Congenital Hyperinsulinism (CHI)

Welcome to the homepage for Congenital Hyperinsulinism (CHI) at Great Ormond Street Hospital (GOSH).

Congenital Hyperinsulinism International Center of Excellence Logo

In June 2021, GOSH's CHI department was recognised as one of six centres of international excellence.

Congenital Hyperinsulinism (CHI) is a very complex medical condition that presents with severe hypoglycaemia (low blood glucose) in the neonatal, infancy and childhood period. The congenital hyperinsulinism centre at Great Ormond Street Children's Hospital NHS Trust has treated over 700 patients and is a national and international referral centre for patients from as far as India and Malaysia. 

We have a dedicated and committed multidisciplinary team to deliver the best care possible to these highly complicated patients. Combined with our high class clinical service we have developed cutting edge translational research to understand the genetic basis of congenital hyperinsulinism.

Watch our short video which outlines the mechanism of Congenital Hyperinsulinism and how it affects the blood glucose levels.

Meet our team

Learn more about the different roles within the CHI team.

Patient stories

Parents of GOSH patients share their experiences of hyperinsulinism.

Contact us

Details on how to contact the CHI team

at GOSH.

Parent support groups

Access support groups' details who provide families of children with Congenital Hyperinsulinism with key resources and information.