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Ground-breaking study that utilises mRNA technology shows hope for rare disease treatment

18 Jan 2024, 11 a.m.

Explore ground-breaking research at the intersection of Covid-19 vaccine technology and rare disease therapy.

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GOSH collaborating in pioneering PHEMS project to revolutionise use of health data across Europe

18 Jan 2024, 10:42 a.m.

GOSH is one of six leading European children’s hospitals that make up the PHEMS project, which will revolutionise how children’s health data is managed and used across Europe and advance research and innovation in healthcare for children.

Staff working at cell and Gene therapy clean room at the ZCR

172 years of leaps in medical science at GOSH

14 Feb 2024, 6 a.m.

Today on Wednesday 14 February, GOSH is celebrating its 172nd birthday. With 2024 being a leap year, we wanted to look back at some of the leaps that we have made in medical science over the past 172 years

Senior research associate Giovanni Giuseppe Giobbe, Marta Gazzaneo, Lucy Holland and Giada Benedetti standing together in the ZCR

A moment of discovery: extraordinary images showcase research at GOSH

29 Feb 2024, 9 a.m.

A vibrant image helping researchers' study gastrointestinal diseases and their potential treatments has been crowned the winner of the 3rd annual National Institute for Health and Care Research Great Ormond Street Hospital Biomedical Research Centre (NIHR

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Stem cells collected in late pregnancy herald advances in prenatal medicine

4 Mar 2024, 4 p.m.

A new pioneering approach, developed by researchers at UCL and Great Ormond Street Hospital means human development can be observed in late pregnancy for the first time

Adult helping a child in goggles with a pipette

Raising awareness on Rare Disease Day

8 Mar 2024, 12:04 p.m.

To celebrate Rare Disease Day we invited patients and their families to try out 13 different hands-on and interactive fun and educational science and research activities for children and adults.

First-of-its-kind study into the Ketogenic diet

2 Apr 2024, 10 a.m.

A ketogenic diet, which is low in carbohydrates and high in fat, shows promise as an alternative treatment option for infants with drug-resistant epilepsy.

New plan announced to get more children access to gene therapy treatments

9 Apr 2024, 9 a.m.

Great Ormond Street Hospital (GOSH) has announced plans to revolutionise how children living with a rare disease can gain access to life-changing treatments.

Human nasal cells cultured in a petri dish

New study finds that nasal cells protect against Covid-19 in children

18 Apr 2024, 9:20 a.m.

New research shows that children are less likely than adults to develop severe COVID because cells in their nose are better at fighting off the virus.

New cheek swab test helping to monitor children with rare heart condition

22 Apr 2024, 9:49 a.m.

A cheap and simple test, being developed with funding from the British Heart Foundation (BHF), will allow quick and safe monitoring in children with arrhythmogenic cardiomyopathies (ACM).

Help pioneer new treatments for millions of people this DNA Day

23 Apr 2024, 9:41 a.m.

DNA Day is coming up this Thursday (25 April) and the team behind the DNA, Children + Young People’s Health Resource (D-CYPHR) are encouraging children and young people to contribute to important health research.

animation of a computer screen with patient health data

Two years of advancing personalised healthcare for children in collaboration with Roche

29 Apr 2024, noon

As we mark the milestone of our second year working together with Roche, we took some time to reflect on the incredible progress we have made in our journey towards advancing personalised healthcare for children.

Aaliyah out for the day with her family.

New treatment for brain tumour approved after over 20 years of research

24 Apr 2024, 8 a.m.

The first-ever targeted treatment for brain tumours in children has been approved for NHS patients, following decades of research by a Great Ormond Street consultant.

A man is sat in a laboratory at a table with a microscope in front of him while clad in a white laboratory coat.

GOSH Surgeon Paolo De Coppi makes first TIME100 Health List

2 May 2024, 2 p.m.

Professor Paolo De Coppi has been added to TIME's inaugural TIME100 Health List of the 100 most influential people in global health this year

A boy walks along the beach with the sunset and sea behind him. The sky is a rainbow of colours

New blood test could prevent sudden deaths for children living with hereditary heart condition

10 Jun 2024, 9 a.m.

A new blood test that could identify children with a potentially fatal heart condition has been developed by researchers at UCL (University College London) and Great Ormond Street Hospital (GOSH)

child on a slide that looks like a rainbow and says 'Clean Air Day'

Studying the impact of environments on child health by linking big data

20 Jun 2024, 8 a.m.

At GOSH we know that we're not caring for children if we're not caring for the environment. We spoke to Professor Pia Hardelid, who told us about a project which is helping us to understand the impacts of local environments on children’s health.

The image shows a montage of three children. The first is sat on a merrygo round, the next is saving a goal and the third is laughing at something off camera.

Researchers have designed a new genetic therapy that could be used to reverse large and painful giant moles after further studies.

17 Jun 2024, 2 p.m.

Researchers have designed a new genetic therapy that could be used to reverse large and painful giant moles after further studies.

Important step forward in stem cell therapy for rare bowel disease

27 Jun 2024, 11:15 a.m.

A new study led by researchers at UCL Great Ormond Street Institute of Child Health (UCL GOS ICH) and the Centre for Stem Cell Biology, University of Sheffield, has demonstrated the potential of stem cell therapy to treat those with Hirschsprung disease.

A droplet of colourless liquid hangs of the end of a conical tip above a plastic tube. The plastic tip is held in a blue rack that is beginning to go out of focus

Blood test and AI could predict Parkinson’s seven years before symptoms

18 Jun 2024, 4 p.m.

International researchers have developed a simple blood test that uses artificial intelligence to predict Parkinson’s up to seven years before the onset of symptoms, part-supported by the NIHR GOSH BRC

A teenage boy in a green jacket with orange trim sit astride a muddy bike. He is smiling broadly at the camera, even though he is mud spattered and he is wearing a helmet which is also mud-splattered. He's on a track that looks like a country path.

First UK trial of Deep Brain Stimulation for children with epilepsy begins at GOSH

24 Jun 2024, 9 a.m.

Discover how Oran became the first UK patient in a clinical trial using deep brain stimulation (DBS) for epilepsy. Learn about his 80% reduction in daytime seizures thanks to this innovative DBS treatment.