When a baby or child has gastro-oesophageal reflux, the food and drink travels down the foodpipe as normal. However, some of the mixture of food, drink and acid travels back up the foodpipe, instead of passing through to the large and small intestines. As the food and drink is mixed with acid from the stomach, it can irritate the lining of the foodpipe, making it sore. This is gastro-oesophageal reflux disease.
X-linked inhibitor of apoptosis protein (XIAP) deficiency is a rare, inherited immunodeficiency that occurs almost exclusively in boys. Sometimes it is called X-linked lymphoproliferative type 2 disorder (XLP2). This page has been produced jointly between PID UK, Great Ormond Street Hospital (GOSH) and the Great North Children’s Hospital.
X-linked lymphoproliferative type 1 (XLP1) disorder is a rare immune condition that affects around 1 in every 1 million males.This page has been produced jointly between PID UK, Great Ormond Street Hospital (GOSH) and the Great North Children’s Hospital.
Beckwith-Wiedemann syndrome (BWS) is a congenital (present at birth) overgrowth syndrome that occurs in approximately one in 15,000 births. This information from Great Ormond Street Hospital (GOSH) explains the causes, symptoms and treatment of BWS and where to get help.
This information from Great Ormond Street Hospital (GOSH) is about pectus excavatum (also known as funnel chest). Pectus excavatum is a condition in which, instead of being level with the ribs, the breastbone (sternum) is ‘sunken’ so that the middle of the chest looks ‘caved in’.
Henoch Schönlein purpura (HSP) is a disease where small blood vessels called capillaries become inflamed and damaged, producing a rash on the skin called ’purpura’. This information sheet from Great Ormond Street Hospital (GOSH) explains about Henoch Schönlein purpura (HSP), what causes it and how it can be treated. It also gives details of what to expect when your child has assessment and treatment.