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Tissue removed during heart surgery is saving lives of children with no immune system

15 Apr 2017, 2:31 p.m.

In a European first, a little-known gland called the ‘thymus’, some of which is routinely removed during cardiac surgery, has saved the lives of children with a life threatening immunodeficiency condition, complete DiGeorge syndrome (cDGS).

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Tissue removed during heart surgery is saving lives of children with no immune system

15 Apr 2017, 10:30 a.m.

In a European first, a little-known gland called the ‘thymus’, some of which is routinely removed during cardiac surgery, has saved the lives of children with a life threatening immunodeficiency condition, complete DiGeorge syndrome (cDGS).

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BRC central development hub

NIHR Great Ormond Street Hospital Biomedical Research Centre

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GOSH patient with a research nurse

​GOSH ranked fourth in North Thames region for clinical trial activity

2 Aug 2017, 1:33 p.m.

Great Ormond Street Hospital for Children NHS Foundation Trust (GOSH) has been ranked 4th in the North Thames region for number of active clinical research studies in 2016/17, in figures released today by the National Institute for Health Research (NIHR).

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T cell render

Cellular benefits of gene therapy seen decades after treatment

16 Mar 2021, 4:54 p.m.

An international collaboration has shown the beneficial effects of gene therapy can be seen decades after the transplanted blood stem cells have been cleared by the body.

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Earlier ART treatment for children with HIV in Africa leads to stronger immune systems in adulthood

21 Oct 2013, 4:41 p.m.

In a study funded by the Medical Research Council (MRC), the Engineering and Physical Sciences Research Council (EPSRC), the Department for International Development (DFID) and Great Ormond Street Hospital (GOSH) Biomedical Research Centre, researchers ha

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A close up of a pippet and test tubes.

£35 million research boost for GOSH

14 Oct 2022, 10 a.m.

The National Institute for Health and Care Research (NIHR) has announced that the Great Ormond Street Hospital (GOSH) Biomedical Research Centre (NIHR GOSH BRC) is one of 20 centres from across the country to receive 5-years of funding.

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Test tubes on a revolving plate in a lab

The next five years of ground-breaking research

3 Apr 2017, 12:08 p.m.

The National Institute for Health Research (NIHR) Great Ormond Street Hospital Biomedical Research Centre (GOSH BRC) starts its new new five-year funding term today.

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Genetic Code

North Thames recruitment to 100,000 genome project exceptionally strong for rare diseases

14 Dec 2016, 9:41 a.m.

The North Thames Genomic Medicine Centre’s (GMC) has recruited 5,200 genomes to the 100,000 Genomes project for rare diseases, making up around 28% of those recruited nationally.

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Spectratyping

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TRECS analysis

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A thumbnail featuring Lyn in a circle image, against a graphic of two blue circles.

Professor Lyn Chitty made a Dame in New Year's Honours

30 Dec 2022, 10:30 p.m.

Professor Lyn Chitty has been made a Dame in the 2023 New Year’s Honours List.

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About the Children's Epilepsy Surgery Service (CESS)

Since 2012, the NHS has made epilepsy surgery a nationally commissioned service and in England there are four centres designated as part of the Children’s Epilepsy Surgery Service (CESS).

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Tissue engineering and regenerative medicine

Tissue engineering and regenerative medicine

Theme Leads: Professor Jane Sowden and Professor Paolo De Coppi

Theme Deputy Leads: Dr Conor McCann and Dr Stavros Loukogeorgakis

Junior Faculty Representatives: Dr Jennie Chandler and Dr Giovanni Giobbe

Research Theme Manager: Dr Valerija Karaluka

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GOSH awarded £37 million funding to carry out pioneering paediatric research

14 Sep 2016, 5:39 p.m.

The NIHR Great Ormond Street Biomedical Research Centre (BRC) has been awarded £37 million in funding to drive forward translational research into rare diseases in children. The Centre is the only one of its kind in the UK dedicated to paediatric research

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A young boy with brown hair sat on a seesaw. He is smiling and wearing a blue striped top.

NHS genetic testing gives ‘power’ to families with rare conditions

2 Dec 2025, 9 a.m.

A new study has shown that whole genome sequencing, now offered as part of NHS care, allows children with rare conditions to access the right care faster.

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A Crowd of people talk in a busy room - the central focus shows a woman smiling and talking with a colleague who has their back to the camera

Celebrating research that transforms lives

27 Oct 2025, 3:23 p.m.

The 2025 NIHR GOSH BRC Showcase recently celebrated some incredible progress made in paediatric research.

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A woman with short brown hair is smiling.

GOSH Consultant, Dr Emma Clement, joins the North Thames Genomic Medicine Service

12 Jan 2026, 10:56 a.m.

Dr Emma Clement has joined the NT GMS as Deputy Medical Director.

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Meet the Nephrology team

The clinicians of the Nephrology Department provide all aspects of inpatient and outpatient paediatric nephrology care including highly specialised services.

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Siblings Lucy and Thomas stood outside of the Great Ormond Street Hospital entrance. The entrance doors are colourfully decorated and the siblings are stood in front of floor displays.

Family with rare condition are recipients of 500th Heart Transplant at GOSH

24 Jul 2023, 9 a.m.

A team of more than 50 specialists from across the country pulled together to help carry out the 500th heart transplant at Great Ormond Street Hospital (GOSH). Thomas, Lucy, their mum, Khristine and oldest sister Bethany shared their story on the BBC Brea

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