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Encephalocele

An encephalocele is a rare congenital (present at birth) type of neural tube defect where part of the skull has not formed properly so a portion of brain tissue and associated structures are outside the skull. The protruding sac may be covered with skin o

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About the Dubowitz Neuromuscular Centre

The Dubowitz Neuromuscular Centre (DNC) at Great Ormond Street Hospital (GOSH) is a leading clinical and research centre specialising in neuromuscular disorders affecting children. The DNC provides clinical assessment, diagnostic services and advice on tr

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Matthew Shaw, GOSH Medical Director

Great Ormond Street Hospital appoints new Medical Director

14 Dec 2017, 6:48 p.m.

The world-renowned children’s hospital has appointed Matthew Shaw to take over the position of Medical Director at the start of the next financial year.

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New GOSH hospital CEO Mat Shaw

GOSH appoints new chief executive

29 Nov 2018, 10:42 a.m.

Matthew Shaw has been appointed as Chief Executive at Great Ormond Street Hospital for Children NHS Foundation Trust (GOSH) after being the Medical Director at the Trust.

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Acute neurology admission criteria

This is a list of patient diagnoses which are admitted to Great Ormond Street Hospital (GOSH) by our Acute Neurology team, the timeframe in which they should be treated, and their estimated length of stay (LoS).

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Neuromuscular admission criteria

This is a list of patient diagnoses which are admitted to Great Ormond Street Hospital (GOSH) by our Neuromuscular team, the timeframe in which they should be treated and their estimated length of stay (LoS).

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Cutis aplasia

Cutis aplasia means ‘missing skin’ and is a congenital (present at birth) condition where a section of skin, usually on the scalp, is missing. This page explains the condition called cutis aplasia, what causes it and how it can be treated. It also outline

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Headshot of Professor Darren Hargrave.

Professor Darren Hargrave appointed NIHR Senior Investigator

19 Mar 2025, 2:44 p.m.

We’re delighted to announce that Professor Darren Hargrave has been named as a NIHR Senior Investigator in this year’s prestigious awards list.

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Research services

The research activity of the Dubowitz Neuromuscular Centre is carried out at the Institute of Child Health (ICI) and is directed by Professor Francesco Muntoni.

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Medical Devices Workshop

12 Sep 2019 noon 5 p.m.

12th September 2019

12-5pm

Institute of Child Health

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Hear from our multi-speciality staff

Meet some of our fantastic multi-speciality staff who feature on Paul O'Grady's Little Heroes to learn more about the work they do at GOSH and the care they provide for patients and families. New stories will be added each week!

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Treating and reducing the risk of pressure ulcers after leaving hospital

Our skin is the most important barrier against infection so we need to look after it carefully. Sometimes, for a variety of reasons, people who are unwell develop pressure ulcers. At Great Ormond Street Hospital (GOSH), we recognise that children can deve

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Black line drawing of a child smiling, with the words "NHS Great Ormond Street Hospital for Children NHS Foundation Trust", written in blue and black text.

Inquest of Amy Allan - updated statement

17 Jan 2020, 11:03 a.m.

Following the inquest into the death of Amy Allan in September 2019 and the subsequent Preventing Future Deaths report given to Great Ormond Street Hospital by the Coroner, Chief Executive Matthew Shaw would like to provide an update on the work that has

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Crouzon syndrome

Crouzon syndrome is the most common type of complex craniosynostosis. It is named after the doctor who first described it in the early 20th century. This page from Great Ormond Street Hospital (GOSH) explains the causes, symptoms and treatment of Crouzon

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Inherited White Matter Disorders (IWMD)

Inherited White Matter Disorders (IWMD), also known as leukodystrophies, are rare genetic disorders that primarily affect the white matter of the nervous system (the brain, spinal cord and peripheral nerves).

Many, but not all, IWMDs are progressive …

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A woman at work in a lab, looking into a microscope.

Low myostatin levels linked to lack of success of anti-myostatin drugs for muscle-wasting conditions

30 Nov 2017, 2:04 p.m.

Levels of myostatin, a protein that prevents muscle growth, could influence how well the body responds to anti-myostatin treatments for muscle-wasting conditions such as Duchenne Muscular Dystrophy (DMD). This breakthrough could help predict which patient

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GOSH Trust logo

Inquest of Amy Allan

1 Oct 2019, 4:25 p.m.

Following the inquest into the death of former patient Amy Allan and the subsequent Preventing Future Deaths report given to Great Ormond Street Hospital, Chief Executive Matthew Shaw would like to outline how the hospital is learning from this and what a

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BBC2's Great Ormond Street - Part Four

29 May 2012, 9:52 a.m.

Follow the stories of the Great Ormond Street patients, their families and clinical teams on BBC2 9-10pm.

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Nursing in our Paediatric Intensive Care Unit (PICU)

Approximately 1,200 patients are admitted to our Paediatric Intensive Care Unit (PICU) each year. They are mainly admitted from the North Thames area, but our specialist departments also service the UK and abroad.

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Medical Devices Development Workshop

Have a great starting idea but are unsure of the next steps? Facing a clinical problem that a new device could solve? Or simply curious about the whole translational pathway? Come along to this workshop, on the 12th September 2019, hosted by the UCL Inst

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