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PAS (periodic acid–Schiff) stained glomeruli showing reduced scarring (deep pink) following ultrasound guided renal artery injection of Angpt1 nanocomplexes.

New study brings hope for children with rare life-threatening kidney disease

27 Aug 2026, 9:19 a.m.

New research funded by Great Ormond Street Hospital Charity (GOSH Charity), LifeArc and Kidney Research UK has taken an important step towards developing a new treatment for serious genetic kidney diseases affecting children.

A group of researchers are working in the lab

Four research projects receive funding to improve understanding and treatment of childhood cancer

4 Sep 2026, 11:40 a.m.

Researchers at Great Ormond Street Hospital (GOSH) and UCL Great Ormond Street Institute of Child Health (UCL GOS ICH) have received funding from The Little Princess Trust for four childhood cancer research projects.

2 photos side by side of bronze sink pipes with horizontal bends. The left one is slightly largers

From staff idea to global innovation: Taking the next step towards improving patient safety

7 Sep 2026, 2:59 p.m.

A simple idea developed by a GOSH clinician has secured a commercial partner.

Five GOSH clinicians recognised with professorial appointments at UCL

17 Sep 2026, 4:13 p.m.

Five clinician researchers from GOSH have been promoted to professor by University College London (UCL), recognising their outstanding contributions to research, innovation and child health.

A clinician is checking a child's eyes using a imaging device

Innovative imaging project aims to save children’s sight

21 Sep 2026, 11:32 a.m.

Researchers from GOSH and UCL are leading a project that could transform how children at risk of sight loss are monitored, by adapting advanced eye imaging technology for use closer to home

Four people wearing lab coats holding pipettes

Researchers funded to cure inflammatory disease

23 Sep 2026, 10:01 a.m.

Researchers from University College London (UCL) and Great Ormond Street Hospital (GOSH) will join researchers across the UK and international partners in a bid to transform how chronic inflammatory disease is treated.

Photo of a man with a beard, wearing a pink shirt, blue tie and white lab coat. He is standing in front of a microscope

GOSH surgeon receives prestigious international award

28 Sep 2026, 10:01 a.m.

Professor Paolo De Coppi, Consultant Paediatric Surgeon at Great Ormond Street Hospital (GOSH), has been recognised as an Honorary Fellow of the American College of Surgeons (ACS), one of the most prestigious honours in global surgery.

A baby cuddles up with his parents and everyone is smiling

Thousands join world-first trial to save lives of critically ill children

12 Oct 2026, 10:11 a.m.

Some of the sickest children in the UK have started to join an innovative clinical trial designed to improve the survival and recovery of children requiring intensive care treatment, led by GOSH.

A group of adults are gathered around a table of papers, laughing and interacting

GOSH families at the heart of major £6m project to improve support for children with complex needs

15 Oct 2026, 11:35 a.m.

Children, young people and families from GOSH will help shape a major new research programme

Unidentified person cutting out letters for an arts project, May 2017

Good Hope Works at GOSH

17 May 2017, 12:53 p.m.

Good Hope Works is an exciting creative research project facilitated by GOSH Arts and undertaken by artist Joanna Brinton. The project has engaged staff from across Great Ormond Street Hospital (GOSH) and will culminate in the installation of a permanent

£1 million award to push forward regenerative medicine research

13 Dec 2018, 10:19 a.m.

Researchers at Great Ormond Street Hospital (GOSH) and the UCL Great Ormond Street Institute of Child Health (ICH) are to lead a new collaboration exploring how stem cells can be engineered to evade immune responses.

AI bodysuit trial launched to help treat Duchenne muscular dystrophy

1 Feb 2018, 11:57 a.m.

A new artificially intelligent bodysuit to help understand how mobility is affected in boys with Duchenne will be trialled in a collaboration between researchers at Great Ormond Street Hospital (GOSH) and Imperial College London.

A liquid handling robot appears placing ampules into laboratory trays.

BRC researchers part of collaboration to improve efficiency of gene therapy products

26 Jul 2018, 3:56 p.m.

A new collaboration aiming to develop advanced technologies for manufacturing ex vivo gene therapy products has been established between researchers at UCL Great Ormond Street Institute of Child Health (ICH) and Plasticell, a developer of stem cell techno

Meredyth Wilkinson, one of the study's first authors

Cutting edge new method reveals novel cause of Juvenile dermatomyositis

25 Jun 2018, 10:18 a.m.

A new in-depth method has helped shed light on the key role of B cells, a type of immune cell, in the rare childhood condition Juvenile dermatomyositis (JDM).

Driving forward medical device development

2 Oct 2019, 4:57 p.m.

The NIHR GOSH BRC last month hosted an inaugural medical devices workshop, in partnership with the UCL Institute of Healthcare Engineering.

Drug for Duchenne Muscular Dystrophy shows promise in clinical trial

21 Aug 2017, 12:02 p.m.

An international clinical trial has found that the drug ataluren can improve mobility for children with a severe form of Duchenne muscular dystrophy (DMD).

Film celebrates success of Biomedical Research Centres set up by outgoing UK Chief Medical Officer

14 Oct 2019, 11:37 a.m.

NHS patients who have taken part in clinical trials have expressed their gratitude to researchers in a film celebrating the work of the National Institute for Health Research (NIHR) Biomedical Research Centres (BRCs), including GOSH BRC, to mark the retir

First children have gene therapy treatment for blindness at GOSH

18 Feb 2020, 5:33 p.m.

The first paediatric patients have received a pioneering new gene therapy that can restore eyesight at Great Ormond Street Hospital.

Phoebe and Fenella took part in a clinical trial at GOSH

First drug to reduce fever flares in children with recurrent fever conditions

17 Aug 2018, 12:02 p.m.

Injections of the drug canakinumab significantly reduced the number of fever episodes in children with three different types of recurrent fever conditions, in an international trial led at GOSH by Professor Paul Brogan.

Test tubes on a revolving plate in a lab

Funding boost to develop novel therapy for rare metabolic condition

1 Apr 2019, 10:19 a.m.

GOSH and UCL Great Ormond Street Institute of Child Health (ICH) researchers Professor Paul Gissen and Dr Julien Baruteau will be part of a new collaboration with Evox Therapeutics that aims to develop a new therapy for the life threatening metabolic cond