DRIVE resources and publications

This report explains how in 5 years, the first-of-its-kind DRIVE unit led to improvements in research and innovation, and care for children and young people with serious and complex health conditions.

Read and download the report here

We have created a playbook of learnings where we outline our experiences of the start of our partnership journey; what has gone well and what hasn’t, and how we have worked in partnership to harness the best from two very different cultures across the NHS and industry.

In the playbook we provide candid and constructive reflections on real-world issues, barriers and potential mitigations, moving from strategy to sustainable impact, all of which can be scalable across the NHS and beyond. 

We hope this will be a useful guide for other healthcare organisations interested in working towards the future of health using healthcare data.

​​Read and download the playbook here.

Following the introduction of our Electronic Patient Record in 2017, we began to build GOSH DRIVE, a hub for innovation with a team of digital engineers, governance experts, data scientists and clinical experts.

With a vision to harness the secondary use of routinely collected data from EPR and other systems, we partnered with Ardihia to build a state-of-the-art DRE infrastructure.

Our aim being to improve the operational management and planning of the hospital and to support clinical and informatics research activity.

Our new paper showcases how much we have achieved in the first 8 years of our partnership.

We are really proud of the hard work that the team have and continue to put into ensuring patient data is used ethically and responsibly as we strive to improve outcomes for children and young people with rare and complex diseases.

Read and download the paper here.

This report outlines methodology and findings of an extensive London-wide evaluation of AI-Scribing (Ambient Voice Technology).

The study, led by GOSH DRIVE was conducted across nine NHS sites in London to assess the impact of an AI-scribing tool, TORTUS, which automatically transcribes consultations and drafts summarised clinical notes for clinicians to review.

Over 17,000 patient encounters were evaluated across a diverse range of sites including hospitals, GP practices, mental health services and ambulance teams.

Read our news article here.

View and download the report:

The use of Ambient Voice Technology with Generative Artificial Intelligence in Multiple Clinical Settings Across the NHS

In order to support secondary use and analysis of this data, the GOSH/Roche partnership has developed a Natural Language Processing (NLP) pipeline that can extract relevant structured information from PDF and convert it into a standardised format that enables further analysis. This work will support improved prediction, prevention, diagnosis and precision medicine at scale using information that has not previously been available.View on GitHub here

PICTURE helps authorised healthcare professionals and researchers explore and analyse patient cohort data.

It’s a user-friendly tool built entirely in R (a programming language used for data analysis), and it runs as a standalone app using RShiny, which means it’s easy to use and doesn’t need any extra software.

It’s already been used in several projects to support clinical research, generate new ideas, and carry out audits.

Key features include:

Flexible patient group analysis: Easily define and compare different patient groups.
Clear summaries and visuals: Built-in charts and tables based on real-world needs. Customisable design: You can tailor it to your own needs or add new tools.
Ready to use elsewhere: It’s designed to work in other hospitals and healthcare settings to speed up research and innovation.

To make it even easier to try out, we’ve added support for a widely used healthcare data format (OMOP CDM) and included ‘dummy’ data, so it works straight away. No real patient data is shared.

PICTURE has been built and developed internally at GOSH DRIVE thanks to funding support from GOSH Charity for our Clinical Informatics Research Programme. We also received advice and support through our long-standing partnership with Roche UK which aims to accelerate data science and personalised medicine.

We hope that by openly sourcing the code, we can help to boost clinical informatics across the entire system and ultimately speed up discovery of new treatments and improve outcomes for children and young people.

We would love for colleagues across the system to test it out and provide feedback -

gosh-dre/picture.platform, gosh-dre/driveanalytics, gosh-dre/picture_preprocessing, gosh-dre/picture_preprocessing

Contribute to gosh-dre/picture.platform development by creating an account on GitHub.

Implementation of an NLP workflow that pre-processes patient/parent feedback of GOSH patient that comes in through data collection directly from parents with a mobile app or data entry by routine data entry the patient experience team engages in. https://github.com/gosh-dre/Themiator

Minimal Data Maximum Impact: Lessons Learned from Real-World Unstructured Data in Paediatric Care. Jaskaran Singh Kawatra, Sebin Sabu, Pavithra Rajendran, Caroline Baumgartner, Avish Vijayaraghavan, Ewart Jonny Sheldon, John Booth, Neil Sebire, Shiren Patel, Alexandros Zenonos, Rebecca Pope Proceedings of The First AAAI Bridge Program on AI for Medicine and Healthcare, PMLR 281:70-78, 2025.

Investigating General-Purpose Large Language Models for Patient Information Extraction: A Case Study on Real-World Cardiac MRI Reports. Sebin Sabu, Pavithra Rajendran, Ewart Jonny Sheldon, Alexandros Zenonos, Shiren Patel, Andrew Taylor, Rebecca Pope, Neil Sebire Proceedings of The First AAAI Bridge Program on AI for Medicine and Healthcare, PMLR 281:63-69, 2025.

Clinical Informatics Research Programme

1. Alderman JE, Palmer J, Laws E, (Sebire N) et al. Tackling algorithmic bias and promoting transparency in health datasets: the STANDING Together consensus recommendations. Lancet Digit Health. 2025 Jan;7(1):e64-e88.
2. Alarilla A, Sebire NJ, Keith J et al. A scoping review of the electronic collection and capture of patient reported outcome measures for children and young people in the hospital setting. PLOS Digit Health. 2025 Jan 6;4(1):e0000704.
3. Li J, Zakka KR, Booth J, Rigny L, Ray S, Cortina-Borja M, Barnaghi P, Sebire N. Discovering patient groups in sequential electronic healthcare data using unsupervised representation learning. BMC Med Inform Decis Mak. 2025 Jan 28;25(1):45
4. Walsh C, Capstick A, Fletcher-Lloyd N, True J; CR&T Group; Nilforooshan R, Barnaghi P. Longitudinal study of care needs and behavioural changes in people living with dementia using in-home assessment data. Commun Med (Lond). 2025 Jan 10;5(1):14.
5. Bafaloukou M, Schalkamp AK, Fletcher-Lloyd N, Capstick A, Walsh C, Sandor C, Kouchaki S; CR&T Group; Nilforooshan R, Barnaghi P. An interpretable machine learning tool for in-home monitoring of agitation episodes in people living with dementia: a proof-of-concept study. EClinicalMedicine. 2025 Jan 20;80:103032.
6. Sebire NJ, Adams A, Celi L, Charlesworth A, Gorgens M, Gorsky M, Landeg O, Nagasawa Y, Nimako KT, Onoka C, Roder-DeWan S, Watts N, McKee M. The Future Hospital in Global Health Systems: The Future Hospital Within the Healthcare System. Int J Health Plann Manage. 2025 Feb;160:67-72
7. Yuan Y, Hu W, Chen C, Yao R, Zhang S, Zhu X, Xu B, Huang Z, Zhang S, Wang X, Zheng M, Huang X, Standing JF. Pharmacokinetic, Pharmacodynamic and Pharmacogenetic Studies Related to Vincristine-Induced Peripheral Neuropathy in Chinese Pediatric ALL Patients. Clin Pharmacol Ther. 2025 Feb;117(2):454-464.
8. Huo Z, Booth J, Monks T, Knight P, Watson L, Peters M, Pagel C, Ramnarayan P, Li K. Dynamic mortality prediction in critically Ill children during interhospital transports to PICUs using explainable AI. NPJ Digit Med. 2025 Feb 17;8(1):108.
9. Uthayananthan P, Tanwar N, Rahi JS, Dick AD, Solebo AL. Imaging-Based Detection of Anterior Chamber Inflammation: A Comparative Diagnostic Accuracy Study. Am J Ophthalmol. 2025 Feb;270:131-139.
10. Schmidt DC, Martinussen T, Solebo AL, Larsen DA, Bach-Holm D, Kessel L. Comparing glaucoma risk in children receiving low-dose and high-dose glucocorticoid treatment after cataract surgery. Acta Ophthalmol. 2025 Feb;103(1):43-49.
11. Shelmerdine SC. Rethinking our relationship with AI: for better or worse, richer or poorer? Eur Radiol. 2025 Feb;35(2):1101-1104.
12. Kotter E, D'Antonoli TA, Cuocolo R, Hierath M, Huisman M, Klontzas ME, Martí-Bonmatí L, May MS, Neri E, Nikolaou K, Pinto Dos Santos D, Radzina M, Shelmerdine SC, Bellemo A; European Society of Radiology (ESR). Guiding AI in radiology: ESR's recommendations for effective implementation of the European AI Act. Insights Imaging. 2025 Feb 13;16(1):33.
13. Togher D, Dean G, Moon J, Mayola R, Medina A, Repec J, Meheux M, Mather S, Storey M, Rickaby S, Abubacker MZ, Shelmerdine SC. Evolution of radiology staff perspectives during artificial intelligence (AI) implementation for expedited lung cancer triage. Clin Radiol. 2025 Feb;81:106704.
14. Marijnen MC, Bügel MI, Khong TY, Sebire NJ, Heazell AEP, Ganzevoort W, Bloomfield FH, Kooi EMW, van der Meeren LE, Gordijn SJ. Priority Setting Partnership on Placental Pathology: Consensus recommendations for placental research. Placenta. 2025 Feb;160:67-72.
15. Howell KB, White SM, McTague A, D'Gama AM, Costain G, Poduri A, Scheffer IE, Chau V, Smith LD, Stephenson SEM, Wojcik M, Davidson A, Sebire N, Sliz P, Beggs AH, Chitty LS, Cohn RD, Marshall CR, Andrews NC, North KN, Cross JH, Christodoulou J, Scherer SW. International Precision Child Health Partnership (IPCHiP): an initiative to accelerate discovery and improve outcomes in rare pediatric disease. NPJ Genom Med. 2025 Feb 27;10(1):13.
16. Hutchinson JC, Picarsic J, McGenity C, Treanor D, Williams B, Sebire NJ. Whole Slide Imaging, Artificial Intelligence, and Machine Learning in Pediatric and Perinatal Pathology: Current Status and Future Directions. Pediatr Dev Pathol. 2025 Mar-Apr;28(2):91-98.
17. Ashworth E, Allan E, Pauling C, Laidlow-Singh H, Arthurs OJ, Shelmerdine SC. Artificial intelligence (AI) in radiological paediatric fracture assessment: an updated systematic review. Eur Radiol. 2025 Mar 10.
18. Granger E, Todd J, Charman SC, Cromwell E, Davies G, et al. CF Trial Emulation Network (CF-TEN). Effects of azithromycin in young adults with cystic fibrosis: a protocol for emulating a published randomised controlled trial using registry data. BMJ Open. 2025 Mar 25;15(3):e091357.
19. Shaw M, Cross N, Richardson R, Crook R, Thirulchelvam T, Issitt RW. The effect of excessive gas to blood ratios in an ECMO oxygenator. Perfusion. 2025 Apr;40(3):678-685.
20. Matos C, Livermore P, et al. Patients', caregivers and clinicians' perspectives on education and support about methotrexate: survey to 26 European Countries. ARP Rheumatol. 2025 Apr-Jun;4(2):91-105.
21. Keys R, Marshall P, Stuart G, and O'Kane AA. 2025. Rethinking Lived Experience in Chronic Illness: Navigating Bodily Doubt with Consumer Technology in Atrial Fibrillation Self-Care. In Proceedings of the 2025 CHI Conference on Human Factors in Computing Systems (CHI '25). Association for Computing Machinery, New York, NY, USA, Article 355, 1–19. 2025.
22. Jane K, Wood D, Gallagher K, Livermore P, Shoemark H, Robert G. Parents' experiences of psychotherapeutic support on the neonatal unit: A mixed methods systematic review to inform intervention development for a multicultural population. Nurs Crit Care. 2025 May;30(3):e13194
23. Kupiec K, Najafi A, Ledochowski J, Chesters H, Livermore P. A mixed-method systematic review evaluating interventions in paediatric rheumatology to address caregiver support and well-being. Pediatr Rheumatol Online J. 2025 May 16;23(1):54.
24. Bowyer SA, Booth J, Key D, Pissaridou E, Bryant WA, Hemingway H, Sebire NJ. Increasing diagnoses per patient admission at a specialist children's hospital: A retrospective study. PLoS One. 2025 May 6;20(5):e0322997.
25. Sebire NJ, Adams A, Arpiainen L, Celi L, Charlesworth A, Gorgens M, Gorsky M, Magrabi F, Nagasawa Y, Onoka C, McKee M. The Future Hospital in Global Health Systems: The Future Hospital as an Entity. Int J Health Plann Manage. 2025 May;40(3):730-740.
26. Sebire NJ, Adams A, Celi L, Charlesworth A, Gorgens M, Gorsky M, Landeg O, Nagasawa Y, Nimako KT, Onoka C, Roder-DeWan S, Watts N, McKee M. The Future Hospital in Global Health Systems: The Future Hospital Within the Healthcare System. Int J Health Plann Manage. 2025 May;40(3):741-751.
27. Newlands F, Markan T, Pomfret I, Davey E, King T, Roach A, Wagstaff M, Osborn TG, Shafran R, Livermore P, de Haan M, Wolstencroft J, Bennett S. "A PhD is just going to somehow break you": A qualitative study exploring the role of peer support for doctoral students. PLoS One. 2025 Jun 9;20(6):e0325726.
28. Bray L, Leahy A, Aarvold A, Bailey H, Barling J, Beesley R, Chew C, Ciurtin C, Elliott E, Healy K, Hughes K, Livermore P, et al. Hot, swollen or stiff joints in children and young people: British Society for Rheumatology guideline scope. Rheumatol Adv Pract. 2025 Jun 2;9(2):rkaf047.
29. Stein DF, Carter MJ, Booth J, Peters MJ, Ray S, Sebire NJ, Barnaghi P, Cortina-Borja M. Prediction cardiovascular deterioration in a paediatric intensive care unit (PicEWS): a machine learning modelling study of routinely collected health-care data. EClinicalMedicine. 2025 Jun 18;85:103255.
30. Bazyleva E, van der Meeren LE, Schoots MH, Ernst LM, Khong TY, Sebire NJ, Seegers P, Gordijn SJ. The Amsterdam Criteria and beyond: development of a Standardized Structured Reporting (SSR) tool for diagnosis of placental pathology. Virchows Arch. 2025 Jun 18.
31. McGenity C, Cratchley A, Aldridge J, Sayers C, Campbell WS, Dash RC, Flanagan AM, Sebire N, Wright A, Akhtar W, Treanor D. Development of a national pathology training system using digital pathology and SNOMED-CT. J Pathol Inform. 2025 Jun 18;18:100456
32. Visram S, Rogers Y, Molyneux G, Sebire NJ; Delphi Panel. Technology adoption in healthcare: Delphi consensus for the early exploration and agile adoption of emerging healthcare technology conceptual framework. BMJ Health Care Inform. 2025 Jul 11;32(1):e101349.
33. Lau CWY, Kupiec K, Livermore P. Exploring the Acceptance and Opportunities of Using a Specific Generative AI Chatbot to Assist Parents in Managing Pediatric Rheumatological Chronic Health Conditions: Mixed Methods Study. JMIR Pediatr Parent. 2025 Jul 1;8:e70409.
34. Jane K, Hayns-Worthington R, Gallagher K, Livermore P, Shoemark H, Robert G. Supporting continuing bonds for parents with infants with uncertain futures on neonatal units in the United Kingdom: co-designing a culturally sensitive music therapy intervention. Front Psychiatry. 2025 Jul 21;16:1633878.
35. Ravelli A, Rosina S, MacMahon JM, Baird T, Rebollo-Giménez AI, Hinze C, McCann LJ, Reed AM, Rider LG, Arvigo M, Bader-Meunier B, Bruno C, Caifeng L, Campanilho-Marques R, Cuccato S, Fiorillo C, Hahn NA, Huber AM, Jansen M, Kasapcopur O, Katsikas MM, Kim S, Livermore P, et al. Treating juvenile dermatomyositis to target: Paediatric Rheumatology European Society/Childhood Arthritis and Rheumatology Research Alliance-endorsed recommendations from an international task force. Ann Rheum Dis. 2025 Jul;84(7):1055-1067.
36. Masoud S, Wong K, Pitcher D, Downward L, Proudfoot C, Webb NJA; RaDaR Consortium; Wong EKS, Gale DP. Quantifying association of early proteinuria and estimated glomerular filtration rate changes with long-term kidney failure in C3 glomerulopathy and immune-complex membranoproliferative glomerulonephritis using the United Kingdom RaDaR Registry. Kidney Int. 2025 Sep;108(3):455-469.

Developing a conceptual framework for the early adoption of healthcare technologies in hospitals. Visram, S., Rogers, Y. & Sebire, N.J. Nat Med (2024). https://doi.org/10.1038/s41591-024-02860-8

Safety of virtual reality use in children: a systematic review. Bexson, C., Oldham, G. & Wray, J. Eur J Pediatr (2024). https://doi.org/10.1007/s00431-024-05488-5

GIF: An Automated Genomic Information Finder to Extract Data from Reports. Pavithra Rajendran, Alexandros Zenonos, Sebin Sabu, Anastasia Spiridou, Helena Spiridou Goncalves, Nastazja Laskowski, Daniel Key, Shiren Patel, Rebecca Pope, Neil Sebire DOI10.3233/FAIA241059

Clinical Informatics Research Programme

1. Getzen E, Tan AL, Brat G, Omenn GS, Strasser Z; Consortium for Clinical Characterization of COVID-19 by EHR (4CE) (Collaborative Group/Consortium); Long Q, Holmes JH, Mowery D. Leveraging informative missing data to learn about acute respiratory distress syndrome and mortality in long-term hospitalized COVID-19 patients throughout the years of the pandemic. AMIA Annu Symp Proc. 2024 Jan 11;2023:942-950.
2. Southern KW, Addy C, Bell SC, Bevan A, Borawska U, Brown C, Burgel PR, Button B, Castellani C, Chansard A, Chilvers MA, Davies G, et al. Standards for the care of people with cystic fibrosis; establishing and maintaining health. J Cyst Fibros. 2024 Jan;23(1):12-28.
3. Solebo AL, Bellchambers A, Kellett S, Rahi JS, Dick AD. Establishing the Normative Data Set Necessary for Imaging-Based Childhood Uveitis Surveillance: A Cross-Sectional Study. Invest Ophthalmol Vis Sci. 2024 Jan 2;65(1):9.
4. Toader AM, Campbell MK, Quint JK, Robling M, Sydes MR, Thorn J, Wright-Hughes A, Yu LM, Abbott TEF, Bond S, Caskey FJ, Clout M, Collinson M, Copsey B, Davies G, et al. Using healthcare systems data for outcomes in clinical trials: issues to consider at the design stage. Trials. 2024 Jan 29;25(1):94.
5. Capstick A, Palermo F, Zakka K, Fletcher-Lloyd N, Walsh C, Cui T, Kouchaki S, Jackson R, Tran M, Crone M, Jensen K, Freemont P, Vaidyanathan R, Kolanko M, True J, Daniels S, Wingfield D; CR&T Group; Nilforooshan R, Barnaghi P. Digital remote monitoring for screening and early detection of urinary tract infections. NPJ Digit Med. 2024 Jan 13;7(1):11.
6. Filipow N, Mallon S, Shewaramani S, Kassen R, Wong A. The impact of genetic background during laboratory evolution of Pseudomonas aeruginosa in a cystic fibrosis-like environment. Evolution. 2024 Feb 29;78(3):566-578.
7. Ndosi M, Livermore P. Beyond aches and pain: the hidden economic burden of musculoskeletal conditions in children and adolescents. Evid Based Nurs. 2024 Feb 15:ebnurs-2023-103891.
8. Lanis A, Alexanderson H, Ardalan K, Edison S, Graham CD, de Groot I, Gupta L, Kim S, Knight AM, Kobert L, Livermore P et al. Mental health in paediatric and adult myositis-related diseases: current state of research, interventions, and future steps from the MIHRA Psychological Impact Scientific Working Group. Clin Exp Rheumatol. 2024 Feb;42(2):413-424.
9. Hayes WN, Laing E, Brown R, Silsby L, Smith L, Thomas H, Kaloyirou F, Sharma R, Griffiths J, Hume-Smith H, Marks SD, Kessaris N, Christian M, Dudley J, Shenoy M, Malina M, Muorah M, Ware N, Yadav P, Reynolds B, Bryant W, Spiridou A, Wray J, Peters MJ. A pragmatic, open-label, randomized controlled trial of Plasma-Lyte-148 versus standard intravenous fluids in children receiving kidney transplants (PLUTO). Kidney Int. 2024 Feb;105(2):364-375.
10. Rostron H, Wright JM, Gilbert AW, Dillon B, Pini S, Redmond AC, Livermore P. Adoption of technology enabled care to support the management of children and teenagers in rheumatology services: a protocol for a mixed-methods systematic review. BMJ Open. 2024 Feb 21;14(2):e082515.
11. Khalil R, Kellett S, Petrushkin H, Twomey C, Rahi J, Solebo AL. Show don't tell: assessing the impact of co-developed patient information videos in paediatric uveitis. Eye (Lond). 2024 Feb;38(2):246-252.
12. Patel RP, Petrushkin H, Etherton K, Terence K, Dick AD, Rahi JS, Solebo AL. Quality assessment of anterior segment OCT images: Development and validation of quality criteria. Photodiagnosis Photodyn Ther. 2024 Feb;45:103886.
13. Filipow N, Bladen M, Raywood E, Robinson E, Chugh D, Douglas H, Thorpe N, O'Connor R, Murray N, Main E. Using reference equations to standardise incremental shuttle walk test performance in children and young people with chronic conditions and facilitate the evaluation of exercise capacity and disease severity. BMJ Open. 2024 Mar 8;14(3):e075733.
14. Macdonald T, Dinnes J, Maniatopoulos G, Taylor-Phillips S, Shinkins B, Hogg J, Dunbar JK, Solebo AL, Sutton H, Attwood J, Pogose M, Given-Wilson R, Greaves F, Macrae C, Pearson R, Bamford D, Tufail A, Liu X, Denniston AK. Target Product Profile for a Machine Learning-Automated Retinal Imaging Analysis Software for Use in English Diabetic Eye Screening: Protocol for a Mixed Methods Study. JMIR Res Protoc. 2024 Mar 27;13:e50568.
15. Wong K, Pitcher D, Braddon F, RaDaR consortium. et al. Effects of rare kidney diseases on kidney failure: a longitudinal analysis of the UK National Registry of Rare Kidney Diseases (RaDaR) cohort. Lancet. 2024 Mar 30;403(10433):1279-1289.
16. Twomey C, McGonigle E, Solebo AL. Co-Creation of a Novel Childhood Onset Rare Disease Self-Care Support Tool. Acad Pediatr. 2024 Mar;24(2):369-372.
17. Teoh LJ, Kellett S, Patel DE, Cortina-Borja M, Solebo AL, Rahi JS. Evaluating the Quantity and Quality of Health Economic Literature in Blinding Childhood Disorders: A Systematic Literature Review. Pharmacoeconomics. 2024 Mar;42(3):275-299.
18. Wagner SK, Raja L, Cortina-Borja M, Huemer J, Struyven R, Keane PA, Balaskas K, Sim DA, Thomas PBM, Rahi JS, Solebo AL, Kang S. Determinants of non-attendance at face-to-face and telemedicine ophthalmic consultations. Br J Ophthalmol. 2024 Mar 20;108(4):625-632.
19. Huang Y, Zhao Y, Capstick A, Palermo F, Haddadi H, Barnaghi P. Analyzing entropy features in time-series data for pattern recognition in neurological conditions. Artif Intell Med. 2024 Apr;150:102821.
20. Hutch MR, et al. Consortium for Clinical Characterization of COVID-19 by EHR (4CE); Visweswaran S, Cai T, Luo Y, Xia Z. Neurological diagnoses in hospitalized COVID-19 patients associated with adverse outcomes: A multinational cohort study. PLOS Digit Health. 2024 Apr 15;3(4):e0000484.
21. Brown J, Cox L, Mulligan K, Wilson S, Heys M, Livermore P, Gray S, Bogosian A. Gaining consensus on emotional wellbeing themes and preferences for digital intervention type and content to support the mental health of young people with long-term health conditions: A Delphi study. Health Expect. 2024 Apr;27(2):e14025.
22. Keys R, Marshall P, Stuart G, and O'Kane AA. 2024. “I think it saved me. I think it saved my heart”: The Complex Journey From Self-Tracking With Wearables To Diagnosis. In Proceedings of the 2024 CHI Conference on Human Factors in Computing Systems (CHI '24). Association for Computing Machinery, New York, NY, USA, Article 138, 1–15.
23. Issitt RW, Cudworth E, Cortina-Borja M, Gupta A, Kallon D, Crook R, Shaw M, Robertson A, Tsang VT, Henwood S, Muthurangu V, Sebire NJ, Burch M, Fenton M. Rapid desensitization through immunoadsorption during cardiopulmonary bypass. A novel method to facilitate human leukocyte antigen incompatible heart transplantation. Perfusion. 2024 Apr;39(3):543-554.
24. Shelmerdine SC. Revolutionising paediatric radiology: the future impact of artificial intelligence. Eur Radiol. 2024 Apr;34(4):2294-2296.
25. Foeldvari I, Bohn M, Petrushkin H, Angeles Han S, Bangsgaard R, Calzada-Hernández J, Constantin T, de Boer JH, Díaz-Cascajosa J, Edelsten C, Glerup M, Ingels H, Kramer S, Miserocchi E, Nordal E, Saurenmann RK, Simonini G, Solebo AL, Titz J, Anton J. A practical approach to uveitis screening in children with juvenile idiopathic arthritis. Br J Ophthalmol. 2024 Apr 4:bjo-2023-324406.
26. Matthews J, Dobra R, Wilson G, Allen L, Bossley C, Brendell R, Brugha R, Brown D, Brown S, Cadiente S, Cameron L, Davies G et al. Levelling the playing field through the London Network of the UK clinical trials accelerator platform. Contemp Clin Trials Commun. 2024 Apr 26;39:101301.
27. Asgari E, Kaur J, Nuredini G, Balloch J, Taylor AM, Sebire N, Robinson R, Peters C, Sridharan S, Pimenta D. Impact of Electronic Health Record Use on Cognitive Load and Burnout Among Clinicians: Narrative Review. JMIR Med Inform. 2024 Apr 12;12:e55499.
28. Livermore P, Kupiec K, Wedderburn LR, Knight A, Solebo AL, Shafran R, Robert G, Sebire NJ, Gibson F; IMPACT Steering Group. Designing, Developing, and Testing a Chatbot for Parents and Caregivers of Children and Young People With Rheumatological Conditions (the IMPACT Study): Protocol for a Co-Designed Proof-of-Concept Study. JMIR Res Protoc. 2024 Apr 3;13:e57238.
29. Ciet P, Eade C, Ho ML, Laborie LB, Mahomed N, Naidoo J, Pace E, Segal B, Toso S, Tschauner S, Vamyanmane DK, Wagner MW, Shelmerdine SC. The unintended consequences of artificial intelligence in paediatric radiology. Pediatr Radiol. 2024 Apr;54(4):585-593.
30. Ibarra Vilar P, Jani JC, Cannie MM, Shelmerdine SC, et al. Postmortem imaging of fetuses at early gestations: A comparison of microfocus computed tomography with postmortem magnetic resonance at 9.4 T and postmortem ultrasound. Prenat Diagn. 2024 May;44(5):572-579.
31. Wong K, Pitcher D, Braddon F et al. RaDaR consortium [Sebire N]. Description and Cross-Sectional Analyses of 25,880 Adults and Children in the UK National Registry of Rare Kidney Diseases Cohort. Kidney Int Rep. 2024 May 9;9(7):2067-2083.
32. Shaw M, Cross N, Richardson R, Crook R, Thirulchelvam T, Issitt RW. The effect of excessive gas to blood ratios in an ECMO oxygenator. Perfusion. 2024 May 23:2676591241256089.
33. Gramegna A, Addy C, Allen L, Bakkeheim E, Brown C, Daniels T, Davies G et al. Standards for the care of people with cystic fibrosis (CF); Planning for a longer life. J Cyst Fibros. 2024 May;23(3):375-387.
34. Kamran R, Jackman L, Chan C, Lee AC, Kamran A, Alli J, Jacklin C, Deck E, Suk Y, Jackman V, Garvilles M, Shelmerdine SC, Doria AS. Pre- and post-COVID-19 gender trends in authorship for paediatric radiology articles worldwide: a systematic review. Pediatr Radiol. 2024 May;54(5):831-841.
35. Ross J, Hammouche S, Chen Y, Rockall AG; Royal College of Radiologists AI Working Group [Shelmerdine S]. Beyond regulatory compliance: evaluating radiology artificial intelligence applications in deployment. Clin Radiol. 2024 May;79(5):338-34.
36. Visram S, Rogers Y, Sebire NJ. Developing a conceptual framework for the early adoption of healthcare technologies in hospitals. Nat Med. 2024 May;30(5):1222-1224.
37. Bonello B, Issitt R, Hughes M, et al. Long-term outcome after neonatal intervention for congenital critical aortic stenosis. Int J Cardiol. 2024 Jun 15;405:131932.
38. Balloch J, Sridharan S, Oldham G, Wray J, Gough P, Robinson R, Sebire NJ, Khalil S, Asgari E, Tan C, Taylor A, Pimenta D. Use of an ambient artificial intelligence tool to improve quality of clinical documentation. Future Healthc J. 2024 Jun 26;11(3):100157.
39. Johnson SM, Penner J, Issitt R et al. One- and Two-Year Multidisciplinary Follow-Up of MIS-C at a Tertiary Hospital: A Retrospective Cohort Study. Pediatr Infect Dis J. 2024 Jun 19.
40. Urwin E, Martin J, Sebire N et al. A SARS-CoV-2 minimum data standard to support national serology reporting. Ann Clin Biochem. 2024 Jun 17:45632241261274.
41. Spear JW, Pissaridou E, Bowyer S, et al. Communicating exploratory unsupervised machine learning analysis in age clustering for paediatric disease. BMJ Health Care Inform. 2024 Jul 29;31(1):e100963.
42. Riley M, Arigliani M, Davies G, Aurora P. Looking beyond LCI: Multiple breath washout phase III slope derived indices and their application in chronic respiratory disease in children. Pediatr Pulmonol. 2024 Jul 19.
43. Booth J, Eriksson MH, Marks SD, Bryant WA, Denaxas S, Pope R, Sebire NJ. A Method to Apply Temporal Graph Analysis on Electronic Patient Record Data to Explore Healthcare Professional-Patient Interaction Intensity: A Cohort Study. BMJ Health & Care Informatics 2024;31:e101072.
44. Rosendahl K, de Horatio LT, Habre C, Shelmerdine SC, Patsch J, Kvist O, Lein RK, Plut D, Enoksen EJ, Avenarius R, Laborie LB, Augdal TA, Simoni P, van Rijn RR, Offiah AC; European Society of Paediatric Radiology (ESPR) Musculoskeletal and Child Abuse Task Forces. The incidence of fractures in children under two years of age: a systematic review. BMC Musculoskelet Disord. 2024 Jul 9;25(1):528
45. Crook R, Cohen M, Mimic B Fenton M, Issitt R. Dual immunoadsorption for ABO-incompatible heart transplantation in a 35 kg child. Perfusion. 2024 Aug 1:2676591241268428.
46. Testi I, Soomro T, Pavesio C, Solebo AL. Ocular inflammatory events following COVID-19 vaccination: reporting of suspected adverse drug reactions to regulatory authorities in the UK. Br J Ophthalmol. 2024 Aug 22;108(9):1200-1203.
47. Eriksson MH, Prentice F, Piper RJ, Wagstyl K, Adler S, Chari A, Booth J, et al. Long-term neuropsychological trajectories in children with epilepsy: does surgery halt decline? Brain. 2024 Aug 1;147(8):2791-2802.
48. Pickles JC, Aquilina K, Chalker J, Dahl C, Devadass A, Mankad K, Merve A, Ahmed M, Nicoll JAR, Bloom T, Hilton DA, Sebire NJ, Hargrave D, Jacques TS. Decision making for health-related research outcomes that alter diagnosis: A model from paediatric brain tumours. Neuropathol Appl Neurobiol. 2024 Aug;50(4):e12994.
49. Heywood WE, Searle J, Collis R, Doykov I, Ashworth M, Sebire N, Bamber A, Gautel M, Eaton S, Coats CJ, Elliott PM, Mills K. A Proof of Principle 2D Spatial Proteome Mapping Analysis Reveals Distinct Regional Differences in the Cardiac Proteome. Life (Basel). 2024 Aug 1;14(8):970.
50. Pope R, Zenonos A, Bryant W, Spiridou A, Key D, Patel S, Robinson J, Styles A, Rockenbach C, Bicknell G, Rajendran P, Taylor AM, Sebire NJ. Real-world learnings for digital health industry-NHS collaboration: Life sciences vision in action. Future Healthc J. 2024 Aug 8;11(3):100168.
51. Testi I, Brandão-de-Resende C, De-La-Torre A, Concha-Del-Rio LE, Cheja-Kalb R, Mahendradas P, Habot-Wilner Z, Yalçındağ N, Markelj Š, Iriqat S, Portero A, Petrushkin H, Pavesio C, Solebo AL. Ocular Inflammatory Events Following COVID-19 Vaccination in the Paediatric Population: A Multinational Case Series. Ocul Immunol Inflamm. 2024 Sep;32(7):1237-1242.
52. Shelmerdine S et al. Artificial intelligence (AI) implementation within the National Health Service (NHS): the South West London AI Working Group experience. Clin Radiol. 2024 Sep;79(9):665-672.
53. Shelmerdine SC, Davendralingam N, Langan D, Palm L, Mangham C, Arthurs OJ; CORNRD Study Collaborators. Post-mortem skeletal survey (PMSS) versus post-mortem computed tomography (PMCT) for the detection of corner metaphyseal lesions (CML) in children. Eur Radiol. 2024 Sep;34(9):5561-5569.
54. Novak A, Hollowday M, Espinosa Morgado AT, Oke J, Shelmerdine S et al. Evaluating the impact of artificial intelligence-assisted image analysis on the diagnostic accuracy of front-line clinicians in detecting fractures on plain X-rays (FRACT-AI): protocol for a prospective observational study. BMJ Open. 2024 Sep 5;14(9):e086061.
55. Quilter EEV, Downes S, Deighan MT et al. A Digital Intervention for Capturing the Real-Time Health Data Needed for Epilepsy Seizure Forecasting: Protocol for a Formative Co-Design and Usability Study (The ATMOSPHERE Study). JMIR Res Protoc. 2024 Sep 19;13:e60129.
56. Parkinson ME, Smith RM, Tanious K, Curtis F, Doherty R, Colon L, Chena L, Horrocks SC, Harrison M, Fertleman MB, Dani M, Barnaghi P, Sharp DJ; UK Dementia Research Institute Care Research & Technology Research Group; Li LM. Experiences with home monitoring technology in older adults with traumatic brain injury: a qualitative study. BMC Geriatr. 2024 Sep 30;24(1):796.
57. Gonzalez Hernandez F, Nguyen Q, Smith VC et al. Named entity recognition of pharmacokinetic parameters in the scientific literature. Sci Rep. 2024 Oct 8;14(1):23485.
58. Booth J et al. A Method to Apply Temporal Graph Analysis on Electronic Patient Record Data to Explore Healthcare Professional-Patient Interaction Intensity: A Cohort Study. BMJ Health Care Inform. 2024 Oct 10;31(1):e101072.
59. Rigny L, Fletcher-Lloyd N, Capstick A, Nilforooshan R, Barnaghi P. Assessment of sleep patterns in dementia and general population cohorts using passive in-home monitoring technologies. Commun Med (Lond). 2024 Oct 31;4(1):222.
60. Klontzas ME, Shelmerdine SC. Radiology staff perspectives are a key determinant for successful AI adoption in clinical practice. Eur J Radiol. 2024 Nov;180:111692.
61. Solebo AL, Horvat-Gitsels L, Twomey C, Wagner SK, Rahi JS. Socioeconomic and demographic patterning of family uptake of a paediatric electronic patient portal innovation. PLOS Digit Health. 2024 Oct 3;3(10):e0000496.
62. Terence K, Cundy O, Kellett S, Dick AD, Rahi J, Solebo AL; Paediatric Ocular Inflammation UNICORN Study Group. Limited Utility of Keratic Precipitate Morphology as an Indicator of Underlying Diagnosis in Ocular Inflammation. Ocul Immunol Inflamm. 2024 Oct;32(8):1511-1516.
63. Tan ALM, Gonçalves RS, Yuan W, Brat GA, Gentleman R, Kohane IS; Consortium for Clinical Characterization of COVID-19 by EHR (4CE). Implications of mappings between International Classification of Diseases clinical diagnosis codes and Human Phenotype Ontology terms. JAMIA Open. 2024 Nov 18;7(4):ooae118.
64. Urwin E, Martin J, Sebire N, Harris A, Johnson J, Masood E, Milligan G, Mairs L, Chuter A, Ferguson M, Quinlan P, Jefferson E. A SARS-CoV-2 minimum data standard to support national serology reporting. Ann Clin Biochem. 2024 Nov;61(6):418-445.
65. Majithia-Beet G, Naemi R, Issitt R. An investigation into the contributing factors to survival of ARDS patients supported by veno-venous ECMO. Perfusion. 2024 Nov 6:2676591241297048.
66. Russell J, Chan EY, Davies G et al. Developing and testing a toolkit of interventions to improve adherence to non-invasive ventilation in children: the SPIRITUS study protocol. BMJ Open. 2024 Nov 28;14(11):e090570.
67. Altabee R, Mwamba MJ, Turner D, Davies G, Abbott J, Simmonds NJ, Whitty JA, Carr SB, Barton G, Cameron RA. Measurement of treatment burden in cystic fibrosis: A systematic review. J Cyst Fibros. 2024 Nov 30:S1569-1993(24)01812-5.
68. Tanriver G, Stanojevic S, Filipow N et al. Using heart rate data from wrist worn activity trackers to define thresholds for moderate to vigorous physical activity in children and young people with cystic fibrosis. J Cyst Fibros. 2024 Nov 6:S1569-1993(24)01807-1.
69. Filipow N et al. Variability in forced expiratory volume in 1 s in children with symptomatically well-controlled asthma. Thorax. 2024 Nov 14;79(12):1145-1150.
70. Alarilla A et al. Routine use of patient-reported experience and outcome measures for children and young people: a scoping review. Syst Rev. 2024 Nov 28;13(1):293.
71. Marijnen MC, Bügel MI, Khong et al. Priority Setting Partnership on Placental Pathology: Consensus recommendations for placental research. Placenta. 2024 Dec 26;160:67-72.
72. Shelmerdine SC, Pauling C, Allan E, Langan D, Ashworth E, Yung KW, Barber J, Haque S, Rosewarne D, Woznitza N, Ather S, Novak A, Theivendran K, Arthurs OJ. Artificial intelligence (AI) for paediatric fracture detection: a multireader multicase (MRMC) study protocol. BMJ Open. 2024 Dec 7;14(12):e084448.
73. Shelmerdine SC, Hickman SE, Jackson N, Cronheim D, Taylor J, Swift AJ, Thurston M, Davies A, Ather S, Doran S, Nash J, Rockall AG; RCR AI Committee & NIHR Imaging Science Working Group. Facilitating the use of routine data to evaluate artificial intelligence solutions: lessons from the NIHR/RCR data curation workshop. Clin Radiol. 2024 Dec;79(12):892-902.
74. Lee L, Salami RK, Martin H, Shantharam L, Thomas K, Ashworth E, Allan E, Yung KW, Pauling C, Leyden D, Arthurs OJ, Shelmerdine SC. "How I would like AI used for my imaging": children and young persons' perspectives. Eur Radiol. 2024 Dec;34(12):7751-7764.
75. Hoppe JE, Kasi AS, Pittman JE, Jensen R, Thia LP, Robinson P, Tirakitsoontorn P, Ramsey B, Mall MA, Taylor-Cousar JL, McKone EF, Tullis E, Salinas DB, Zhu J, Chen YC, Rodriguez-Romero V, Sosnay PR, Davies G; VX21-121-105 Study Group. Vanzacaftor-tezacaftor-deutivacaftor for children aged 6-11 years with cystic fibrosis (RIDGELINE Trial VX21-121-105): an analysis from a single-arm, phase 3 trial. Lancet Respir Med. 2024 Dec 20:S2213-2600(24)00407-7.
76. Bijlani N, Maldonado OM, Nilforooshan R; CR&T Group; Barnaghi P, Kouchaki S. Utilizing graph neural networks for adverse health detection and personalized decision making in sensor-based remote monitoring for dementia care. Comput Biol Med. 2024 Dec;183:109287.

1. Rapid desensitization through immunoadsorption during cardiopulmonary bypass. A novel method to facilitate human leukocyte antigen incompatible heart transplantation. Issitt RW, Cudworth E, Cortina-Borja M, Gupta A, Kallon D, Crook R, Shaw M, Robertson A, Tsang VT, Henwood S, Muthurangu V, Sebire NJ, Burch M, Fenton M. Perfusion. 2023 Jan 10:2676591221151035.
   
2. Providing a catering liaison service between inpatient families and the hospital kitchen. Wray J, Bexson C, Gough P et al British Journal of Healthcare Management. 2023. https://doi. org/10.12968/bjhc.2023.007
   

Clinical Informatics Research Programme

1. Naidoo J, Shelmerdine SC, Charcape CFU, Sodhi AS. Artificial Intelligence in Paediatric Tuberculosis. Pediatr Radiol. 2023 Jan 28:1–13.
2. Visram S, Leyden D, Annesley O, Bappa D, Sebire NJ. Engaging children and young people on the potential role of artificial intelligence in medicine. Pediatr Res. 2023 Jan;93(2):440-444.
3. Privitera L, Musleh L, Paraboschi I, Ogunlade O, Ogunbiyi O, Hutchinson JC, Sebire N, Beard P, Giuliani S. Dynamic Changes in Microvascular Density Can Predict Viable and Non-Viable Areas in High-Risk Neuroblastoma. Cancers (Basel). 2023 Feb 1;15(3):917.
4. Svedberg M, Imberg H, Gustafsson PM, Tiddens H, Davies G, Lindblad A. Longitudinal lung clearance index and association with structural lung damage in children with cystic fibrosis. Thorax. 2023 Feb;78(2):176-182.
5. Rockall AG, Shelmerdine SC, Chen M. AI and ML in radiology: Making progress. Clin Radiol. 2023 Feb;78(2):81-82
6. David MCB, Kolanko M, Del Giovane M, Lai H, True J, Beal E, Li LM, Nilforooshan R, Barnaghi P, Malhotra PA, Rostill H, Wingfield D, Wilson D, Daniels S, Sharp DJ, Scott G. Remote Monitoring of Physiology in People Living With Dementia: An Observational Cohort Study. JMIR Aging. 2023 Mar 9;6:e43777.
7. Knowles RL, Solebo AL, Sampaio MA, Brown CR, Sargent J, Oluonye N, Rahi J. Incidence, aetiology and neurodisability associated with severe microcephaly: a national surveillance study. Arch Dis Child. 2023 Mar;108(3):211-217.
8. Raywood E, Shannon H, Filipow N, Tanriver G, Stanojevic S, Kapoor K, Douglas H, O'Connor R, Murray N, Black B, Main E. Quantity and quality of airway clearance in children and young people with cystic fibrosis. J Cyst Fibros. 2023 Mar;22(2):344-351.
9. Williams ADN, Davies G, Farrin AJ, Mafham M, Robling M, Sydes MR, Lugg-Widger FV. A DELPHI study priority setting the remaining challenges for the use of routinely collected data in trials: COMORANT-UK. Trials. 2023 Mar 30;24(1):243.
10. Hayward A, Robertson A, Thiruchelvam T, Broadhead M, Tsang VT, Sebire NJ, Issitt RW. Oxygen delivery in pediatric cardiac surgery and its association with acute kidney injury using machine learning. J Thorac Cardiovasc Surg. 2023 Apr;165(4):1505-1516.
11. Laborie LB, Naidoo J, Pace E, Ciet P, Eade C, Wagner MW, Huisman TAGM, Shelmerdine SC. European Society of Paediatric Radiology Artificial Intelligence taskforce: a new taskforce for the digital age. Pediatr Radiol. 2023 Apr;53(4):576-580.
12. Turmezei TD, Shelmerdine SC, Ashok AH, Goh V; Royal College of Radiologists Academic Committee. Academic clinical fellows in radiology: how can we improve success? Clin Radiol. 2023 Apr;78(4):e300-e310.
13. Horvat-Gitsels LA, Cortina-Borja M, Solebo AL, Rahi JS. Impaired vision and physical activity in childhood and adolescence: findings from the Millennium Cohort Study. Br J Ophthalmol. 2023 Apr;107(4):588-594.
14. Rostron H, Livermore P. The benefits of a peer-support group for paediatric rheumatology nurses working in isolation. Rheumatol Adv Pract. 2022 May 19;6(2):rkac043.
15. Vestesson EM et al. Consultation Rate and Mode by Deprivation in English General Practice From 2018 to 2022: Population-Based Study. JMIR Public Health Surveill. 2023 May 2;9:e44944.
16. Zhang HG et al. Consortium for Clinical Characterization of COVID-19 by EHR (4CE). Potential pitfalls in the use of real-world data for studying long COVID. Nat Med. 2023 May;29(5):1040-1043.
17. Parkinson ME, Doherty R, Curtis F, Soreq E, Lai HHL, Serban AI, Dani M, Fertleman M, Barnaghi P, Sharp DJ, Li LM; UK Dementia Research Institute Care Research & Technology Research Group. Using home monitoring technology to study the effects of traumatic brain injury on older multimorbid adults: protocol for a feasibility study. BMJ Open. 2023 May 22;13(5):e068756
18. Wagner SK, Raja L, Cortina-Borja M, Huemer J, Struyven R, Keane PA, Balaskas K, Sim DA, Thomas PBM, Rahi JS, Solebo AL, Kang S. Determinants of non-attendance at face-to-face and telemedicine ophthalmic consultations. Br J Ophthalmol. 2023 May 22:bjo-2022-322389.
19. Teoh LJ, Solebo AL, Rahi JS; British Childhood Visual Impairment and Blindness Study Interest Group. Temporal trends in the epidemiology of childhood severe visual impairment and blindness in the UK. Br J Ophthalmol. 2023 May;107(5):717-724.
20. Filipow N, Main E, Tanriver G, Raywood E, Davies G, Douglas H, Laverty A, Stanojevic S. Exploring flexible polynomial regression as a method to align routine clinical outcomes with daily data capture through remote technologies. BMC Med Res Methodol. 2023 May 11;23(1):114.
    
21. Macdougall A, Jarvis D, Keogh RH, Bowerman C, Bilton D, Davies G et al. Trajectories of early growth and subsequent lung function in cystic fibrosis: An observational study using UK and Canadian registry data. J Cyst Fibros. 2023 May;22(3):388-394.
22. Petrushkin H, Solebo AL. Imaging inflammation in early-onset sarcoidosis: granulomatous anterior uveitis in a 7-year-old girl. Lancet. 2023 Jun 10;401(10392):1963.
23. Papachristou N, Kotronoulas G, Dikaios N, Allison SJ, Eleftherochorinou H, Rai T, Kunz H, Barnaghi P, Miaskowski C, Bamidis PD. Digital Transformation of Cancer Care in the Era of Big Data, Artificial Intelligence and Data-Driven Interventions: Navigating the Field. Semin Oncol Nurs. 2023 Jun;39(3):151433.
24. Rangelov B, Young A, Lilaonitkul W, Aslani S, Taylor P, Guðmundsson E, Yang Q, Hu Y, Hurst JR, Hawkes DJ, Jacob J; Тhe NCCID Collaborative. Delineating COVID-19 subgroups using routine clinical data identifies distinct in-hospital outcomes. Sci Rep. 2023 Jun 20;13(1):9986.
25. Khalil R, Kellett S, Petrushkin H, Twomey C, Rahi J, Solebo AL. Show don't tell: assessing the impact of co-developed patient information videos in paediatric uveitis. Eye (Lond). 2023 Jul 17.
26. Meshaka R, Gaunt T, Shelmerdine SC. Artificial intelligence applied to fetal MRI: A scoping review of current research. Br J Radiol. 2023 Jul;96(1147):20211205.
27. Solebo AL. Why Do We Treat? Defining Disease Control in Juvenile Idiopathic Arthritis-Associated Uveitis. J Rheumatol. 2023 Jul 1:jrheum.2022-1336.
28. Etherton K, Rahi JS, Petrushkin H, Dick AD, Akbarali S, Pattani R, Hau S, Lacassagne S, Liu X, Denniston AK, Solebo AL. Quantitative and qualitative assessment of anterior segment optical coherence tomography capture of disease state in childhood anterior uveitis. Br J Ophthalmol. 2023 Jul;107(7):966-972.
29. Solebo AL, Rahi JS; British Congenital Cataract Interest Group. Delayed diagnosis of congenital cataract in preterm infants: Findings from the IoLunder2 cohort study. PLoS One. 2023 Aug 18;18(8):e0287658.
30. Kellett S, Rahi JS, Dick AD, Knowles R, Tadić V, Solebo AL. UNICORNS: Uveitis in childhood prospective national cohort study protocol. F1000Res. 2023 Aug 30;9:1196.
31. Eriksson MH, Ripart M, Piper RJ, Moeller F, Das KB, Eltze C, Cooray G, Booth J, Whitaker KJ, Chari A, Martin Sanfilippo P, Perez Caballero A, Menzies L, McTague A, Tisdall MM, Cross JH, Baldeweg T, Adler S, Wagstyl K. Predicting seizure outcome after epilepsy surgery: Do we need more complex models, larger samples, or better data? Epilepsia. 2023 Aug;64(8):2014-2026.
32. Eriksson MH, Whitaker KJ, Booth J et al. Pediatric epilepsy surgery from 2000 to 2018: Changes in referral and surgical volumes, patient characteristics, genetic testing, and postsurgical outcomes. Epilepsia. 2023 Sep;64(9):2260-2273.
33. Parkinson ME, Doherty R, Curtis F , Soreq E, Lai HHL, Serban AI, Dani M, Fertleman M, Barnaghi P et al. Using home monitoring technology to study the effects of traumatic brain injury in older multimorbid adults. Ann Clin Transl Neurol. 2023 Sep;10(9):1688-1694.
34. Stirnemann JJ, Besson R, SpaggiarI E, Rojo S, Loge F, Peyro-Saint-Paul H, Allassonniere S, Le Pennec E, Hutchinson C, Sebire N, Ville Y. Development and clinical validation of real-time artificial intelligence diagnostic companion for fetal ultrasound examination. Ultrasound Obstet Gynecol. 2023 Sep;62(3):353-360. *This article was one of the top 10% of most-viewed papers published by the journal in 2023*
35. Palermo F, Chen Y, Capstick A, Fletcher-Loyd N, Walsh C, Kouchaki S, True J, Balazikova O, Soreq E, Scott G, Rostill H, Nilforooshan R, Barnaghi P. TIHM: An open dataset for remote healthcare monitoring in dementia. Sci Data. 2023 Sep 9;10(1):606.
36. D'Gama AM, Mulhern S, Sheidley BR (Gene-STEPS) et al. Evaluation of the feasibility, diagnostic yield, and clinical utility of rapid genome sequencing in infantile epilepsy (Gene-STEPS): an international, multicentre, pilot cohort study. Lancet Neurol. 2023 Sep;22(9):812-825.
37. Wilde H, Tomlinson C, Mateen B A [Hemingway H CVD-COVID-UK/COVID-IMPACT consortium.] et al. Hospital admissions linked to SARS-CoV-2 infection in children and adolescents: cohort study of 3.2 million first ascertained infections in England. BMJ 2023; 382 :e073639.
38. Filipow N, Stanojevic S, Raywood E, Shannon H, Tanriver G, Kapoor K, Douglas H, Davies G, O'Connor R, Murray N, Main E. Real-world effectiveness of airway clearance techniques in children with cystic fibrosis. Eur Respir J. 2023 Sep 9;62(3):2300522.
39. Sperotto F, Gutiérrez-Sacristán A, Makwana S, Consortium for Clinical Characterization of COVID-19 by EHR (4CE) et al. Clinical phenotypes and outcomes in children with multisystem inflammatory syndrome across SARS-CoV-2 variant eras: a multinational study from the 4CE consortium. EClinicalMedicine. 2023 Sep 14;64:102212.
40. Solebo AL, Hysi P, Horvat-Gitsels LA, Rahi JS. Data saves lives: optimising routinely collected clinical data for rare disease research. Orphanet J Rare Dis. 2023 Sep 11;18(1):285.
41. Kelly E, Choi EM, Petrushkin H, Kellett S, Solebo AL. Recognising and managing childhood onset uveitis: a guide for primary care. Br J Gen Pract. 2023 Sep 28;73(735):475-477.
42. Dagliati A, Strasser ZH, Hossein Abad ZS, Consortium for Clinical Characterization of COVID-19 by EHR (4CE) et al. Characterization of long COVID temporal sub-phenotypes by distributed representation learning from electronic health record data: a cohort study. EClinicalMedicine. 2023 Sep 14;64:102210.
43. Vestesson E, De Corte K, Chappell P, Crellin E, Clarke GM. Antibiotic prescribing in remote versus face-to-face consultations for acute respiratory infections in primary care in England: an observational study using target maximum likelihood estimation. eClin. Med 2023 Oct; 64: 102245.
44. Almossawi O et al. Is there a sex difference in mortality rates in paediatric intensive care units?: a systematic review. Front Pediatr. 2023 Oct 9;11:1225684.
45. Rangelov B, Young A, Lilaonitkul W, Тhe NCCID Collaborative [Sebire NJ] et al. Author Correction: Delineating COVID-19 subgroups using routine clinical data identifies distinct in-hospital outcomes. Sci Rep. 2023 Oct 26;13(1):18376.
46. Issitt R et al. Lung transplantation in an 18-month-old with donor specific antibodies - The use of intraoperative, targeted plasma exchange. Perfusion. 2023 Oct;38(7):1530-1533.
47. Livermore P et al. 'The current mental health status of children and young people with JIA, and their wider family': a charity partner collaboration survey. Pediatr Rheumatol Online J. 2023 Oct 6;21(1):111.
48. Granger E, Davies G, Keogh RH. Emulated trial investigating effects of multiple treatments: estimating combined effects of mucoactive nebulisers in cystic fibrosis using registry data. Thorax. 2023 Oct;78(10):1011-1018.
49. Davies G, Keogh RH; Cystic Fibrosis Trial Emulation Network. Trial emulation with observational data in cystic fibrosis. Lancet Respir Med. 2023 Oct;11(10):859-861.
50. Parry W, Fraser C, Crellin E, Hughes J, Vestesson E, Clarke GM. Continuity of care and consultation mode in general practice: a cross-sectional and longitudinal study using patient-level and practice-level data from before and during the COVID-19 pandemic in England. BMJ Open. 2023 Nov 15;13(11):e075152.
51. Solebo AL, Teoh L, Sargent J, Rahi JS; British Childhood Visual Impairment and Blindness Study Interest Group. Avoidable childhood blindness in a high-income country: findings from the British Childhood Visual Impairment and Blindness Study 2. Br J Ophthalmol. 2023 Nov 22;107(12):1787-1792.
52. Cundy O, Lange CA, Bunce C, Bainbridge JW, Solebo AL. Face-down positioning or posturing after macular hole surgery. Cochrane Database Syst Rev. 2023 Nov 21;11(11):CD008228.
53. Lingam I, Okell J, Maksym K, et al. as consortium. Neonatal outcomes following early fetal growth restriction: a subgroup analysis of the EVERREST study. Arch Dis Child Fetal Neonatal Ed. 2023 Nov;108(6):599-606.
54. Arora A, Alderman JE, Palmer J, Ganapathi S, Laws E, McCradden MD, Oakden-Rayner L, Pfohl SR, Ghassemi M, McKay F, Treanor D, Rostamzadeh N, Mateen B, Gath J, Adebajo AO, Kuku S, Matin R, Heller K, Sapey E, Sebire NJ, Cole-Lewis H, Calvert M, Denniston A, Liu X. The value of standards for health datasets in artificial intelligence-based applications. Nat Med. 2023 Nov;29(11):2929-2938.
55. Simcock IC, Shelmerdine SC, Hutchinson JC, Sebire NJ, Arthurs OJ. Body weight-based iodinated contrast immersion timing for human fetal postmortem microfocus computed tomography. BJR Open. 2023 Dec 12;6(1):tzad006.
56. Marques A, Matos C, Nikiphorou E, Livermore P et al. Towards a consensus for nurse education of methotrexate for people with rheumatic and musculoskeletal diseases: A scoping review. Musculoskeletal Care. 2023 Dec;21(4):1227-1237.
57. Pauling C, Kanber B, Arthurs OJ, Shelmerdine SC. Commercially available artificial intelligence tools for fracture detection: the evidence. BJR Open. 2023 Dec 12;6(1):tzad005.
    

Clinical Informatics Research Programme

1. Arthurs C, Roufosse C. Forging the tools for a computer-aided workflow in transplant pathology. Lancet Digit Health. 2022 Jan;4(1):e2-e3.
   
2. Shelmerdine S et al. Artificial intelligence in paediatric radiology: international survey of health care professionals' opinions. Pediatr Radiol. 2022 Jan;52(1):30-41.
3. Visram, S. Touchless Computing for Everyone. ITNOW. 2022, Feb 12, Vol 64 (1) 12-13.
   
4. Aggarwal R, Visram S, et al. Defining the Enablers and Barriers to the Implementation of Large-scale, Health Care-Related Mobile Technology: Qualitative Case Study in a Tertiary Hospital Setting. JMIR Mhealth Uhealth. 2022 Feb 8;10(2):e31497.
   
5. Pajaziti E, Milano EG, Schievano S, Cook A, Capelli C. Investigating the Feasibility of Virtual Reality for Teaching on Congenital Heart Disease. European Journal of Vascular and Endovascular Surgery. 2022 Feb 1;63(2):e42.
   
6. Dala-Ali B, Donnan L, Masterton G, Briggs L, Kauiers C, O'Sullivan M, Calder P, Eastwood DM. Osteofibrous dysplasia of the tibia: the importance of deformity in surveillance. Bone Joint J. 2022 Feb;104-B(2):302-308.
   
7. Yoshida M, Worlock KB, Huang N, Lindeboom RGH, Butler CR, Kumasaka N, Dominguez Conde C, Mamanova L, Bolt L, Richardson L, Polanski K, Madissoon E, Barnes JL, Allen-Hyttinen J, Kilich E, Jones BC, de Wilton A, Wilbrey-Clark A, Sungnak W, Pett JP, Weller J, Prigmore E, Yung H, Mehta P, Saleh A, Saigal A, Chu V, Cohen JM, Cane C, Iordanidou A, Shibuya S, Reuschl AK, Herczeg IT, Argento AC, Wunderink RG, Smith SB, Poor TA, Gao CA, Dematte JE; NU SCRIPT Study Investigators, Reynolds G, Haniffa M, Bowyer GS, Coates M, Clatworthy MR, Calero-Nieto FJ, Göttgens B, O'Callaghan C, Sebire NJ, Jolly C, De Coppi P, Smith CM, Misharin AV, Janes SM, Teichmann SA, Nikolić MZ, Meyer KB. Local and systemic responses to SARS-CoV-2 infection in children and adults. Nature. 2022 Feb;602(7896):321-327.
   
8. Issitt RW, Cortina-Borja M, Bryant W, Bowyer S, Taylor AM, Sebire N. Classification Performance of Neural Networks Versus Logistic Regression Models: Evidence From Healthcare Practice. Ruiz Nishiki M, Cabecinha M, Knowles R, Peters C, Aitkenhead H, Ifederu A, Schoenmakers N, Sebire NJ, Walker E, Hardelid P. Establishing risk factors and outcomes for congenital hypothyroidism with gland in situ using population-based data linkage methods: study protocol. BMJ Paediatr Open. 2022 Mar;6(1):e001341.
   
9. Hayes W, Laing E, Foley C, Pankhurst L, Thomas H, Hume-Smith H, Marks S, Kessaris N, Bryant WA, Spiridou A, Wray J, Peters MJ. Multicentre randomised controlled trial: protocol for Plasma-Lyte Usage and Assessment of Kidney Transplant Outcomes in Children (PLUTO). BMJ Open. 2022 Mar 14;12(3):e055595.
   
10. Issitt RW, Cortina-Borja M, Bryant W, Bowyer S, Taylor AM, Sebire N. Classification Performance of Neural Networks Versus Logistic Regression Models: Evidence From Healthcare Practice. Cureus. 2022 Feb 21;14(2):e22443.
    
11. Ruiz Nishiki M, Cabecinha M, Knowles R, Peters C, Aitkenhead H, Ifederu A, Schoenmakers N, Sebire NJ, Walker E, Hardelid P. Establishing risk factors and outcomes for congenital hypothyroidism with gland in situ using population-based data linkage methods: study protocol. BMJ Paediatr Open. 2022 Mar;6(1):e001341.
    
12. Chen Y, Harris S, Rogers Y, Ahmad T, Asselbergs FW. Nudging within learning health systems: next generation decision support to improve cardiovascular care. Eur Heart J. 2022 Mar 31;43(13):1296-1306.
    
13. Rowbotham NJ, Smith S, Davies G et al. Working in partnership with the patient community to develop outline trial designs in CF. J Cyst Fibros. 2022 Mar;21(2):300-301.
    
14. Neal SR, Zheng C. Covid‐19 through the lens of the peer‐reviewed literature. RSS Significance Magazine 2022.
    
15. Filipow N, Main E, Sebire NJ, Booth J, Taylor AM, Davies G, Stanojevic S. Implementation of prognostic machine learning algorithms in paediatric chronic respiratory conditions: a scoping review. BMJ Open Respir Res. 2022 Mar;9(1):e001165.
    
16. Wagner SK, Hughes F, Cortina-Borja M, Pontikos N, Struyven R, Liu X, Montgomery H, Alexander DC, Topol E, Petersen SE, Balaskas K, Hindley J, Petzold A, Rahi JS, Denniston AK, Keane PA. AlzEye: longitudinal record-level linkage of ophthalmic imaging and hospital admissions of 353 157 patients in London, UK. BMJ Open. 2022 Mar 16;12(3):e058552.
    
17. Vestesson E, Booth J, Hatcher J, McGarrity O, Sebire NJ, Steventon A, Suarez Alonso C, Tomlin S, Standing JF. The impact of the COVID-19 pandemic on antimicrobial prescribing at a specialist paediatric hospital: an observational study. J Antimicrob Chemother. 2022 Mar 31;77(4):1185-1188.
    
18. Fagan A, Arthurs OJ, Sebire NJ, Shelmerdine SC. Cinematic rendering of paediatric musculoskeletal pathologies: initial experiences with CT. Clin Radiol. 2022 Apr;77(4):274-282.
    
19. Klann JG, Strasser ZH, Hutch MR (4CE) et al. Distinguishing Admissions Specifically for COVID-19 From Incidental SARS-CoV-2 Admissions: National Retrospective Electronic Health Record Study. J Med Internet Res. 2022 May 18;24(5):e37931.
    
20. Vasey B, et al. DECIDE-AI expert group [S Shelmerdine] . Reporting guideline for the early-stage clinical evaluation of decision support systems driven by artificial intelligence: DECIDE-AI. Nat Med. 2022 May;28(5):924-933.
    
21. Vasey B, et al. DECIDE-AI expert group [S Shelmerdine]. Reporting guideline for the early stage clinical evaluation of decision support systems driven by artificial intelligence: DECIDE-AI. BMJ. 2022 May 18;377:e070904.
    
22. Gordon B, Fennessy C, Varma S, Barrett J, McCondochie E, Heritage T, Duroe O, Jeffery R, Rajamani V, Earlam K, Banda V, Sebire N. Evaluation of freely available data profiling tools for health data research application: a functional evaluation review. BMJ Open. 2022 May 9;12(5):e054186
    
23. Karamchandani U, Ahmed U, Rufai SR, Tan N, Tan W, Petrushkin H, Solebo AL. Long-term ocular and visual outcomes following symptomatic and asymptomatic congenital CMV infection: a systematic review protocol. BMJ Open. 2022 May 18;12(5):e059038.
    
24. AlBloushi AF, Solebo AL, Gokhale E, Hayouti H, Ajamil-Rodanes S, Petrushkin H. Long-Term Outcomes of Pediatric Idiopathic Intermediate Uveitis. Am J Ophthalmol. 2022 May;237:41-48.
    
25. Oldroyd AGS [Livermore P] et al. British Society for Rheumatology Standards, Audit and Guidelines Working Group. British Society for Rheumatology guideline on management of paediatric, adolescent and adult patients with idiopathic inflammatory myopathy. Rheumatology (Oxford). 2022 May 5;61(5):1760-1768.
    
26. Reicherts L, Rogers Y, Capra L et al. It's Good to Talk: A Comparison of Using Voice Versus Screen-Based Interactions for Agent-Assisted Tasks. ACM Trans. Comput. Hum. Interact. 29, 3, Article 25 (June 2022), 41 pages.
    
27. Weber GM, Consortium for Clinical Characterization of COVID-19 by EHR (4CE) et al. International comparisons of laboratory values from the 4CE collaborative to predict COVID-19 mortality. NPJ Digit Med. 2022 Jun 13;5(1):74.
    
28. Shelmerdine SC, White RD, Liu H, Arthurs OJ, Sebire NJ. Artificial intelligence for radiological paediatric fracture assessment: a systematic review. Insights Imaging. 2022 Jun 3;13(1):94.
    
29. Solebo AL, Kellett S, Rahi J Pediatric Ocular Inflammation UNICORN Study Group. et al. Development of a Nationally Agreed Core Clinical Dataset for Childhood Onset Uveitis. Front Pediatr. 2022 Jun 21;10:881398.
    
30. Hine C, Nilforooshan R, Barnaghi P. Ethical considerations in design and implementation of home-based smart care for dementia. Nurs Ethics. 2022 Jun;29(4):1035-1046.
    
31. Davies G. Does newborn screening improve early lung function in cystic fibrosis? Paediatr Respir Rev. 2022 Jun;42:17-22.
    
32. Majithia-Beet G, Naemi R, Issitt R. Efficacy of outcome prediction of the respiratory ECMO survival prediction score and the predicting death for severe ARDS on VV-ECMO score for patients with acute respiratory distress syndrome on extracorporeal membrane oxygenation. Perfusion. 2022 Jul 13:2676591221115267.
    
33. Kania SP, Silva JMF, Charles OJ, Booth J et al. Epstein-Barr Virus Reactivation After Paediatric Haematopoietic Stem Cell Transplantation: Risk Factors and Sensitivity Analysis of Mathematical Model. Front Immunol. 2022 Jul 12;13:903063.
    
34. Aguiar R, Bourmpaki E, Bunce C, Coker B, Delaney F, de Jongh L, Oliveira G, Weir A, Higgins F, Spiridou A et al. Incidence, Risk Factors, and Effect on Allograft Survival of Glomerulonephritis Post-transplantation in a United Kingdom Population: Cohort Study. Front Nephrol. 2022 Jul 14;2:923813.
    
35. Shivpuri A, Turtsevich I, Solebo AL, Compeyrot-Lacassagne S. Pediatric uveitis: Role of the pediatrician. Front Pediatr. 2022 Aug 1;10:874711.
    
36. Bowyer SA, Bryant WA, Key D, Booth J, Briggs L, Spiridou A, Cortina-Borja M, Davies G, Taylor AM, Sebire NJ. Machine learning forecasting for COVID-19 pandemic-associated effects on paediatric respiratory infections. Arch Dis Child. 2022 Aug 10:archdischild-2022-323822.
    
37. Walton S, Cortina-Borja M, Dezateux C, Griffiths LJ, Tingay K, Akbari A, Bandyopadhyay A, Lyons RA, Roberts R, Bedford H. Linking cohort data and Welsh routine health records to investigate children at risk of delayed primary vaccination. Vaccine. 2022 Aug 12;40(34):5016-5022.
    
38. Robertson AO, Horvat-Gitsels LA, Cortina-Borja M, Rahi JS. Distribution and associations of vision-related quality of life and functional vision of children with visual impairment. Br J Ophthalmol. 2022 Sep;106(9):1325-1330.
    
39. Peros T, Ricciardi F, Booth J, Ray S, Peters MJ. Evaluation of blood pressure trajectories and outcome in critically ill children with initial hypertension on admission to Paediatric Intensive Care. Anaesth Crit Care Pain Med. 2022 Sep 6;41(6):101149.
    
40. Solebo AL, Teoh L, Rahi JS; British Childhood Visual Impairment and Blindness Study Interest Group. The role of screening and surveillance in the detection of childhood vision impairment and blindness in the UK. Arch Dis Child. 2022 Sep;107(9):812-817.
    
41. Ganapathi S, Palmer J, Alderman JE, Calvert M, Espinoza C, Gath J, Ghassemi M, Heller K, Mckay F, Karthikesalingam A, Kuku S, Mackintosh M, Manohar S, Mateen BA, Matin R, McCradden M, Oakden-Rayner L, Ordish J, Pearson R, Pfohl SR, Rostamzadeh N, Sapey E, Sebire N, Sounderajah V, Summers C, Treanor D, Denniston AK, Liu X. Tackling bias in AI health datasets through the STANDING Together initiative. Nat Med. 2022 Sep 26.
    
42. Meshaka R, Pinto Dos Santos D, Arthurs OJ, Sebire NJ, Shelmerdine SC. Artificial intelligence reporting guidelines: what the pediatric radiologist needs to know. Pediatr Radiol. 2022 Oct;52(11):2101-2110.
    
43. Serban AI, Soreq E, Barnaghi P, Daniels S, Calvo RA; CR&T Group; Sharp DJ. The effect of COVID-19 on the home behaviours of people affected by dementia. NPJ Digit Med. 2022 Oct 17;5(1):154.
    
44. Kalantari E, Kouchaki S, Miaskowski C, Kober K, Barnaghi P. Network analysis to identify symptoms clusters and temporal interconnections in oncology patients. Sci Rep. 2022 Oct 12;12(1):17052.
    
45. Visram S, Mohamedally D, Roberts G, Hassan A, Kummen A, Chenuka Ratwatte C, Shaw R, Giuliani S, Taylor A, Connor J, Rafiq A, Sebire N and Rogers Y. UCL MotionInput: Touchless computing interactions in clinical training, radiology and operating theatres. Future Healthcare Journal 2022 Vol 9, No 3: 1–3.
    
46. Baker C, Xochicale M, Lin FY, Mathews S, Joubert F, Shakir DI, Miles R, Mosse CA, Zhao T, Liang W, Kunpalin Y, Dromey B, Mistry T, Sebire NJ, Zhang E, Ourselin S, Beard PC, David AL, Desjardins AE, Vercauteren T, Xia W. Intraoperative Needle Tip Tracking with an Integrated Fibre-Optic Ultrasound Sensor. Sensors (Basel). 2022 Nov 22;22(23):9035.
    
47. Aurora P, Duncan JA, Lum S, Davies G et al. London Cystic Fibrosis Collaboration (LCFC). Early Pseudomonas aeruginosa predicts poorer pulmonary function in preschool children with cystic fibrosis. J Cyst Fibros. 2022 Nov;21(6):988-995.
    
48. Tan BWL, Consortium for Clinical Characterization of COVID-19 by EHR (4CE). Long-term kidney function recovery and mortality after COVID-19-associated acute kidney injury: An international multi-centre observational cohort study. EClinicalMedicine. 2022 Nov 7;55:101724.
    
49. .Raies A, Tulodziecka E, Stainer J, et al. DrugnomeAI is an ensemble machine-learning framework for predicting druggability of candidate drug targets. Commun Biol. 2022 Nov 24;5(1):1291.
    
50. Gutiérrez-Sacristán A, Consortium for Clinical Characterization of COVID-19 by EHR (4CE). Hospitalizations Associated With Mental Health Conditions Among Adolescents in the US and France During the COVID-19 Pandemic. JAMA Netw Open. 2022 Dec 1;5(12):e2246548.
    
51. Meshaka R, Laidlow-Singh H, Langan D, Arthurs OJ, Shelmerdine SC. Presentation to publication: Changes in paediatric radiology research trends 2010-2016. Pediatr Radiol. 2022 Dec;52(13):2538-2548.
    
52. Shelmerdine S et al. FRCR-AI Study Collaborators. Can artificial intelligence pass the Fellowship of the Royal College of Radiologists examination? Multi-reader diagnostic accuracy study. BMJ. 2022 Dec 21;379:e072826.
    
53. Jefferson E, Cole C, Mumtaz et al. A Hybrid Architecture (CO-CONNECT) to Facilitate Rapid Discovery and Access to Data Across the United Kingdom in Response to the COVID-19 Pandemic: Development Study. J Med Internet Res. 2022 Dec 27;24(12):e40035.
    
54. Soreq E, Kolanko MA, Monica CD, Ravindran KKG, Revell VL, de Villèle P, Barnaghi P, Dijk DJ, Sharp DJ; CRT group. Monitoring abnormal nocturnal behaviour in the homes of patients living with dementia. Alzheimers Dement. 2022 Dec;18 Suppl 2:e067936.
    
55. Kolanko MA, Soreq E, Lai H, Barnaghi P, Dijk DJ, Sharp DJ. Clinically relevant monitoring of long-term night-time behaviour and physiology from the homes of people living with dementia. Alzheimers Dement. 2022 Dec;18 Suppl 2:e068241.
    
56. Belitsis G, Pajaziti E, Schievano S, Capelli C, Cook A, Kostolny M. Use of virtual reality in complex double outlet right ventricle cases. Multimedia Manual of Cardiothoracic Surgery: MMCTS. 2022 Dec 12;2022

Clinical Informatics Research Programme

1. Kummen A, Li G, Hassan A, Ganeva T, Lu Q, Shaw R, Ratwatte C, Zou Y, Han L, Almazov E, Visram S, Taylor A, Sebire NJ, Stott L, Rogers Y, Roberts G, Mohamedally D. MotionInput v2.0 supporting DirectX: A modular library of open-source gesture-based machine learning and computer vision methods for interacting and controlling existing software with a webcam. arXiv.org
   
2. Issitt R, Crook R, Shaw M, Robertson A. The Great Ormond Street Hospital immunoadsorption method for ABO-incompatible heart transplantation: a practical technique. Perfusion. 2021 Jan;36(1):34-37.
   
3. Davendralingam N, Sebire NJ, Arthurs OJ, Shelmerdine SC. Artificial intelligence in paediatric radiology: Future opportunities. Br J Radiol. 2021 Jan 1;94(1117):20200975.
   
4. Cernile G, Heritage T, Sebire NJ, Gordon B, Schwering T, Kazemlou S, Borecki Y. Network graph representation of COVID-19 scientific publications to aid knowledge discovery. BMJ Health Care Inform. 2021 Jan;28(1):e100254.
   
5. Khan SM, Liu X, Nath S, Korot E, Faes L, Wagner SK, Keane PA, Sebire NJ, Burton MJ, Denniston AK. A global review of publicly available datasets for ophthalmological imaging: barriers to access, usability, and generalisability. Lancet Digit Health. 2021 Jan;3(1):e51-e66.
   
6. Weber GM, Consortium for Clinical Characterization of COVID-19 by EHR (4CE) et al. International Comparisons of Harmonized Laboratory Value Trajectories to Predict Severe COVID-19: Leveraging the 4CE Collaborative Across 342 Hospitals and 6 Countries: A Retrospective Cohort Study. medRxiv [Preprint]. 2021 Feb 5:2020.12.16.20247684.
   
7. Johal N, Cao K, Arthurs C, Millar M, Thrasivoulou C, Ahmed A, Jabr RI, Wood D, Cuckow P, Fry CH. Contractile function of detrusor smooth muscle from children with posterior urethral valves - The role of fibrosis. J Pediatr Urol. 2021 Feb;17(1):100.e1-100.e10.
   
8. Almossawi O, Friend A, Palla L, Feltbower R, De Stavola B. Is there a sex difference in mortality rates for deaths occurring in paediatric intensive care units? Systematic literature review protocol. BMJ Open. 2021 Feb 5;11(2):e046794.
   
9. Hall GL, Filipow N, et al. Official ERS technical standard: Global Lung Function Initiative reference values for static lung volumes in individuals of European ancestry. Eur Respir J. 2021 Mar 11 57(3):2000289.
   
10. Neijenhuis RML, Tsang VT, Marek J, Issitt R et al. Cone reconstruction for Ebstein anomaly: Late biventricular function and possible remodeling. J Thorac Cardiovasc Surg. 2021 Mar;161(3):1097-1108.
    
11. Du-Harpur X, Arthurs C et al. Clinically Relevant Vulnerabilities of Deep Machine Learning Systems for Skin Cancer Diagnosis. J Invest Dermatol. 2021 Apr;141(4):916-920.
    
12. Shelmerdine SC, Sebire NJ, Calder AD, Arthurs OJ. Three-dimensional cinematic rendering of fetal skeletal dysplasia using postmortem computed tomography. Ultrasound Obstet Gynecol. 2021 Apr;57(4):659-660.
    
13. Firouzi F, Farahani B, Daneshmand M, Grise K, Song J, Saracco R, Wang LL, Lo K, Angelov P, Soares E, Loh PS, Talebpour Z, Moradi R, Goodarzi M, Ashraf H, Talebpour M, Talebpour A, Romeo L, Das R, Heidari H, Pasquale D, Moody J, Woods C, Huang ES, Barnaghi P, Sarrafzadeh M, Li R, Beck KL, Isayev O, Sung N, Luo A. Harnessing the Power of Smart and Connected Health to Tackle COVID-19: IoT, AI, Robotics, and Blockchain for a Better World. IEEE Internet Things J. 2021 Apr 19;8(16):12826-12846.
    
14. Gordon B, Barrett J, Fennessy C, Cake C, Milward A, Irwin C, Jones M, Sebire N. Development of a data utility framework to support effective health data curation. BMJ Health Care Inform. 2021 May;28(1):e100303.
    
15. Bourgeois FT, Gutiérrez-Sacristán A, Keller MS et al. Consortium for Clinical Characterization of COVID-19 by EHR (4CE). International Analysis of Electronic Health Records of Children and Youth Hospitalized With COVID-19 Infection in 6 Countries. JAMA Netw Open. 2021 Jun 1;4(6):e2112596.
    
16. Arzanauskaite M, Shelmerdine S et al. Academia in cardiovascular radiology: are we doing enough for the future of the subspecialty? Clin Radiol. 2021 Jul;76(7):502-509.
    
17. Shelmerdine S et al. A pragmatic evidence-based approach to post-mortem perinatal imaging. Insights Imaging. 2021 Jul 15;12(1):101.
    
18. Penner J, Abdel-Mannan O, Grant K, GOSH PIMS-TS MDT Group et al. 6-month multidisciplinary follow-up and outcomes of patients with paediatric inflammatory multisystem syndrome (PIMS-TS) at a UK tertiary paediatric hospital: a retrospective cohort study. Lancet Child Adolesc Health. 2021 Jul;5(7):473-482.
    
19. Langan D, Shelmerdine S, Taylor A, Bryant WA, Booth J, Sebire NJ, Arthurs O, Cortina-Borja M. Impact of the COVID-19 pandemic on radiology appointments in a tertiary children's hospital: a retrospective study. BMJ Paediatr Open. 2021 Aug 11;5(1):e001210.
    
20. Visram S, Potts L, Sebire NJ, Rogers Y, Broughton E, Chigaru L, Nambyiah P. Making the invisible visible: New perspectives on the intersection of human-environment interactions of clinical teams in intensive care. J Perinatol. 2022 Apr;42(4):503-504.
    
21. Booth J, Margetts B, Bryant W, Issitt R, Hutchinson C, Martin N, Sebire NJ. Machine Learning Approaches to Determine Feature Importance for Predicting Infant Autopsy Outcome. Pediatr Dev Pathol. 2021 Jul-Aug;24(4):351-360.
    
22. Filipow N, Davies G, Main E, Sebire NJ, Wallis C, Ratjen F, Stanojevic S. Unsupervised phenotypic clustering for determining clinical status in children with cystic fibrosis. Eur Respir J. 2021 Aug 5;58(2):2002881.
    
23. Channon-Wells S, Kwok M, Booth J et al. The use of continuous electronic prescribing data to infer trends in antimicrobial consumption and estimate the impact of stewardship interventions in hospitalized children. J Antimicrob Chemother. 2021 Aug 12;76(9):2464-2471.
    
24. Pajaziti E, Schievano S, Sauvage E, Cook A, Capelli C. Investigating the feasibility of virtual reality (VR) for teaching cardiac morphology. Electronics. 2021 Aug 6;10(16):1889.
    
25. Shelmerdine S et al. Review of study reporting guidelines for clinical studies using artificial intelligence in healthcare. BMJ Health Care Inform. 2021 Aug;28(1):e100385.
    
26. Li H, Barnaghi P, Enshaeifar S, Ganz F. Continual Learning Using Bayesian Neural Networks. IEEE Trans Neural Netw Learn Syst. 2021 Sep;32(9):4243-4252.
    
27. Estiri H, Consortium for Clinical Characterization of COVID-19 by EHR (4CE) et al. Evolving phenotypes of non-hospitalized patients that indicate long COVID. BMC Med. 2021 Sep 27;19(1):249.
    
28. Stanojevic S, Cooper B, Filipow N et al. Reply to: When adopting Global Lung Function Initiative reference values, can we also adapt them to a local context as needed? Eur Respir J. 2021 Sep 16; 58(3):2102020.
    
29. Arthurs C, Ahmed A. QuArray: an application for tissue array whole slide image export and signal analysis. Bioinformatics. 2021 Sep 29;37(18):3082-3083.
    
30. Le TT, Consortium for Clinical Characterization of COVID-19 by EHR (4CE) et al. Multinational characterization of neurological phenotypes in patients hospitalized with COVID-19. Sci Rep. 2021 Oct 12;11(1):20238.
    
31. Lai AG, Chang WH, Parisinos CA, Katsoulis M, Blackburn RM, Shah AD, Nguyen V, Denaxas S, Davey Smith G, Gaunt TR, Nirantharakumar K, Cox MP, Forde D, Asselbergs FW, Harris S, Richardson S, Sofat R, Dobson RJB, Hingorani A, Patel R, Sterne J, Banerjee A, Denniston AK, Ball S, Sebire NJ, Shah NH, Foster GR, Williams B, Hemingway H. An informatics consult approach for generating clinical evidence for treatment decisions. BMC Med Inform Decis Mak. 2021 Oct 12;21(1):281.
    
32. Weber GM, Zhang HG, L'Yi S et al. Consortium For Clinical Characterization Of COVID-19 By EHR (4CE), Kohane IS, Cai T, South AM, Brat GA. International Changes in COVID-19 Clinical Trajectories Across 315 Hospitals and 6 Countries: Retrospective Cohort Study. J Med Internet Res. 2021 Oct 11;23(10):e31400.
    
33. Akintomide E, Shah B, Sridharan S, Visram S, Sebire NJ, Peters C. Clinical perception of effectiveness of virtual appointments and comparison with appointment outcomes at a specialist children’s hospital. Future Healthcare Journal, 2021. Nov Vol 8, No 3: e660–5.
    
34. Almossawi O, O'Brien S, Parslow R, Nadel S, Palla L. A study of sex difference in infant mortality in UK pediatric intensive care admissions over an 11-year period. Sci Rep. 2021 Nov 8;11(1):21838.
    
35. Sridharan S, Peters C, Newcombe S, Jephson C, Robinson R, Mulder B, Houghton W, Visram S, Sebire NJ. The essence of healthcare records: embedded electronic health record system microblogging functionality for patient care narrative. Future Healthc J. 2021 Nov; 8(3):e709-e713.
37. Issitt R, Booth J, Crook R Robertson A, Molyneux V, Richardson R, Cross N, Shaw M, Tsang V, Muthurangu V, Sebire NJ, Burch M, Fenton M. Intraoperative anti-A/B immunoadsorption is associated with significantly reduced blood product utilization with similar outcomes in pediatric ABO-incompatible heart transplantation. J Heart Lung Transplant. 2021 Nov;40(11):1433-1442.
    
38. Cushnan D, Berka R, Bertolli O, Williams P, Schofield D, Joshi I, Favaro A, Halling-Brown M, Imreh G, Jefferson E, Sebire NJ, Reilly G, Rodrigues JCL,Cushnan D, Berka R, Bertolli O et al. Towards nationally curated data archives for clinical radiology image analysis at scale: Learnings from national data collection in response to a pandemic. Digit Health. 2021 Nov 23;7:20552076211048654.
    
39. Dobra R, Davies G et al. London Network of Clinical Trials Accelerator Platform sites and affiliates. Optimising equity of access: how should we allocate slots to the most competitive trials in Cystic Fibrosis (CF)? J Cyst Fibros. 2021 Nov;20(6):978-985.
    
40. Owen E, Williams JE, Davies G et al. Growth, Body Composition, and Lung Function in Prepubertal Children with Cystic Fibrosis Diagnosed by Newborn Screening. Nutr Clin Pract. 2021 Dec;36(6):1240-1246.
    
41. Milano EG, Kostolny M, Pajaziti E, Marek J, Regan W, Caputo M, Luciani GB, Mortensen KH, Cook AC, Schievano S, Capelli C. Enhanced 3D visualization for planning biventricular repair of double outlet right ventricle: a pilot study on the advantages of virtual reality. European Heart Journal-Digital Health. 2021 Dec 1;2(4):667-75.
    
42. Fletcher-Lloyd N, Soreq E, Wilson D, Nilforooshan R, Sharp DJ, Barnaghi P. Home monitoring of daily living activities and prediction of agitation risk in a cohort of people living with dementia. Alzheimers Dement. 2021 Dec;17 Suppl 12:e058614.
    
43. Amerineni R, Gupta L, Steadman N, Annauth K, Burr C, Wilson S, Barnaghi P, Vaidyanathan R. Fusion Models for Generalized Classification of Multi-Axial Human Movement: Validation in Sport Performance. Sensors (Basel). 2021 Dec 16;21(24):8409.

Clinical Informatics Research Programme

1. Milano EG, Pajaziti E, Schievano S, Cook A, Capelli C. P369 Patient specific virtual reality for education in congenital heart disease. European Heart Journal-Cardiovascular Imaging. 2020 Jan 1;21(Supplement_1):jez319-218.
   
2. Maneas E, Aughwane R, Huynh N, Xia W, Ansari R, Kuniyil Ajith Singh M, Hutchinson JC, Sebire NJ, Arthurs OJ, Deprest J, Ourselin S, Beard PC, Melbourne A, Vercauteren T, David AL, Desjardins AE. Photoacoustic imaging of the human placental vasculature. J Biophotonics. 2020. Apr;13(4):e201900167.
   
3. Banerjee A, Pasea L, Harris S, Gonzalez-Izquierdo A, Torralbo A, Shallcross L, Noursadeghi M, Pillay D, Sebire N, Holmes C, Pagel C, Wong WK, Langenberg C, Williams B, Denaxas S, Hemingway H. Estimating excess 1-year mortality associated with the COVID-19 pandemic according to underlying conditions and age: a population-based cohort study. Lancet. 2020. May 30;395(10238):1715-1725.
   
4. Wiggins LM, Mimic B, Issitt R, Ilic S, Bonello B, Marek J, Kostolny M. The utility of aortic valve leaflet reconstruction techniques in children and young adults. J Thorac Cardiovasc Surg. 2020 Jun;159(6):2369-2378.
   
5. Sebire NJ, Cake C, Morris AD. HDR UK supporting mobilising computable biomedical knowledge in the UK. BMJ Health Care Inform. 2020. Jul;27(2):e100122.
   
6. Crook R, Issitt R. Cardiopulmonary Bypass for a Patient With Congenital Hyperinsulinemia. World J Pediatr Congenit Heart Surg. 2020 Jul;11(4):NP117-NP119.
   
7. Issitt RW, Booth J, Bryant WA, Spiridou A, Taylor AM, du Pré P, Pad Ramnarayan P, Hartley J, Cortina-Borja M, Moshal K, Dunn H, Hemingway H, and Sebire NJ. Children with COVID-19 at a specialist centre: initial experience and outcome. Lancet Child Adolesc Health 2020. Aug;4(8):e30-e31.
   
8. Jacob J, Alexander D, Baillie JK, Berka R, Bertolli O, Blackwood J, Buchan I, Bloomfield C, Cushnan D, Docherty A, Edey A, Favaro A, Gleeson F, Halling-Brown M, Hare S, Jefferson E, Johnstone A, Kirby M, Mcstay R, Nair A, Openshaw PJM, Parker G, Reilly G, Robinson G, Roditi G, Rodrigues JCL, Sebire N, Semple MG, Sudlow C, Woznitza N, Joshi I. Using imaging to combat a pandemic: rationale for developing the UK National COVID-19 Chest Imaging Database. Eur Respir J. 2020. Aug 13;56(2):2001809.
   
9. Goldacre B, Bardsley M, Benson T, Cheema K, Chinn R, Coughlan E, Dougan S, Farr M, Hawkins L, Jonas A, Kinnear A, Mcinnes M, Mohammed MA, Morton C, Pasumarthy R, Pettinger N, Rowland B, Sebire N, Stroner P, Tennison J, Warnakula S, Watson O, Wright E, Young H, Morley J. NHS data analysis into the 21st century. J R Soc Med. 2020. Oct;113(10):383-388.
   
10. Stanojevic S, Filipow N, Ratjen F. Pediatric Reproducibility Limits for the Forced Expiratory Volume in 1 second Thorax 2020. Oct;75(10):891-896.
    
11. Visram S, Hussain W, Goddard A. Towards future healthcare that is digital by default. Future Healthc J. 2020. Oct;7(3):180.
    
12. Raywood E, Douglas H, Kapoor K, Filipow N, Murray N, Connor R, Stott L, Saul G, Kuzhagaliyev T, Davies G, Liakhovich O, Van Schaik T, Furtuna B, Booth J, Shannon H, Bryon M, Main E. Protocol for Project Fizzyo, an analytic longitudinal observational cohort study of physiotherapy for children and young people with cystic fibrosis, with interrupted time-series design. BMJ Open, 2020 Oct 7;10(10):e039587.
    
13. Toescu, S.M., Samarth, G., Horsfall, H.L., Issitt, R., Margetts, B., Phipps, K., Jeelani, N.O., Thompson, D.N.P., Aquilina, K. Fourth ventricle tumours in children – complications and influence of surgical approach. J Neurosurg Pediatr. 2020 Oct 23;27(1):52-61.

Clinical Informatics Research Programme

1. Boonsathorn S, Cheng I, Kloprogge F, Alonso C, Lee C, Doncheva B, Booth J, Chiesa R, Irwin A, Standing JF. Clinical Pharmacokinetics and Dose Recommendations for Posaconazole in Infants and Children. Clin Pharmacokinet. 2019. Jan;58(1):53-61.
   
2. Enshaeifar S, Zoha A, Skillman S, Markides A, Acton ST, Elsaleh T, Kenny M, Rostill H, Nilforooshan R, Barnaghi P. Machine learning methods for detecting urinary tract infection and analysing daily living activities in people with dementia. PLoS One. 2019. Jan 15;14(1):e0209909.
   
3. Papachristou N, Barnaghi P, Cooper B, Kober KM, Maguire R, Paul SM, Hammer M, Wright F, Armes J, Furlong EP, McCann L, Conley YP, Patiraki E, Katsaragakis S, Levine JD, Miaskowski C. Network Analysis of the Multidimensional Symptom Experience of Oncology. Sci Rep. 2019. Feb 19;9(1):2258.
   
4. Kloprogge F, Hill LF, Booth J, Klein N, Irwin AD, Dixon G, Standing JF. Revising Pediatric Vancomycin Dosing Accounting for Nephrotoxicity in a Pharmacokinetic-Pharmacodynamic Model. Antimicrob Agents Chemother. 2019. Apr 25;63(5):e00067-19.
   
5. Adalat S, Hayes WN, Bryant WA, Booth J, Woolf AS, Kleta R, Subtil S, Clissold R, Colclough K, Ellard S, Bockenhauer D. HNF1B Mutations Are Associated With a Gitelman-like Tubulopathy That Develops During Childhood. Kidney Int Rep. 2019 May 29;4(9):1304-1311.
   
6. Hayes W, Longley C, Scanlon N, Bryant W, Stojanovic J, Kessaris N, Van't Hoff W, Bockenhauer D, Marks SD. Plasma electrolyte imbalance in pediatric kidney transplant recipients. Pediatr Transplant. 2019. Jun;23(4):e13411.
   
7. Lim B, Rogers Y, and Sebire N. Designing to Distract: Can Interactive Technologies Reduce Visitor Anxiety in a Children’s Hospital Setting? ACM Trans. Comput. Hum. Interact. 2019.
   
8. Shelmerdine SC, Singh M, Norman W, Jones R, Sebire NJ, Arthurs OJ. Automated data extraction and report analysis in computer-aided radiology audit: practice implications from post-mortem paediatric imaging. Clin Radiol. 2019. Sep;74(9):733.e11-733.e18.
   
9. Palee P, Sharp B, Noriega L, Sebire N, Platt C. Heuristic neural network approach in histological sections detection of hydatidiform mole. J Med Imaging (Bellingham). 2019. Oct;6(4):044501.
   
10. Priestman W, Collins R, Vigne H, Sridharan S, Seamer L, Bowen D, Sebire NJ. Lessons learned from a comprehensive electronic patient record procurement process-implications for healthcare organisations. BMJ Health Care Inform. 2019. May;26(1):e000020.
    
11. Matthews, P. Blair, S. Sisodiya, S. Jones, N. Sebire, E. Behr, P. Fleming. National registry for sudden unexpected deaths of infants and children in England: why do we need one and do families want one? Arch Dis Child. 2019 Oct;104(10):989-993.

Clinical Informatics Research Programme

1. Richardson R, Issitt R, Crook R. Beta-thalassemia in the paediatric cardiac surgery setting - a case report and literature review. Perfusion. 2018. Apr;33(3):232-234.
   
2. Robertson A, Issitt R, Crook R, Gustafsson K, Eddaoudi A, Tsang V, Burch M. A novel method for ABO-incompatible heart transplantation. J Heart Lung Transplant. 2018 Apr;37(4):451-457.
   
3. Gkazi AS, Margetts BK, Attenborough T, Mhaldien L, Standing JF, Oakes T, Heather JM, Booth J, Pasquet M, Chiesa R, Veys P, Klein N, Chain B, Callard R, Adams SP. Clinical T Cell Receptor Repertoire Deep Sequencing and Analysis: An Application to Monitor Immune Reconstitution Following Cord Blood Transplantation. Front Immunol. 2018. Nov 5;9:2547.
   
4. Priestman W, Sridharan S, Vigne H, Collins R, Seamer L, Sebire NJ. What to expect from electronic patient record system implementation; lessons learned from published evidence. J Innov Health Inform. 2018
   
5. Sridharan S, Priestman W, Sebire NJ. Chief Information Officer team evolution in university hospitals: interaction of the three 'C's (CIO, CCIO, CRIO). J Innov Health Inform. 2018.