Research and Innovation

Carrying out research into the best way to fight children’s illnesses has been one of our three main ambitions ever since our hospital opened in 1852.

We’ve come a long way since then and, with our research partner the UCL Great Ormond Street Institute of Child Health (ICH), we now form the largest paediatric centre in Europe dedicated to both clinical and basic scientific research.

Read our latest stories - and find out about our research opportunities.

We are committed to carrying out pioneering research to find treatments and cures for some of the most complex illnesses, for the benefit of children here in the UK and worldwide.

Great Ormond Street Hospital (GOSH) and UCL Great Ormond Street Institute of Child Health (ICH) were awarded NIHR Biomedical Research Centre (BRC) status in 2007, and had the award renewed in 2011. This was in recognition of the research conducted in the organisation. We are the only paediatric BRC in the UK.

Discover more about research and innovation at GOSH and the ICH.

Read our latest patient stories and find out about our research opportunities.

Find out more about the research infrastructure and facilities we have available.

Information for commercial and academic partners about how to work with us.

Learn more about the support and resources available to researchers. 

Research news

Learn about the latest research and innovation at Great Ormond Street Hospital.

Gene therapy treatment manufactured at GOSH and ICH used to treat world's first patient with life limiting genetic condition, MPSIIIA

A two-year old patient at the Royal Manchester Children’s Hospital (RMCH) is the first in the world to receive a pioneering new gene therapy treatment for the rare and life-limiting genetic condition, Mucopolysaccharidosis IIIA (MPSIIIA). The treatment was manufactured at Great Ormond Street Hospital (GOSH) and the UCL Great Ormond Street Institute of Child Health (ICH) after being developed by RMCH and the University of Manchester.

Research successes highlighted at BRC showcase event

Over 150 people came along to the National Institute for Health Research (NIHR) GOSH Biomedical Research Centre showcase last month to hear about our latest research highlights - from cutting edge CAR-T therapies for leukaemia, to Oculome genomic sequencing to diagnose rare childhood eye conditions.