BRC news

BRC latest news

This displays the latest news items related to the Biomedical Research Centre.

GOSH awarded £37 million funding to carry out pioneering paediatric research

The NIHR Great Ormond Street Biomedical Research Centre (BRC) has been awarded £37 million in funding to drive forward translational research into rare diseases in children. The Centre is the only one of its kind in the UK dedicated to paediatric research.

New technique to aid diagnosis of glycosylation disorders present at birth

A study, supported by the NIHR Great Ormond Street BRC, investigated the use of a 2D-differential gel electrophoresis (DIGE) method that provides a global analysis of the serum glycoproteome (glycomic profiling). 2D-DIGE allows multiple samples to be run simultaneously, eliminating gel-to-gel variations, and allowing direct overlay comparisons.

Trial suggests no adverse effects of vaginal progesterone prophylaxis for the prevention of preterm birth on child at age two

Diagnostics and Imaging Theme Lead Professor Neil Sebire has teamed up with researchers from nine other establishments to carry out the largest randomised trial to investigate the long-term safety of vaginal progesterone prophylaxis for preterm births.

Clinical trial to investigate treatment of acute lymphoblastic leukaemia to open at GOSH

A Phase I clinical trial (CARPALL) has opened at Great Ormond Street Hospital (GOSH) to investigate the use of immunotherapy with genetically modified T cells for acute lymphoblastic leukemia (ALL). The trial is led by Professor Persis Amrolia, who is supported by the NIHR Great Ormond Street BRC.

Reduced risk of pulmonary embolism in children treated with long term parenteral nutrition

Researchers at Great Ormond Street Hospital (GOSH) have shown a reduction in the incidence of pulmonary embolism in patients receiving parenteral nutrition after the introduction of a new mixed intravenous lipid emulsion.

Dr Wendy Heywood awarded investigator initiated research proposal from Shire Pharmaceuticals

Following NIHR Great Ormond Street BRC support, which led to the creation of a high-throughput targeted proteomic urine test, Dr Wendy Heywood has been awarded an industry investigator initiated award from Shire Pharmaceuticals.