Trial suggests no adverse effects of vaginal progesterone prophylaxis for the prevention of preterm birth on child at age two
28 Jun 2016, 2:18 p.m.
Diagnostics and Imaging Theme Lead Professor Neil Sebire has teamed up with researchers from nine other establishments to carry out the largest randomised trial to investigate the long-term safety of vaginal progesterone prophylaxis for preterm births.
Using new wearable technology to monitor Niemann-Pick disease
22 Mar 2016, 4:15 p.m.
A smartphone app, combined with wearable technology, will allow doctors to remotely monitor patients with conditions that limit their ability to voluntarily move their muscles. The app, known as 'aparito', uses a motion-tracking writsband to record the mo
Wellcome Trust funding success for research into stem cells, gut disorders and the genetics of childhood conditions
23 Aug 2018, 5:01 p.m.
Prestigious Collaborative Award and Seed Award funding from the Wellcome Trust has been awarded to researchers at Great Ormond Street Hospital (GOSH) and the UCL Great Ormond Street Institute of Child Health (ICH). The awards will support pioneering labor
World first use of gene-edited immune cells to treat ‘incurable’ leukaemia
10 Nov 2015, 2:18 p.m.
A new treatment that uses ‘molecular scissors’ to edit genes and create designer immune cells programmed to hunt out and kill drug resistant leukaemia has been used at Great Ormond Street Hospital (GOSH).
Antibodies from the common cold could help protect against COVID-19
13 Nov 2020, 4:10 p.m.
Common cold antibodies, created by the immune system and found much more commonly in children aged between 6-16, could provide some protection against COVID-19.
GOSH researchers join experts in warning of the detrimental impact of a no deal Brexit on rare diseases
11 Dec 2020, 4:24 p.m.
Experts have warned that a ‘no deal’ Brexit will result in the exclusion of the UK from the 24 European Reference Networks (ERNs) that were established to improve the care of patients bearing the lifelong burden of a rare disease, which require highly spe
Leukaemia trial shows promise and complexity of genome-edited cell therapies
12 Dec 2020, 5:16 p.m.
A ‘one size fits all’ immune therapy developed at the UCL Great Ormond Street Institute of Child Health (ICH) could help to clear cancerous cells in children and adults who have exhausted all other treatment options for B-cell acute lymphoblastic leukaemi
New research finds that adult men are significantly more likely to need intensive care treatment for COVID-19
11 Dec 2020, 3:28 p.m.
Adult men have almost three times the odds of needing admission to intensive care and 40% higher odds of dying from COVID-19 than women, according to a new study led by researchers at UCL, Great Ormond Street Hospital and the University of Cape Town.
Scientists build whole functioning thymus from human cells
22 Dec 2020, 4:24 p.m.
Researchers from two leading national organisations have rebuilt a human thymus using human stem cells and a bioengineered scaffold thanks to support from the NIHR GOSH Biomedical Research Centre (BRC). Their work, which has been published in Nature Commu
The Research and Innovation Communications team at GOSH/the NIHR GOSH BRC invite you to enter our Research and Innovation Showcase: A Moment of Discovery.
3rd Annual NIHR GOSH BRC Image Competition - A Moment of Discovery
1 Nov 2023, noon
The Research and Innovation Communications team at GOSH and the NIHR GOSH Biomedical Research invite you to enter our Research and Innovation Showcase: A Moment of Discovery.
A guide for researchers by children and young people containing key principles which reflect children’s and young people’s views about when it is ok to link their data for research.
How linked health and education data is changing what we know about children with neurodisability
9 Feb 2026, 9:36 a.m.
Children with neurodisability often have complex health and educational needs, but population level data on long term outcomes remains limited. New research from GOS-ICH addresses this gap using one of the largest national birth cohorts to date.
48% increase in clinical research participants at GOSH
20 Jul 2018, 11:34 a.m.
The number of people taking part in research trials at Great Ormond Street Hospital (GOSH) has increased by 48 per cent, according to figures released this week by the National Institute for Health Research (NIHR).
Cannabidiol reduces seizures for children with complex epilepsies
14 Jun 2018, 8:49 p.m.
Cannabidiol, a drug derived from cannabis but with the psychoactive ingredients removed, has been shown to reduce seizures by around 40 % in children with a rare form of drug resistant epilepsy known as Lennox-Gastaut syndrome (LGS).
A UK-wide clinical trial looking at what is the best level of oxygen to aim for children who are on ventilation in intensive care is set to launch later this year.
Drug for rare form of rickets now available on the NHS
11 Jan 2019, 10:19 a.m.
A new, targeted treatment for the rare form of rickets called X-Linked Hypophosphataemia (XLH) is now available to NHS patients from 8 January 2019, following an international clinical trial.
European clinical trial for Kawasaki disease to be led by GOSH and ICH researchers
27 Jun 2019, 1:42 p.m.
Researchers at the UCL Great Ormond Street Institute of Child Health (ICH) and Great Ormond Street Hospital (GOSH) are to lead a new clinical trial for Kawasaki syndrome (KD-CAAP), a rare immune system condition that causes swelling of the blood vessels o
Genetic testing helps diagnose developmental disorders before birth
1 Feb 2019, 11:05 a.m.
Genetic sequencing improved the diagnosis of abnormalities detected in ultrasound scans of developing babies, in new research from Great Ormond Street Hospital (GOSH), the Wellcome Sanger Institute and Birmingham Women’s Hospital.
