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New Director Designate announced for NIHR GOSH Biomedical Research Centre

5 Nov 2025, 3:44 p.m.

Professor Paul Gissen has been announced as the Director Designate of the NIHR GOSH Biomedical Research Centre.

Study linking data from 85% of children in England compares rare cardiac risks post-COVID vs vaccination

5 Nov 2025, 9:30 a.m.

A major study which analysed anonymised health records from over 14 million children in England has shown that rare heart and inflammatory issues were more likely - and lasted longer - after COVID-19 infection than after vaccination.

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Celebrating research that transforms lives

27 Oct 2025, 3:23 p.m.

The 2025 NIHR GOSH BRC Showcase recently celebrated some incredible progress made in paediatric research.

A boy stood with his mum, dad, two brothers and sisters

Landmark gene therapy study shows safety for children

16 Oct 2025, 9:54 a.m.

Results from the largest cohort of children who received a gene therapy for a rare immunodeficiency condition have shown the long-term safety and efficacy of the curative treatment.

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New study pinpoints why some transplanted kidneys are rejected

17 Sep 2025, 8:44 p.m.

Researchers at University College London (UCL), the Wellcome Sanger Institute and the University of Cambridge combined technology that determines the genetic or RNA sequence of individual cells with powerful 3D imaging to look at lymphatic vessels

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Scientists discover clues to help children with rare muscle disease

8 Sep 2025, 4:20 p.m.

New ground-breaking research by experts at Great Ormond Street Hospital (GOSH) and University College London (UCL) has led to an exciting discovery that could help children with the rare muscle disease, juvenile dermatomyositis (JDM).

two consultant doctors sat facing each other having conversation with screens behind them

GOSH-led trial of AI-scribe technology shows ‘transformative’ benefits for patients and clinicians across London

4 Sep 2025, 6 a.m.

A major GOSH-led study has found that AI-scribing technology can significantly reduce clinician workload while improving patient care

A colorful illustration of three small primates—a bush baby (galago), a tamarin monkey, and a mouse lemur—posed playfully against a vibrant background. Each animal is depicted with friendly, expressive features to highlight their role in evolutionary research.

What do bush babies, tamarin monkeys, and mouse lemurs have that humans don’t?

28 Aug 2025, 10:41 a.m.

GOSH imaging researchers have worked with teams in Harvard in the USA to work out how and when our pelvises developed to be different from other animals.

A small baby with a breathing tube lies in a hospital incubator holding a hand.

Nanodiamonds and hormones used in rare condition to promote lung growth

27 Aug 2025, 9 a.m.

An international research team led by GOSH, UCL and KU Leuven in Belgium, is using 3D-printing and nanodiamonds, to design treatments that could help babies repair their damaged lungs in the womb.

13 staff members, some wearing uniform and some wearing their own clothes, stood in front of the sign for the Royal Ear Hospital the

New national registry for inherited hearing loss

26 Aug 2025, 2:20 p.m.

A new national registry is helping researchers understand more about inherited hearing loss – and could help bring about new treatments.

Boy with brown hair stood infront of a white car holding up a piece of paper driving license

Teenager off to university after life-changing gene therapy

18 Aug 2025, 6 a.m.

A teenager with a rare, life-limiting genetic condition is off to university after receiving a gene therapy that changed his life.

A boy stood in front of mountains wearing a black baseball cap and smiling.

Stem cell treatment can improve rare skin condition in children

15 Aug 2025, 9:46 a.m.

Children with a rare skin condition have found their symptoms have improved through taking part in the largest clinical trial of its kind, led by clinicians at Great Ormond Street Hospital for Children (GOSH).

Young people donate tissue samples to unlock mysteries of arthritis

2 Jul 2025, 9:49 a.m.

A new groundbreaking study led by researchers at the University of Birmingham, Great Ormond Street Hospital, University College London and Birmingham Children’s Hospital has revealed important clues into what is driving arthritis in children.

Toddler doing well after receiving newest gene therapy available on NHS

25 Jun 2025, 9:23 a.m.

A toddler with a life-limiting and life-threatening rare disease is the youngest to be treated with the newest gene therapy available on the NHS at GOSH.

Researcher holding a pipette dropping liquid into a test tube

Genes may help to predict which children will respond well to arthritis treatment

16 Jun 2025, 4:37 p.m.

A team of researchers at Great Ormond Street Hospital (GOSH) and University College London (UCL) have identified a set of genes that could be used to help doctors predict which children will respond well to treatment for juvenile idiopathic arthritis.

Making it easier to invest in frontline care

12 Jun 2025, 4:53 p.m.

GOSH and UCL have signed a landmark agreement to simplify the commercialisation of any joint research and innovation and ensure any financial proceeds are shared equally.

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Patients and public help create multilingual resources for expectant parents

4 Jun 2025, 3:21 p.m.

A group of clinicians and researchers at GOSH have developed information about a test offered in pregnancy called prenatal sequencing in the UK’s 12 most common languages.

GOSH Arts dance with a child and their parent

NIHR GOSH CRF celebrates International Clinical Trials Day

21 May 2025, 6:09 p.m.

On Tuesday 20 May we celebrated International Clinical Trials Day in NIHR GOSH Clinical Research Facility (CRF).

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New 'Secure Data Environment' joint offering from GOSH and Aridhia to accelerate clinical research and healthcare innovation

21 May 2025, 2:35 p.m.

We are expanding our partnership with Aridhia to include an offer to external partners.

New VR game to help children rehabilitate after brain tumour treatment

15 May 2025, 1:28 p.m.

The National Institute for Health and Care Research Great Ormond Street Hospital Biomedical Research Centre (NIHR GOSH BRC) is working with partners to develop a new virtual reality (VR) game.