https://www.gosh.nhs.uk/wards-and-departments/departments/clinical-specialties/immunology-information-parents-and-visitors/refer-patient-immunology-department/

Refer a patient to the Immunology department

The Immunology department at Great Ormond Street Hospital (GOSH) is part of the University College London (UCL) Centre for Immunodeficiency. This comprises adult and paediatric clinical services, diagnostic laboratories and research.Please see our admission criteria for information about the diagnoses treated by the Immunology department at GOSH.

How to refer a patient

For an outpatient appointment

As a tertiary care hospital, all children who attend GOSH must be referred via local hospital consultants, community paediatricians or in certain circumstances via a GP.

To make a referral please email gos-tr.referrals@nhs.net or fax 020 7813 8310.

International referrals are also received from a variety of countries.

For urgent out-of-hours admissions please contact the GOSH switchboard on 020 7405 9200 and ask for the on-call immunology consultant.

How to get advice

For patients known to GOSH

During office hours please contact the immunology secretary on 020 7829 8834. Alternatively, contact the GOSH switchboard on 020 7405 9200 and ask for the Immunology department.

Out of hours, please contact the GOSH switchboard on 020 7405 9200 and ask for the immunology registrar.

For patients not known to GOSH

During office hours please contact the immunology secretary on 020 7829 8834. Alternatively, contact the GOSH switchboard on 020 7405 9200 and ask for the Immunology department.

Out of hours, please contact the GOSH switchboard on 020 7405 9200 and ask for the immunology registrar.

Key staff members

Consultants

Professor Bobby Gaspar, GOSHCC Professor of Paediatrics and Immunology and Honorary Consultant in Paediatric Immunology
Special interest(s): X-linked lymphoproliferative syndrome and other EBV-related PIDs; Bone marrow transplantation and gene therapy for PID
Bobby.Gaspar@gosh.nhs.uk

Professor David Goldblatt, Professor of Vaccinology and Immunology and Honorary Consultant in Paediatric Immunology
Special interest(s): Chronic Granulomatous Disease
David.Goldblatt@gosh.nhs.uk

Professor Adrian Thrasher, Professor in Paediatric Immunology and Honorary Consultant Immunologist
Special interest(s): Wiskott Aldrich syndrome; Gene therapy for PID 
Adrian.Thrasher@gosh.nhs.uk 

Dr Siobhan Burns, Senior Clinical Lecturer and Honorary Consultant in Paediatric Immunology
Siobhan.Burns@gosh.nhs.uk 

Dr Amel Hassan, Associate Specialist Paediatric Immunologist
Amel.Hassan@gosh.nhs.uk

Nursing staff

Services and facilities available

The Immunology department offers diagnosis and management of all degrees of severity of primary immunodeficiency.

The team offers inpatient, outpatient and day case services.

Services are also provided for children with a variety of other immunological disorders (excluding allergy).

Children with immunodeficiency are managed by the medical/specialist nursing team, on a shared care basis with local paediatricians, community nurses, and in some cases GPs.

The Immunology department at GOSH offers a comprehensive diagnostic and treatment service for children from birth to 16 years with suspected or confirmed primary immunodeficiency.

Severe immunodeficiencies

Severe immunodeficiencies for which stem cell transplantation or gene therapy may be appropriate:

all forms of severe combined immunodeficiency (SCID)*

other (as yet molecularly undefined) combined immunodeficiencies

X-linked Hyper-IgM syndrome (CD40 ligand deficiency)

Wiskott-Aldrich syndrome

X-linked lymphoproliferative syndrome

haemophagocytic lymphohistiocytosis

chronic granulomatous disease

Chediak-Higashi syndrome

leucocyte adhesion deficiencies

some forms of Hyper IgE

*All infants affected by SCID require corrective therapy. For all other disorders each child is individually assessed regarding the need for transplantation/gene therapy.

Primary immunodeficiencies

Primary immunodeficiencies not usually requiring transplantation:

common variable immunodeficiency (CVID)

X-linked agammaglobulinemia (XLA)

transient hypogammaglobulinemia of infancy

selective IgA deficiency

IgG subclass deficiency (usually associated with IgA deficiency)

C1 esterase inhibitor deficiency (hereditary angioedema)

hyper-IgE syndrome (Job’s syndrome)

other neutrophil disorders

ataxia telangiectasia

Other immunological disorders

periodic fever syndromes

vasculitis

autoimmune lymphoproliferative syndrome

Bone marrow transplant (BMT)

The Immunology department works in close collaboration with the BMT unit, providing one of the two supra-regionally funded UK services for BMT for severe immunodeficiency.

This is one of the largest centres for BMT for primary immunodeficiency worldwide.

Other clinics and services

There are specialist clinics for certain disorders and dedicated BMT follow-up clinics.

Joint clinics are held with several related sub specialties and outreach clinics are held in a number of other centres.

For children requiring replacement immunoglobulin we work closely with local teams to either train parents to administer treatment at home, or for it to be provided close to home in local hospitals.

There is a dedicated nurse for this service.

Feedback and suggestions

All general feedback and suggestions can be directed to:

Immunology Secretary
Level 3

Zayed Centre For Research
Great Ormond Street Hospital
Great Ormond Street
London
WC1N 3JH

Telephone number: 020 7829 8834/7813/8121

Management contacts

Professor Bobby Gaspar
Specialty Lead for Immunology
Bobby.Gaspar@gosh.nhs.uk

Charlotte Stevens
Service Manager
020 7405 9200 Ext 4342
charlotte.stevens@gosh.nhs.uk

Esther Dontoh
General Manager
020 7405 9200 Ext 5096
esther.dontoh@gosh.nhs.uk

Special interest(s): BMT; Cellular therapies

Useful links