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Stem cells collected in late pregnancy herald advances in prenatal medicine

4 Mar 2024, 4 p.m.

A new pioneering approach, developed by researchers at UCL and Great Ormond Street Hospital means human development can be observed in late pregnancy for the first time

Senior research associate Giovanni Giuseppe Giobbe, Marta Gazzaneo, Lucy Holland and Giada Benedetti standing together in the ZCR

A moment of discovery: extraordinary images showcase research at GOSH

29 Feb 2024, 9 a.m.

A vibrant image helping researchers' study gastrointestinal diseases and their potential treatments has been crowned the winner of the 3rd annual National Institute for Health and Care Research Great Ormond Street Hospital Biomedical Research Centre (NIHR

Staff working at cell and Gene therapy clean room at the ZCR

172 years of leaps in medical science at GOSH

14 Feb 2024, 6 a.m.

Today on Wednesday 14 February, GOSH is celebrating its 172nd birthday. With 2024 being a leap year, we wanted to look back at some of the leaps that we have made in medical science over the past 172 years

Child with Norrie Disease playing in a parachute with two adults

Patients, families, clinicians and researchers learn together on rare blinding condition

18 Jan 2024, 1:52 p.m.

Last December, the Norrie Disease conference took place at University College London, Great Ormond Street Institute of Child Health, organised by the Norrie Disease Foundation and Professor Jane Sowden’s research group.

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GOSH collaborating in pioneering PHEMS project to revolutionise use of health data across Europe

18 Jan 2024, 10:42 a.m.

GOSH is one of six leading European children’s hospitals that make up the PHEMS project, which will revolutionise how children’s health data is managed and used across Europe and advance research and innovation in healthcare for children.

Ground-breaking study that utilises mRNA technology shows hope for rare disease treatment

18 Jan 2024, 11 a.m.

Explore ground-breaking research at the intersection of Covid-19 vaccine technology and rare disease therapy.

A young boy smiles widely at the camera from a car seat. He's wearing a straw summer hat and summer clothes. In the background you can see a blurry picture of a little girl in another car seat

Reducing oxygen levels for children in intensive care will save lives

1 Dec 2023, 11:30 p.m.

A new landmark study led from GOSH has found that reducing oxygen levels for critically ill children on mechanical ventilators in intensive care could save lives

Illustration of healthcare professional using a computer and a child with a cochlear implant. There are numbers leaving the computer that represent data.

GOSH to provide support for AI and Machine Learning as part of new paediatric HealthTech Research Centre

23 Nov 2023, 10 a.m.

GOSH will support the new Child and Young People’s HealthTech Research Centre (HRC), led by Sheffield Children’s Hospital, as leads for AI and Machine Learning.

A young girl with light brown and orange long hair smiling. She has medals hanging from red, white and blue ribbon around her neck.

Clinical trial results give new hope for children with rare brain tumours

18 Nov 2023, 8 a.m.

Researchers who are searching for better treatments for an incredibly rare type of brain tumour have published successful results from the latest rounds of clinical trials.

Lab technicians working in a specialist GOSH laboratory, wearing white protective suits and masks and orange gloves.

GOSH receives new MHRA authorisation to manufacture viral vectors

1 Nov 2023, 5 p.m.

GOSH has been granted a Manufacturer's Authorisation Licence for the manufacture of viral vectors, which will accelerate Cell and gene therapies (CGT) clinical trials worldwide and expand the novel treatments that we can offer to our patients.

A selection of images from the 2nd annual NIHR GOSH BRC competition

3rd Annual NIHR GOSH BRC Image Competition - A Moment of Discovery

1 Nov 2023, noon

The Research and Innovation Communications team at GOSH and the NIHR GOSH Biomedical Research invite you to enter our Research and Innovation Showcase: A Moment of Discovery.

Photograph of a digital screen with brain imaging. Text on top reads '5 Years of Digital Innovation: Impact Report'

Over 300 innovative projects completed since the launch of GOSH DRIVE in 2018

25 Sep 2023, 1:09 p.m.

The Data Research, Innovation and Virtual Environments (DRIVE) unit at GOSH was launched five years ago. Our new report explains how this first-of-its-kind unit has led to improvements in research and innovation, and care for children and young people.

Aditi in a hospital room, sat on our hospital bed at GOSH. She wears a bright yellow top, and has a nasogastric (NG) feeding tube and bright pink glasses and a purple monster hat. She smiles just off camera.

GOSH patient first in the UK to receive improved kidney transplant

22 Sep 2023, 10 a.m.

Eight-year-old Aditi is the first child in the UK and on the NHS to be taken off immunosuppressants just one-month after kidney transplant at Great Ormond Street Hospital (GOSH).

A crowd of people, focusing on 3 women in the middle distance, in conversation, smiling. In the foreground a woman wearing a headscarf looks down

A showcase of research

7 Sep 2023, 5:12 p.m.

This summer saw the return of the NIHR GOSH BRC showcase.

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Steps forward in gene therapy for hearing loss linked to rare disease

29 Aug 2023, 3 p.m.

An international team led by researchers at GOSH, UCL and the NIHR GOSH BRC have developed in mice a gene therapy that significantly reduces the hearing loss associated with Norrie disease.

A close up photograph of multiple pippets and test tubes.

Global genomic collaboration improves lives and treatment for children with epilepsy

17 Aug 2023, 8 a.m.

An international research collaboration, including GOSH and our research partner UCL Institute of Child Health, has shown that a technique known as rapid genome sequencing can provide a diagnosis for 43 per cent of children with unexplained epilepsy.

Four people stand in a line, smiling at the camera with their arms around each other. On the far left stands a nurse., Jan, wearing a blue uniform and black framed square glasses. She stands next to a Austin's Mum, Louise, who has a dark brown bob wearing jeans and a black jumper. Austin stands next to his mum, wearing a black hoodie and black trousers. Finally, Danielle, another nurse, stands on the far right with blonde hair in a ponytail and a blue nurses uniform

Unlocking the mystery of long-lasting cancer treatment

6 Jul 2023, 8 a.m.

Researchers from across GOSH, UCL GOS ICH and the Wellcome Sanger Institute have published new insights that explain why some children have a longer remission than others after having cutting-edge CAR T-cell therapy for leukaemia.

A young girl in a blue t-shirt is sitting down with her back to the camera, stretching sideways to shake the hand of a man in a white shirt who is bending down to meet her. She is smiling and so is he.

GOSH receives over £3.5m for research and innovation

28 Jun 2023, 11:31 a.m.

GOSH has been awarded over £3.5m by the NIHR for vital research and innovation equipment that will help to improve treatments for children

A young boy wears safety goggles, a white lab coat and very large blue protective gloves. He holds onto and looks down a mini-microscope while sat on a lime green chair.

Celebrating International Clinical Trials Day with our patients and families

21 Jun 2023, 11 a.m.

On 19 May we enjoyed welcoming patients, their families and GOSH staff, including GOSH nursery to the Lagoon to celebrate International Clinical Trials Day as well as the NIHR “Be Part of Research" campaign.

Blue stem cells with purple dots growing with tree like branches.

How 3D ‘bio-printing’ can shape mini-organs

9 Jun 2023, 4 p.m.

Scientists have shown for the first time how 3D printing can be achieved inside ‘mini-organs’ growing in hydrogels - controlling their shape, activity, and even forcing tissue to grow into ‘moulds’.