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Human nasal cells cultured in a petri dish

New study finds that nasal cells protect against Covid-19 in children

18 Apr 2024, 9:20 a.m.

New research shows that children are less likely than adults to develop severe COVID because cells in their nose are better at fighting off the virus.

New plan announced to get more children access to gene therapy treatments

9 Apr 2024, 9 a.m.

Great Ormond Street Hospital (GOSH) has announced plans to revolutionise how children living with a rare disease can gain access to life-changing treatments.

First-of-its-kind study into the Ketogenic diet

2 Apr 2024, 10 a.m.

A ketogenic diet, which is low in carbohydrates and high in fat, shows promise as an alternative treatment option for infants with drug-resistant epilepsy.

Adult helping a child in goggles with a pipette

Raising awareness on Rare Disease Day

8 Mar 2024, 12:04 p.m.

To celebrate Rare Disease Day we invited patients and their families to try out 13 different hands-on and interactive fun and educational science and research activities for children and adults.

a mis-shapen ball of red circles, surrounded by blue filaments on a black background

Stem cells collected in late pregnancy herald advances in prenatal medicine

4 Mar 2024, 4 p.m.

A new pioneering approach, developed by researchers at UCL and Great Ormond Street Hospital means human development can be observed in late pregnancy for the first time

Senior research associate Giovanni Giuseppe Giobbe, Marta Gazzaneo, Lucy Holland and Giada Benedetti standing together in the ZCR

A moment of discovery: extraordinary images showcase research at GOSH

29 Feb 2024, 9 a.m.

A vibrant image helping researchers' study gastrointestinal diseases and their potential treatments has been crowned the winner of the 3rd annual National Institute for Health and Care Research Great Ormond Street Hospital Biomedical Research Centre (NIHR

Staff working at cell and Gene therapy clean room at the ZCR

172 years of leaps in medical science at GOSH

14 Feb 2024, 6 a.m.

Today on Wednesday 14 February, GOSH is celebrating its 172nd birthday. With 2024 being a leap year, we wanted to look back at some of the leaps that we have made in medical science over the past 172 years

Child with Norrie Disease playing in a parachute with two adults

Patients, families, clinicians and researchers learn together on rare blinding condition

18 Jan 2024, 1:52 p.m.

Last December, the Norrie Disease conference took place at University College London, Great Ormond Street Institute of Child Health, organised by the Norrie Disease Foundation and Professor Jane Sowden’s research group.

Blue background with data sequences and code in vibrant green colour crossing over in different directions

GOSH collaborating in pioneering PHEMS project to revolutionise use of health data across Europe

18 Jan 2024, 10:42 a.m.

GOSH is one of six leading European children’s hospitals that make up the PHEMS project, which will revolutionise how children’s health data is managed and used across Europe and advance research and innovation in healthcare for children.

Ground-breaking study that utilises mRNA technology shows hope for rare disease treatment

18 Jan 2024, 11 a.m.

Explore ground-breaking research at the intersection of Covid-19 vaccine technology and rare disease therapy.

A young boy smiles widely at the camera from a car seat. He's wearing a straw summer hat and summer clothes. In the background you can see a blurry picture of a little girl in another car seat

Reducing oxygen levels for children in intensive care will save lives

1 Dec 2023, 11:30 p.m.

A new landmark study led from GOSH has found that reducing oxygen levels for critically ill children on mechanical ventilators in intensive care could save lives

Illustration of healthcare professional using a computer and a child with a cochlear implant. There are numbers leaving the computer that represent data.

GOSH to provide support for AI and Machine Learning as part of new paediatric HealthTech Research Centre

23 Nov 2023, 10 a.m.

GOSH will support the new Child and Young People’s HealthTech Research Centre (HRC), led by Sheffield Children’s Hospital, as leads for AI and Machine Learning.

A young girl with light brown and orange long hair smiling. She has medals hanging from red, white and blue ribbon around her neck.

Clinical trial results give new hope for children with rare brain tumours

18 Nov 2023, 8 a.m.

Researchers who are searching for better treatments for an incredibly rare type of brain tumour have published successful results from the latest rounds of clinical trials.

Lab technicians working in a specialist GOSH laboratory, wearing white protective suits and masks and orange gloves.

GOSH receives new MHRA authorisation to manufacture viral vectors

1 Nov 2023, 5 p.m.

GOSH has been granted a Manufacturer's Authorisation Licence for the manufacture of viral vectors, which will accelerate Cell and gene therapies (CGT) clinical trials worldwide and expand the novel treatments that we can offer to our patients.

A selection of images from the 2nd annual NIHR GOSH BRC competition

3rd Annual NIHR GOSH BRC Image Competition - A Moment of Discovery

1 Nov 2023, noon

The Research and Innovation Communications team at GOSH and the NIHR GOSH Biomedical Research invite you to enter our Research and Innovation Showcase: A Moment of Discovery.

Photograph of a digital screen with brain imaging. Text on top reads '5 Years of Digital Innovation: Impact Report'

Over 300 innovative projects completed since the launch of GOSH DRIVE in 2018

25 Sep 2023, 1:09 p.m.

The Data Research, Innovation and Virtual Environments (DRIVE) unit at GOSH was launched five years ago. Our new report explains how this first-of-its-kind unit has led to improvements in research and innovation, and care for children and young people.

Aditi in a hospital room, sat on our hospital bed at GOSH. She wears a bright yellow top, and has a nasogastric (NG) feeding tube and bright pink glasses and a purple monster hat. She smiles just off camera.

GOSH patient first in the UK to receive improved kidney transplant

22 Sep 2023, 10 a.m.

Eight-year-old Aditi is the first child in the UK and on the NHS to be taken off immunosuppressants just one-month after kidney transplant at Great Ormond Street Hospital (GOSH).

A crowd of people, focusing on 3 women in the middle distance, in conversation, smiling. In the foreground a woman wearing a headscarf looks down

A showcase of research

7 Sep 2023, 5:12 p.m.

This summer saw the return of the NIHR GOSH BRC showcase.

A tree like structure made up of fluorescent blue, green and pink dots.

Steps forward in gene therapy for hearing loss linked to rare disease

29 Aug 2023, 3 p.m.

An international team led by researchers at GOSH, UCL and the NIHR GOSH BRC have developed in mice a gene therapy that significantly reduces the hearing loss associated with Norrie disease.

A close up photograph of multiple pippets and test tubes.

Global genomic collaboration improves lives and treatment for children with epilepsy

17 Aug 2023, 8 a.m.

An international research collaboration, including GOSH and our research partner UCL Institute of Child Health, has shown that a technique known as rapid genome sequencing can provide a diagnosis for 43 per cent of children with unexplained epilepsy.