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A lady in a wheelchair wearing. She is surrounded by six men and women, and a young girl who wearing a blue top.

Landmark decision to screen for spinal muscular atrophy at birth

16 Jul 2026, 3:05 p.m.

Great Ormond Street Hospital (GOSH) is delighted at the announcement that newborn babies in England will be offered screening for spinal muscular atrophy (SMA) through the newborn blood spot, or "heel prick", test programme.

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From complex science to clear communication

2 Jul 2026, 11:03 a.m.

Across multiple projects at GOSH, patients, families and young people are playing a vital role in transforming how research is communicated

a close-up view of several adjustable laboratory pipettes in a holder, with lab containers in the background.

Gene therapy successfully treats deadly childhood liver disease in mice

29 Jun 2026, 11:16 a.m.

Researchers at GOSH and UCL have used a new gene therapy to successfully treat a deadly childhood liver disease in mice.

Three people in white lab coats stand in a modern laboratory, viewed through a glass wall, facing a long bench lined with automated equipment, monitors, bottles, and pipetting machines.

World-first gene therapy to target devastating rare immune disorder

29 Jun 2026, 11:16 a.m.

A first-of-its-kind gene therapy to treat people with CTLA-4 insufficiency is being advanced through a collaboration supported by LifeArc, and developed by scientists at UCL, with manufacturing support from NHS Blood and Transplant and GOSH.

A view from above of adult hands playing with some scientific models and the top of a child's head. The child has bright white hair and is wearing a lab coat. You can't see their faces

Shaping better research from the start

22 Jun 2026, 4:12 p.m.

At GOSH, patient and public involvement is helping researchers to ask the right question, right from the start.

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8 years of advancing care through data and innovation

17 Jun 2026, 11:32 a.m.

We have published a new booklet showcasing how our Data Research, Innovation and Virtual Environments (DRIVE) unit is using data and technology to transform care for children and young people at Great Ormond Street Hospital (GOSH).

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UK-wide excellence in paediatrics

15 Jun 2026, 2:42 p.m.

Through the Paediatric Excellence Initiative, the NIHR GOSH Biomedical Research Centre is building a connected, collaborative UK-wide system to accelerate paediatric research.

Image of an MRI result displaying the front and side of a skull in black and white

Researchers identify brain network linked to deadliest childhood brain cancer

15 Jun 2026, 2:25 p.m.

Researchers at GOSH and University College London have identified a human brain network associated with survival in children with diffuse midline glioma, the deadliest childhood brain cancer.

A woman in glasses smiles broadly at the camera while holding up a box with a large silver medal inside.

Professor Jugnoo Rahi awarded prestigious Bowman Medal by the Royal College of Ophthalmologists

10 Jun 2026, 11:41 a.m.

The Bowman Medal is the most senior honour bestowed by the College.

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Professor Helen Cross elected to the Academy of Medical Sciences

8 Jun 2026, 5:39 p.m.

Professor Helen Cross, Paediatric Neurology Consultant at GOSH and Director of the UCL Great Ormond Street Institute of Child Health, has been elected to the prestigious Academy of Medical Sciences.

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Spotlight on our Research Co-ordinators

13 May 2026, 3:12 p.m.

Meet the staff who keep clinical trials on track, ensure the data is up-to-date, that rules are followed and families get their agreed upon support.

Fluorescent microscopic image showing a dense layer of brightly coloured cells, with blue and yellow nuclei surrounded by an intricate network of red and green cell borders

Better understanding leukaemia for children with down syndrome

7 May 2026, 2:16 p.m.

Researchers have mapped the evolution of a type of leukaemia that is exclusive to children with Down syndrome and may have identified an overarching weakness in the cancer's genetic makeup.

Patient wearing jeans and a t-shirt holding a birthday balloon and 10 balloon

Gentler treatment eliminates early deaths for children with relapsed leukaemia

30 Apr 2026, 9:58 a.m.

A groundbreaking national study led by clinicians at Great Ormond Street Hospital (GOSH) has shown that children and young people with relapsed acute lymphoblastic leukaemia (ALL) can be treated safely with significantly less intensive chemotherapy.

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NHS eye gene therapy restores Saffie's sight

22 Apr 2026, 7:30 p.m.

Saffie has had her sight restored thanks to life-changing eye gene therapy for rare blindness at GOSH

Four people wearing lab coats using lab equipment

£3M study led by patient voices targets pain in inflammatory arthritis

21 Apr 2026, 5:07 p.m.

A new £3 million research programme involving Great Ormond Street Hospital and University College London researchers aims to tackle one of the largest unmet clinical needs in inflammatory arthritis – pain reduction.

large group of roughly 50 adults gathered in a bright white room with some sat in chairs, smiling at camera.

GOSH joins European health leaders to shape the future of paediatric data sharing

9 Apr 2026, noon

More than 50 clinicians, data scientists, digital health innovators and industry leaders came together in Barcelona last month to tackle one of the biggest challenges in paediatric healthcare: how to share health data safely across borders to improve care

A young boy smiles broadly at the camera

Engineered tissue offers hope for children born with ‘missing’ food pipe

20 Mar 2026, 10 a.m.

Scientists from Great Ormond Street Hospital (GOSH) and University College London (UCL) have created the first lab‑grown oesophagus - the food pipe - shown to safely replace a full section of the organ and restore normal function, including swallowing, in

A woman in a navy blue nurses uniform smiles broadly at a group of children in white lab coats

GOSH celebrates Rare Disease Day 2026 with local community

16 Mar 2026, 11:25 a.m.

GOSH specialises in rare disease research and to celebrate, we recently invited two local North London Year 4 classes to join us for the day to learn about how we care for patients with rare diseases.

A man with a white shirt and sleeves rolled up plays with trains at a table with a young boy. Two adults are smiling in the background and it looks like they are his parents

Professor Francesco Muntoni wins prestigious research prize

12 Mar 2026, 9:49 a.m.

Professor Francesco Muntoni, GOSH Paediatric Neurology Consultant, has been awarded the 2026 Novo Nordisk Prize in recognition of his pioneering work transforming the outlook for children with Duchenne muscular dystrophy (DMD).

Four researchers wearing lab coats in a line, with the staff member at the front holding a pipette

GOSH secures £1.4m in NIHR capital equipment funding to boost research capability

11 Mar 2026, 12:23 p.m.

This investment will significantly strengthen our research infrastructure and enhance our ability to deliver world‑leading paediatric research across the whole hospital.

Landmark decision to screen for spinal muscular atrophy at birth

From complex science to clear communication

Gene therapy successfully treats deadly childhood liver disease in mice

World-first gene therapy to target devastating rare immune disorder

Shaping better research from the start

8 years of advancing care through data and innovation

UK-wide excellence in paediatrics

Researchers identify brain network linked to deadliest childhood brain cancer

Professor Jugnoo Rahi awarded prestigious Bowman Medal by the Royal College of Ophthalmologists

Professor Helen Cross elected to the Academy of Medical Sciences

Spotlight on our Research Co-ordinators

Better understanding leukaemia for children with down syndrome

Gentler treatment eliminates early deaths for children with relapsed leukaemia

NHS eye gene therapy restores Saffie's sight

£3M study led by patient voices targets pain in inflammatory arthritis

GOSH joins European health leaders to shape the future of paediatric data sharing

Engineered tissue offers hope for children born with ‘missing’ food pipe

GOSH celebrates Rare Disease Day 2026 with local community

Professor Francesco Muntoni wins prestigious research prize

GOSH secures £1.4m in NIHR capital equipment funding to boost research capability

World-first gene therapy to target devastating rare immune disorder