Dr Wendy Heywood awarded investigator initiated research proposal from Shire Pharmaceuticals
28 Jun 2016, 2:01 p.m.
Following NIHR Great Ormond Street BRC support, which led to the creation of a high-throughput targeted proteomic urine test, Dr Wendy Heywood has been awarded an industry investigator initiated award from Shire Pharmaceuticals.
Drug for Duchenne Muscular Dystrophy shows promise in clinical trial
21 Aug 2017, 12:02 p.m.
An international clinical trial has found that the drug ataluren can improve mobility for children with a severe form of Duchenne muscular dystrophy (DMD).
Film celebrates success of Biomedical Research Centres set up by outgoing UK Chief Medical Officer
14 Oct 2019, 11:37 a.m.
NHS patients who have taken part in clinical trials have expressed their gratitude to researchers in a film celebrating the work of the National Institute for Health Research (NIHR) Biomedical Research Centres (BRCs), including GOSH BRC, to mark the retir
First drug to reduce fever flares in children with recurrent fever conditions
17 Aug 2018, 12:02 p.m.
Injections of the drug canakinumab significantly reduced the number of fever episodes in children with three different types of recurrent fever conditions, in an international trial led at GOSH by Professor Paul Brogan.
Funding boost to develop novel therapy for rare metabolic condition
1 Apr 2019, 10:19 a.m.
GOSH and UCL Great Ormond Street Institute of Child Health (ICH) researchers Professor Paul Gissen and Dr Julien Baruteau will be part of a new collaboration with Evox Therapeutics that aims to develop a new therapy for the life threatening metabolic cond
Funding to develop immunotherapy for childhood sarcomas
18 Dec 2015, 1:01 p.m.
Biomedical Research Centre (BRC) supported Professor John Anderson has been awarded funding from Children with Cancer UK to investigate new immunotherapy approaches for childhood sarcomas.
Funding provided to develop new therapy for acute liver failure
9 Sep 2015, 4:50 p.m.
BRC-supported researcher Dr Kevin Mills has been awarded funding from the NIHR to investigate the regenerative ability of the liver following acute liver failure (ALF). If successful, the team hope that their research will lead to a novel therapy that cou
Two multi-million-pound research grants will fund a pioneering new programme of research aimed at understanding and tackling Parkinson’s disease, including vital genetic investigations at the UCL Great Ormond Street Institute of Child Health (ICH).
Gene therapy treatment manufactured at GOSH and ICH used to treat world's first patient with life limiting genetic condition, MPSIIIA
28 May 2019, noon
A two-year old patient at the Royal Manchester Children’s Hospital (RMCH) is the first in the world to receive a pioneering new gene therapy treatment for the rare and life-limiting genetic condition, Mucopolysaccharidosis IIIA (MPSIIIA). The treatment wa
Gene therapy trial for patients with Fanconi anaemia to open at GOSH
22 Mar 2016, 5:24 p.m.
A clinical trial is to open at Great Ormond Street Hospital (GOSH) that will test the use of gene therapy during transplantation for the treatment of young people with Fanconi anaemia.
Last weekend, we opened our doors to over 300 visitors for the annual Family Fun Day hosted by the National Institute for Health Research (NIHR) Great Ormond Street Hospital (GOSH) Biomedical Research Centre (BRC).
GOSH awarded £37 million funding to carry out pioneering paediatric research
14 Sep 2016, 5:39 p.m.
The NIHR Great Ormond Street Biomedical Research Centre (BRC) has been awarded £37 million in funding to drive forward translational research into rare diseases in children. The Centre is the only one of its kind in the UK dedicated to paediatric research
GOSH research brings Duchenne muscular dystrophy drug one step closer to UK patients
5 Mar 2020, 9:30 p.m.
A drug that ‘skips over’ a genetic fault responsible for the fatal muscle-wasting condition Duchenne muscular dystrophy (DMD) has shown promising results in an international trial led by Great Ormond Street Hospital (GOSH).
Professors Bobby Gasper and Adrian Thrasher, both members of the BRC senior management team, have been awarded the UCL Business Award, in recognition of their work on the spin-out company Orchard Therapeutics.
GOSH set to take part in world first human challenge study to find a COVID-19 vaccine
27 Oct 2020, 11:02 a.m.
National Institute of Health Research (NIHR) Great Ormond Street Hospital Biomedical Research Centre is set to play a crucial role in a new study exploring the possibility of running the first human challenge study to find a vaccine for COVID-19.
High throughput screening identifies the genetic cause underlying a rare disease in a large nationwide cohort
18 Dec 2015, 1:20 p.m.
A collaborative study between ICH and the Turkish Pediatric Endocrinology Society has used high throughput DNA analysis to identify the genetic cause of primary adrenal insufficiency in more than 80% of affected children.
