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Study reveals fresh insight on children's condition related to COVID-19

10 Jul 2020, 10 a.m.

A UK study into critically ill children admitted to paediatric intensive care units with symptoms of a rare, new inflammatory syndrome, has combined data from units across the country to offer the first nationwide insights into the true extent of the cond

Fresh perspectives from children and young people

29 Jul 2020, 4:35 p.m.

Talking to our young patients is so important. They tell us what works, what doesn’t, and how to improve what we do. Recently, we called on the expertise of our amazing patients to develop a series of videos about uveitis – a condition that causes inflamm

First targeted gene therapy for Wiskott-Aldrich Syndrome shows promise

12 Aug 2020, 10:02 a.m.

GOSH researchers have shown the power of gene editing technology CRISPR-Cas9 in correcting DNA ‘spelling mistakes’ that cause rare immune system conditions in children.

Patient Enzo

Lab-grown mini-organs could offer treatment hope for children with intestinal failure

7 Sep 2020, 4 p.m.

Pioneering scientists at Great Ormond Street Hospital (GOSH), the UCL Great Ormond Street Institute of Child Health (ICH) and the Francis Crick Institute have grown human intestinal grafts using stem cells from patient tissue that could one day lead to pe

Researchers grow functioning blood vessels from scratch

9 Sep 2020, 4 p.m.

Human cells ‘sent back in time’ to behave as they did in the womb can be used to grow networks of blood vessels in the laboratory, according to research by an international team including the UCL Great Ormond Street Institute of Child Health (ICH). The fi

Researcher with pipette

UCL GOS Institute for Child Health Gold Athena SWAN award

15 Oct 2020, 10:55 a.m.

Great Ormond Street Hospital’s academic partner, the UCL Great Ormond Street Institute for Child Health (GOS ICH), has been awarded GOLD status through Athena SWAN for its work to improve gender equality and diversity.

Great Ormond Street Hospital praised in mental health report

23 Oct 2020, 12:47 p.m.

Great Ormond Street Hospital’s (GOSH) mental health services team has been praised in a new report looking at inpatient mental health wards during the Covid-19 pandemic.

Researcher with pipette

Hope of better treatments for rare childhood cancer as disease origin is uncovered

5 Nov 2020, 9:16 a.m.

GOSH researchers are part of a team of scientists who have identified how a rare form of childhood cancer may originate, according to a new study published today in the New England Journal of Medicine.

GOSH celebrates one year anniversary of the opening of the Zayed Centre for Research into Rare Diseases in Children

16 Nov 2020, 10:35 a.m.

It’s been a year since the Zayed Centre for Research opened its doors to patients, clinicians and researchers from across Great Ormond Street Hospital (GOSH) and UCL, and to celebrate we’re taking a look back at its work and achievements.

Inflammatory syndrome in children is not caused by a special strain of coronavirus

16 Nov 2020, 1:38 p.m.

The world’s first genetic study of coronavirus from children with inflammatory syndrome PIMS-TS, led by researchers at the UCL Great Ormond Street Institute of Child Health (ICH), suggests characteristics of the human host, rather than of the virus itself

Inflammatory syndrome in children is not caused by a special strain of coronavirus

16 Nov 2020, 1:38 p.m.

The world’s first genetic study of coronavirus from children with inflammatory syndrome PIMS-TS, led by researchers at the UCL Great Ormond Street Institute of Child Health (ICH), suggests characteristics of the human host, rather than of the virus itself

Image pre-COVID-19

GOSH surgeons perform revolutionary eye gene therapy

17 Nov 2020, 4:03 p.m.

(Image above taken pre-COVID-19) Surgeons at Great Ormond Street Hospital (GOSH) have carried out pioneering eye gene therapy treatment for rare form of genetic blindness following 10 years of research.

Promising early results in CAR T-cell trial for common childhood cancer

30 Nov 2020, 6 p.m.

Results from a phase I clinical trial Involving the UCL Great Ormond Street Institute of Child Health (ICH) show that CAR T-cell therapy could achieve activity against neuroblastoma tumours, opening the door to progress this approach towards further clini

Ancient gene mutation found as the cause of rare hereditary condition for GOSH patient

18 Jan 2021, 5:11 p.m.

UK scientists have found that a 7,000-year-old genetic mutation is responsible for a rare form of hereditary motor neuropathy (HMN).

Zoe Bull

GOSH-led metformin trial dramatically reduces seizures for people with Tuberous Sclerosis

2 Feb 2021, 4:28 p.m.

A team of researchers led by UCL Great Ormond Street Institute of Child Health (ICH) and Great Ormond Street Hospital (GOSH) has found that metformin – a drug commonly used to treat Type 2 diabetes – can successfully reduce symptoms associated with …

International Day of Women and Girls In Science | YPAG

International Day of Women and Girls in Science 2021

11 Feb 2021, 10:39 a.m.

Carrying out research into the best way to fight children’s illnesses has been one of our main ambitions ever since GOSH opened in 1852. We wanted to take this opportunity of International Day of Women and Girls in Science 2021 to highlight just som…

RDD 2021 banner

Rare Disease-Day 2021

28 Feb 2021, 7 a.m.

Rare Disease Day is an international day celebrated in over 100 countries to raise awareness amongst the general public, the clinical community, and decision-makers about rare diseases and their impact on people affected and their families.

300 million people globally will suffer from a rare disease at some point in their lives

Global collaborative announced to develop new treatments for paediatric diseases

25 Feb 2021, 7 a.m.

Ahead of Rare Disease Day 2021, GOSH will join forces with three other leading children’s research institutions on three continents to decipher paediatric illnesses, including rare diseases, and find better treatments.

developing mouse spinal cord

Uninherited mutations cause spina bifida

19 Feb 2021, 4:53 p.m.

Scientists at the UCL GOS Institute of Child Health reveal that new genetic mutations which occur during embryonic development can cause the severe birth defect spina bifida. Many genes have been implicated in spina bifida, and mutations which are n…

MRI scan of fetus

MRI scans more precisely define and detect some abnormalities in unborn babies

17 Mar 2021, 10:57 a.m.

MRI scanning can more precisely define and detect head, neck, thoracic, abdominal and spinal malformations in unborn babies, finds a large multidisciplinary study led by Evelina London Children’s Hospital, Great Ormond Street Hospital and UCL.

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