This committee, chaired by Dr Owen Arthurs, sits monthly (except August) to review protocols. It is composed of a combination of senior clinicians actively engaged in clinical research, psychologists, allied health professionals, academics and a statistician. CRAC can suggest the use of extra GOSH resources and will provide advice on statistics, research methods and research ethics.
We strongly recommend that you submit your application to CRAC prior to seeking ethics or regulatory approval.
CRAC Guidance_0 (326.68 KB)
Research is defined by the Research Governance Framework as an “attempt to derive generalisable new knowledge by addressing clearly defined questions with systematic and rigorous methods.”
Other activities such as clinical audit, local developments of existing research, the introduction of clinical innovations, service evaluations, patient and staff surveys and quality assurance programmes may not qualify as research even though they may use similar methods. For further information about what constitutes research and whether it needs REC approval, please refer to the NRES decision tools at
CRAC does not need to consider service evaluations or clinical audits. These should instead be registered with the clinical audit team; please contact email@example.com, the GOSH clinical audit manager.
If you are unsure whether your project requires CRAC approval, please email CRAC.Admin@gosh.nhs.uk for advice.
|Is your project clinical?||It involves any GOSH resources, GOSH staff or GOSH patients (including patient samples or data).|
|Is your project own-account?||It is unfunded and you have not secured funding to cover the cost of GOSH/ICH resources (staff time, service support costs, consumables) associated with the project.|
To submit an application
To submit an own-account clinical research project for review by CRAC you need to complete the following documents:
- A study protocol
- Other relevant documents such as: Questionnaires, Patient Information sheets, consent forms.
Please nominate two peer reviewers on your application form for all new studies. Failure to nominate peer reviewers will result in your application being returned.
If your study is a multi-centre study and/or has already been peer reviewed then you do not have to nominate two peer reviewers; instead, you need only provide evidence of the peer review.
When completed, the application form must be sent by email to CRAC.Admin@gosh.nhs.uk (see right for submission dates).
There is the opportunity to attend the CRAC meeting to discuss your application in person, the committee secretary will organise this once your CRAC application has been registered.
Once your application has been reviewed, the committee secretary will contact you to inform you of the outcome.