He has a special interest in common and rare forms of diabetes, endocrine tumours and growth failure.
Qualifications and training
MBChB (with Honours), MRCP, MSc, MD with commendation, FRCPCH.
Dr Amin trained at Leeds University where he received an honours degree in medicine (1991).
He trained in paediatric medicine in London (1996) before specializing in paediatric endocrinology and diabetes in London and Oxford (2004).
He was awarded an MD with commendation for research undertaken at Cambridge on the subject of the hormonal determinants of microvascular disease in type 1 diabetes (2006). Subsequently, he was appointed as a Consultant in paediatric endocrinology and diabetes, initially at the Royal Manchester Children’s Hospital (2005) and then at St Barts and the London Hospitals (2010). He started as a consultant and honorary senior lecturer at GOSH and ICH in 2012.
Dr Amin is a member of the British Society for Paediatric Endocrinology and Diabetes (BSPED) and the European Society for Paediatric Endocrinology. He is a member of the National Diabetes Audit Dataset Working Group and the BSPED Clinical Trials Study Group and numerous other study and research groups. He is the diabetes officer for BSPED. He has sat on the scoping group to update the NICE Guidance for Diabetes in Pregnancy.
Dr Amin has been invited to speak at a number of national and international meetings, and has received numerous awards during his undergraduate and postgraduate training.
Pathogenesis of Type 1 Diabetes
- Measurement of Serum Insulin methylated DNA as a Marker of Beta-Cell Death.
- In-vivo Imaging of Beta-cells and Insulinitis
Complications of Diabetes
- The University College London Investigation of Diabetes (UCLID) Study
- Developmental of a Cardiovascular Disease Risk Algorithm for Type 1 Diabetes
- Patient Reported Experience Measures and Acute and Chronic Outcomes for Children with Diabetes
- HbA1c tracking and Diabetes Complications
- Incidence of Diabetic Ketoacidosis in Children in the UK and Europe
- Vitamin E metabolites in the Development of Cardiovascular Disease in Type 1 Diabetes
- Development of Other Biomarkers of Diabetes Complications
- Effect of Ethnicity in Type 1 Diabetes
- Brain Imaging in Type 1 Diabetes
- The Epidemiology of Diabetic Ketoacidosis in the UK
- Inequitable Service Delivery for Type 1 Diabetes in the UK
- Outcomes for Somali Children Living with Diabetes in the UK
- Paediatric HOMA
1. Kendall D, Vail A, Amin R, Barrett T, Dimitri P, Ivison F, et al. Metformin in obese children and adolescents: the MOCA trial. The Journal of clinical endocrinology and metabolism. 2013;98(1):322-9. Epub 2012/11/24.
2. Dias RP, Brown F, Wyatt C, Cheema S, Allgrove J, Amin R. The effect of insulin intensification in children and young persons with Type 1 diabetes differs in relation to ethnic group; a prospective observational study. Diabetic medicine : a journal of the British Diabetic Association. 2012. Epub 2012/09/25.
3. Hine P, Senniappan S, Sankar V, Amin R. Deprivation impedes success of insulin intensification in children and adolescents with Type 1 diabetes; longitudinal linear mixed modelling of a retrospective observational cohort. Diabetic medicine : a journal of the British Diabetic Association. 2011;28(3):338-44.
4. Puttha R, Cooke D, Subbarayan A, Odeka E, Ariyawansa I, Bone M, et al. Low dose (0.05 units/kg/h) is comparable with standard dose (0.1 units/kg/h) intravenous insulin infusion for the initial treatment of diabetic ketoacidosis in children with type 1 diabetes-an observational study. Pediatric diabetes. 2010;11(1):12-7.
5. Amin R, Widmer B, Prevost AT, Schwarze P, Cooper J, Edge J, et al. Risk of microalbuminuria and progression to macroalbuminuria in a cohort with childhood onset type 1 diabetes: prospective observational study. Bmj. 2008;336(7646):697-701.
6. Amin R, Frystyk J, Ong K, Dalton RN, Flyvbjerg A, Dunger DB. The development of microalbuminuria is associated with raised longitudinal adiponectin levels in female but not male adolescent patients with type 1 diabetes. Diabetologia. 2008;51(9):1707-13.
Dr Amin coordinates under and postgraduate education at the endocrine department at GOSH. He has supervised several specialist registrars, medical students and visiting clinicians.
Department of Endocrinology
Great Ormond Street Hospital NHS Foundation Trust
Secretary Tel: 020 7405 9200 ext 8519
Fax: 020 7813 8258