BRC news

Meet physiotherapist Lesley Katchburian who cares for Cora in episode four of Paul O’Grady’s Little Heroes. Lesley, who is Lead Clinical Specialist Physiotherapist for Botulinum Toxin Services in Neurodisability at GOSH, explains why botulinum toxin can be helpful for children with cerebral palsy and why research is so important. 

The NIHR GOSH BRC last month hosted an inaugural medical devices workshop, in partnership with the UCL Institute of Healthcare Engineering. 

Patients at Great Ormond Street Hospital (GOSH) and across England are set to receive treatment for the rare nervous system condition Battens Disease, following a deal between the NHS and manufacturer Biomarin. The drug, which is called cerliponase alfa or Brineura, has been approved by the NHS following successful clinical trials at GOSH in collaboration with other centres from across the world. 

​Joe, aged 15, who features on Paul O’Grady’s Little Heroes, is being treated at GOSH for Marfan Syndrome, a genetic disorder that affects the body’s connective tissue, which plays an important role in helping the body grow and develop properly. Joe has an associated heart condition and required surgery to replace his aorta, the body’s main artery. 

The medical and research team involved in his care share how they have used pioneering 3D Heart Modelling and Virtual Reality to aid understanding of his heart condition ahead of surgery. 

Artificial intelligence (AI) is increasingly being used to improve our everyday lives and, at GOSH we’re proud to be leading the way in applying this sophisticated technology to healthcare research. Dr Valeria Ricotti shares how we've been using AI to understand more about duchenne muscular dystrophy (DMD). 

A clinical trial to investigate a novel CAR T-cell therapy, designed to target cancer cells more quickly and cause less side effects, has shown very promising results for children with previously incurable acute lymphoblastic leukaemia (ALL). 

A survey of young people, their friends, family and healthcare professionals has identified the most urgent research priorities for young people with cancer.

GOSH researchers have developed the first ever tool to identify children at risk of sudden death from a rare heart condition called hypertrophic cardiomyopathy (HCM).