how ‘blood spot’ testing new-borns could identify children who will go on to develop Spinal Muscular Atrophy, (SMA).
Rapid immune response in children protects them from COVID-19
7 Jan 2022, 11 a.m.
Researchers at the NIHR Great Ormond Street Hospital (GOSH) BRC, UCL and the Wellcome Sanger Institute discover how differences in the immune response of adults and children can help to explain why children are less likely to fall seriously ill with COVID
