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This displays the latest news items related to the Biomedical Research Centre.

Research suggests need for long-term follow-up for patients with Kawasaki Disease

Kawasaki disease is a rare condition that causes blood vessels to become inflamed and swollen. It predominantly occurs in children under the age of five. If left untreated, it results in balloon-like swellings (aneurysms) in the coronary vessels of approximately 25% of cases. To date, the cause of this disease remains unknown.

How to purify photoreceptors from retina grown in a dish

Work recently published in Stem Cells has shown that photoreceptor cells can be grown and purified in the lab before being transplanted into a mature host retina. This research, led by BRC-supported Professor Jane Sowden, suggests that cell replacement therapy involving the transplantation of new photoreceptor cells, isolated from retina grown in a dish, may be a possible treatment for blindness.

Clinical trial for a new stem-cell based therapy for a rare skin condition proves promising

Promising findings from a trial for a new stem-cell based therapy for a rare skin condition have been published in the Journal of Investigative Dermatology. The study, which involved intravenous injections of stem-cells, has led to an improvement in the quality of life for the subjects and their carers.

Funding provided to develop new therapy for acute liver failure

BRC-supported researcher Dr Kevin Mills has been awarded funding from the NIHR to investigate the regenerative ability of the liver following acute liver failure (ALF). If successful, the team hope that their research will lead to a novel therapy that could buy patients enough time to allow their livers to regenerate naturally, avoiding the need for liver transplants

Accelerated approval request for a new drug for a rare childhood muscle disorder

A drug for Duchenne Muscular Dystrophy (DMD), originally developed by BRC Theme Lead Professor Francesco Muntoni’s Consortium in the UK, has been filed by Sarepta Therapeutics for accelerated approval by the United States Food and Drug Adminstration (FDA).

Protein responsible for rare childhood disorder gives clues to common neurodegenerative conditions

A new mutation in the protein STAT2 has been identified in patients with mitochondrial disease. These findings could also be beneficial for more common neurodegenerative diseases, including Alzheimer’s, Huntington’s and Parkinson’s diseases.