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Monobloc advancement with or without using a rigid external distraction (RED) frame

Monobloc advancement is an operation to reshape the front portion of the skull and face including the upper jaw to correct an abnormal head shape. This page from Great Ormond Street Hospital (GOSH) explains about the operation called monobloc advancement

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Neuropathic pain medicines

This page from Great Ormond Street Hospital (GOSH) explains about medicines used to treat neuropathic pain – pain caused by the nerves sending wrong signals to and from the brain. At GOSH, we mainly use amitriptyline, gabapentin and pregabalin, although o

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Neuropathic pain medicines

This information from Great Ormond Street Hospital (GOSH) explains about medicines used to treat children and young people with neuropathic pain  – pain caused by the nerves sending wrong signals to and from the brain. At GOSH, we mainly use amitriptyline

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ANT test update

Accelerating novel therapies - our impact

In this theme we will build our capacity to offer clinical trial options to children affected by rare and complex conditions who have limited treatment options. To do this we will invest in more staff who are trained to deliver specialist treatments…

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Intramedullary rodding surgery for children with Osteogenesis Imperfecta (OI)

Children and young people with Osteogenesis Imperfecta (OI) are more likely to develop fractures and bony changes such as bowing (bending) and shortening. Rodding surgery may be suggested or recommended by your child’s medical team. This page from Great O

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Our impact

Our BRC research programmes are already demonstrating clinical impact and benefit to patients treated at GOSH.

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Common difficulties seen in children with Sturge Weber Syndrome

Children with Sturge Weber Syndrome (SWS) have a range of disabilities and associated problems which can vary in severity. Some children have development within the average range. The outlook varies greatly from child to child, depending on the seve…

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Understanding how we test samples for infection in our laboratories

When someone has an infection, germs including bacteria, viruses or fungi invade the body, causing signs like fever and chills, aches and pains, and feeling generally unwell. Bacteria, viruses and fungi can show up in body fluids, such as blood, urine (we

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Generalised lymphatic anomaly (GLA)

Generalised lymphatic anomaly (GLA) – previously known as lymphangiomatosis – is the name given to a rare, congenital (present at birth), and progressive disorder of lymphatic channels which can affect different organs including the bones and the intestin

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X-linked lymphoproliferative disorder (XLP1)

X-linked lymphoproliferative type 1 (XLP1) disorder is a rare immune condition that affects around 1 in every 1 million males.This page has been produced jointly between PID UK, Great Ormond Street Hospital (GOSH) and the Great North Children’s Hospital.

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Senior research associate Giovanni Giuseppe Giobbe, Marta Gazzaneo, Lucy Holland and Giada Benedetti standing together in the ZCR

A moment of discovery: extraordinary images showcase research at GOSH

29 Feb 2024, 9 a.m.

A vibrant image helping researchers' study gastrointestinal diseases and their potential treatments has been crowned the winner of the 3rd annual National Institute for Health and Care Research Great Ormond Street Hospital Biomedical Research Centre (NIHR

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Orbital box osteotomy

Orbital box osteotomy is an operation used to correct abnormal eye socket shape or placement. This page from Great Ormond Street Hospital (GOSH) explains about the operation called orbital box osteotomy, which is used to treat craniofacial disorders. It e

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Research and publications from the Wolfson Neurodisability Service

The Wolfson Neurodisability Service is involved in a broad range of research across all clinics.

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Selective Dorsal Rhizotomy clinical outcomes

Clinical outcomes are measurable changes in health, function or quality of life that result from our care. Constant review of our clinical outcomes establishes standards against which to continuously improve all aspects of our practice.

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Fronto-orbital remodelling

Fronto-orbital remodelling is an operation to reshape the bones at the front of the skull and above the eye sockets to correct an abnormal head shape. It also enlarges the space within the skull to allow the brain to grow and develop and is used to treat

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Gene, stem and cellular therapies awards

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Posterior vault expansion

A posterior vault expansion operation is a type of operation used to enlarge the space within the skull to allow the brain to grow and develop. This page from Great Ormond Street Hospital (GOSH) explains about the posterior vault expansion operation, whic

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Trust Board

Find out more about Great Ormond Street Hospital's Trust Board.

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FOI disclosure log 2020

Here you can read our responses to the Freedom of Information Requests we have received. This content is updated monthly. Select the rows below to view the requests for each month.

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Resuscitation: basic life support of babies and children with a tracheostomy

Each year, a number of babies and children will suffer an accident or illness severe enough to stop them breathing (respiratory arrest). In a small number of these cases, it will even stop their heart beating (cardiac arrest).

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