Conditions treated at the GOSH Comprehensive Care Centre for Bleeding and Thrombosis

The Comprehensive Care Centre for Bleeding and Thrombosis (formerly known as Haemophilia Comprehensive Care Centre) at Great Ormond Street Hospital treats a range of conditions. These include:

• Haemophilia - an inherited bleeding disorder caused by deficiency of either factor VIII (Haemophilia A) or IX (Haemophilia B). It mainly affects boys although female carriers may also experience bleeding problems.
• Von Willebrand disease
• Fibrinogen (Factor I) deficiency
• Prothrombin (Factor II) deficiency
• Factor V deficiency
• Factor VII deficiency
• Factor X deficiency
• Factor XI deficiency
• Factor XIII deficiency
• Platelet disorders including:
  • Bernard Soulier disease
  • Glanzmann’s thrombasthenia
  • Hermansky Pudlak syndrome
  • Jacobsen syndrome
  • Lowe syndrome
  • Platelet release and storage pool defects
  • Thrombocytopenia with absent radius (TAR) syndrome
  • Thrombotic thrombocytopenic purpura (TTP)