Corticosteroids for children with neuromuscular disorders
This information has been provided to help answer some of the questions you may have about steroid medication for children with neuromuscular disorders.
Toddler doing well after receiving newest gene therapy available on NHS
25 Jun 2025, 9:23 a.m.
A toddler with a life-limiting and life-threatening rare disease is the youngest to be treated with the newest gene therapy available on the NHS at GOSH.
Multiple sclerosis (MS) is a common neurological condition affecting around 100,000 adults in the UK, but it is rare in childhood – and particularly rare in children under 12. Specialist care for these children and young people is therefore crucial and Gr
Back for 2026: NIHR GOSH BRC Research Communications Internship
OPEN: Our NIHR Great Ormond Street Biomedical Research Centre is delighted to open the 2026 call for applications for a Research Communications Internship for existing staff of UCL GOS ICH
NIHR GOSH BRC Research Communications Internship 2023
CLOSED: Our NIHR Great Ormond Street Biomedical Research Centre is delighted to open the first call for applications for a Research Communications Internship for existing staff of GOSH or UCL GOS ICH, specialising in social media.
Children are incredibly active and they have little sense of danger so it is not surprising that they are prone to head injuries. In addition, their heads are large in proportion to their bodies and therefore more vulnerable to damage than adult heads. Th
Monobloc advancement with or without using a rigid external distraction (RED) frame
Monobloc advancement is an operation to reshape the front portion of the skull and face including the upper jaw to correct an abnormal head shape. This page from Great Ormond Street Hospital (GOSH) explains about the operation called monobloc advancement
This page from Great Ormond Street Hospital (GOSH) explains about medicines used to treat neuropathic pain – pain caused by the nerves sending wrong signals to and from the brain. At GOSH, we mainly use amitriptyline, gabapentin and pregabalin, although o
This information from Great Ormond Street Hospital (GOSH) explains about medicines used to treat children and young people with neuropathic pain – pain caused by the nerves sending wrong signals to and from the brain. At GOSH, we mainly use amitriptyline
In this theme we will build our capacity to offer clinical trial options to children affected by rare and complex conditions who have limited treatment options. To do this we will invest in more staff who are trained to deliver specialist treatments…
Intramedullary rodding surgery for children with Osteogenesis Imperfecta (OI)
Children and young people with Osteogenesis Imperfecta (OI) are more likely to develop fractures and bony changes such as bowing (bending) and shortening. Rodding surgery may be suggested or recommended by your child’s medical team. This page from Great O
Common difficulties seen in children with Sturge Weber Syndrome
Children with Sturge Weber Syndrome (SWS) have a range of disabilities and associated problems which can vary in severity. Some children have development within the average range. The outlook varies greatly from child to child, depending on the seve…
Understanding how we test samples for infection in our laboratories
When someone has an infection, germs including bacteria, viruses or fungi invade the body, causing signs like fever and chills, aches and pains, and feeling generally unwell. Bacteria, viruses and fungi can show up in body fluids, such as blood, urine (we
Generalised lymphatic anomaly (GLA) – previously known as lymphangiomatosis – is the name given to a rare, congenital (present at birth), and progressive disorder of lymphatic channels which can affect different organs including the bones and the intestin
X-linked lymphoproliferative type 1 (XLP1) disorder is a rare immune condition that affects around 1 in every 1 million males.This page has been produced jointly between PID UK, Great Ormond Street Hospital (GOSH) and the Great North Children’s Hospital.
A moment of discovery: extraordinary images showcase research at GOSH
29 Feb 2024, 9 a.m.
A vibrant image helping researchers' study gastrointestinal diseases and their potential treatments has been crowned the winner of the 3rd annual National Institute for Health and Care Research Great Ormond Street Hospital Biomedical Research Centre (NIHR
Orbital box osteotomy is an operation used to correct abnormal eye socket shape or placement. This page from Great Ormond Street Hospital (GOSH) explains about the operation called orbital box osteotomy, which is used to treat craniofacial disorders. It e
Clinical outcomes are measurable changes in health, function or quality of life that result from our care. Constant review of our clinical outcomes establishes standards against which to continuously improve all aspects of our practice.
