Lymphocyte subsets V beta repertoire

EPIC

V beta repertoire

Section

Immunology

Clinical indications

Looks at surface expression of T cell receptor V beta families. In normal individuals at least 70 % of their T cells will be detected with the panel of antibodies used, and there will be a polyclonal distribution. Oligoclonal expansions on a polyclonal background are suggestive of infection or malignancy, whilst an oligoclonal distribution is seen in defects of T cell development

Specimen requirement

1mls EDTA

Dispatch and handling instructions

Samples should be less than 24 hours old and arrive before 2pm on a Friday

Turnaround time

8 days

Synonym

Not applicable

Is it IS0 15189 accredited?

Yes