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Scientists build whole functioning thymus from human cells

22 Dec 2020, 4:24 p.m.

Researchers from two leading national organisations have rebuilt a human thymus using human stem cells and a bioengineered scaffold thanks to support from the NIHR GOSH Biomedical Research Centre (BRC). Their work, which has been published in Nature Commu

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Role of important protein improves understanding of autoimmune diseases

22 Mar 2016, 4:59 p.m.

Researchers – led by Great Ormond Street BRC-supported Professor Tessa Crompton in collaboration with the Paediatric Department at Oxford University – have identified the role of a key protein in normal development of the thymus, an important organ of the

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Paula Thomas

Paula is an Eye Clinic Liaison Officer (ECLO) at Great Ormond Street Hospital. 

Paula provides any non-medical advice to parents, children and young adults around their visual impairment. 

Paula was once a patient at GOSH and reflects on how differe…

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50th patient treated with thymus transplant at GOSH

12 Apr 2021, 3:44 p.m.

The 50th patient was treated at Great Ormond Street Hospital for Children last month with a pioneering treatment to transplant otherwise-discarded thymus tissue into very young children who lack a working thymus.

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About the Thames Paediatric Anaesthetists Group (Thames PAG)

Welcome to the Thames Paediatric Anaesthetists Group (Thames PAG) website.

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Tissue engineering and regenerative medicine - our impact

Worldwide 7.9 million children a year are born with serious birth defects and many more develop progressive tissue damage in childhood that does not heal.

This theme builds on expertise in stem cell research and regenerative medicine.

Here you can rea…

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New funding to support pioneering thymus transplant research at GOSH

11 Jul 2018, 2:19 p.m.

Professors Graham Davies and Adrian Thrasher have been awarded funding from Great Ormond Street Hospital (GOSH) Charity to further develop a cutting-edge new treatment for children with the rare immunodeficiency condition complete DiGeorge syndrome (cDGS)

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BRC - Thomas Voit (Director)

Professor Thomas Voit is Director of the NIHR Great Ormond Street Hospital (GOSH) BRC, Professor and Honorary Consultant of Paediatrics at GOSH, and Vice-Dean for Enterprise at UCL’s Faculty of Population Health Sciences.

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North Thames Consortium (NTC)

The North Thames Consortium (NTC) is a collaboration between the NHS Trusts across North Central London, North West London and North East London in an attempt to build a diverse faculty and patient database and combine efforts in the provision of MRCPCH e

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North Thames Genomic Laboratory Hub

The NHS North Thames Genomic Laboratory Hub (NTGLH) is one of seven genomic laboratory hubs in England responsible for providing genomic and genetic testing, including the start of whole genome sequencing, as part of the Genomic Medicine Service in the NH

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Research and publications from the Anaesthesia department

The Anaesthesia Department is involved in a broad range of research. Current themes are listed below.

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Dr Emma Wakeling

Rare Disease Lead

Consultant in Clinical Genetics and Genomic Medicine

Dr Wakeling has been a consultant in clinical genetics at Great Ormond Street Hospital (GOSH) since 2019. Prior to this she was a consultant at North West Thames Regional Genetics …

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Meet the Thames Paediatric Anaesthetists Group

The Thames Paediatric Anaesthetists Group is co-ordinated by the following anaesthetists:

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Meet the Immunology team

The Immunology team at Great Ormond Street Hospital includes consultants, specialist nurses, junior doctors, psychologists, ward nurses and play specialists.

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Contact the North Thames Paediatric Epilepsy Network

Paediatrician – Chair: Dr Andrew Lloyd Evans (Northwick Park Hospital) Paediatrician – Deputy Chair: Dr Christina Petropolous (University College London Hospital)

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Combined immunodeficiency (CID) in children

This leaflet is designed to help answer the questions families may have about the immune condition called combined immunodeficiency (CID). It has been produced jointly by PID UK and the paediatric immunodeficiency centres at Great Ormond Street Hospital (

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