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Biomedical Research Centre news

Gene therapy offers potential to extend lives of children with rare immune disorder

30 Apr 2025, 10 p.m.

Children have had their lives changed by a ground-breaking gene therapy treatment at Great Ormond Street Hospital for a rare immunodeficiency.

A young girl with short brown hair is smiling in front of a blue sky while sitting in black chair

Cutting-edge genomic technology saves girl from rare brain infection

30 Apr 2025, 8:14 a.m.

Great Ormond Street Hospital has launched the UK’s first accredited ‘metagenomics’ testing service, that allows clinicians to identify infections that are otherwise undetectable.

New research analyses key immune cell

28 Mar 2025, 11:16 a.m.

A new study led by researchers at University College London Great Ormond Street Institute of Child Health has found that women have a higher proportion of key immune cells between puberty and menopause.

First patient treated with groundbreaking gene therapy trial

21 Mar 2025, 9:51 a.m.

A baby boy born with a rare condition has become the first in the world to be treated with a new, potentially lifechanging, investigational gene therapy on a clinical trial at Great Ormond Street Hospital (GOSH).

two women in lab coats stood in front of a table and young child pouring bottle

Reflecting on rare disease day 2025

7 Mar 2025, 12:23 p.m.

Rare Disease Day is an international event which takes place annually on the last day of February. The date is chosen because in leap years it is February 29, the rarest date!