Researchers have grown the world’s first oesophagus engineered from stem cells and successfully transplanted them into mice, in a pioneering new study led by Great Ormond Street Hospital (GOSH) and the UCL Great Ormond Street Institute of Child Health (ICH).
A novel cell death process known as necroptosis is responsible for the degeneration of muscle cells over time in Duchenne muscular dystrophy (DMD), according to new research from the National Institute for Health Research (NIHR) Great Ormond Street Hospital (GOSH) Biomedical Research Centre.
Prestigious Collaborative Award and Seed Award funding from the Wellcome Trust has been awarded to researchers at Great Ormond Street Hospital (GOSH) and the UCL Great Ormond Street Institute of Child Health (ICH). The awards will support pioneering laboratory-based research which will help shed light on the underlying genetic and molecular causes of rare childhood conditions.
A new film series, led by Great Ormond Street Hospital (GOSH), shines a spotlight on the bright future of children’s research, and highlights how pioneering clinical trials across the UK are helping develop new treatments for children with health conditions across the world.
Injections of the drug canakinumab significantly reduced the number of fever episodes in children with three different types of recurrent fever conditions, in an international trial led at GOSH by Professor Paul Brogan.
A new rapid sequencing technique has helped doctors at Great Ormond Street Hospital (GOSH) to quickly diagnose children in intensive care, enabling them to receive the best treatment and reducing the time they have to spend hospital.