Research and publications

We have an active research programme and regularly present our work at national and international conferences and publish original articles in peer-reviewed scientific journals. We also aim to educate and have published book chapters on Urolithiasis.

Peer-reviewed Publications:

Verhagen MV, Watson TA, Hickson M, Smeulders N, Humphries PD. Pediatr Radiol. 2019 May;49(6):777-783. doi: 10.1007/s00247-019-04372-x.

Thomas JS, Smeulders N, Yankovic F, Undre S, Mushtaq I, López PJ, Cuckow P. J Pediatr Urol. 2018 Oct;14(5):433.e1-433.e4. doi: 10.1016/j.jpurol.2018.02.024.

  • Epidemiology of paediatric renal stone disease: a 22-year single centre experience in the UK

Issler N, Dufek S, Kleta R, Bockenhauer D, Smeulders N, Van't Hoff W. BMC Nephrol. 2017 Apr 18;18(1):136. doi: 10.1186/s12882-017-0505-x.

Mendichovszky I, Solar BT, Smeulders N, Easty M, Biassoni L. Semin Nucl Med. 2017 May;47(3):204-228. doi: 10.1053/j.semnuclmed.2016.12.002.

  • A randomised Phase I/II trial to evaluate the efficacy and safety of orally administered Oxalobacter formigenes to treat primary hyperoxaluria.

Hoppe B, Niaudet P, Salomon R, Harambat J, Hulton SA, Van't Hoff W, Moochhala SH, Deschênes G, Lindner E, Sjögren A, Cochat P. Pediatr Nephrol. 2017 May;32(5):781-790. doi: 10.1007/s00467-016-3553-8.

  • An institutional experience of pre-emptive liver transplantation for pediatric primary hyperoxaluria type 1.

Khorsandi SE, Samyn M, Hassan A, Vilca-Melendez H, Waller S, Shroff R, Koffman G, Van't Hoff W, Baker A, Dhawan A, Heaton N. Pediatr Transplant. 2016 Jun;20(4):523-9. doi: 10.1111/petr.12705.

Mathers J, Solar BT, Harding L, Smeulders N, Hume-Smith H. Urology. 2015 Nov;86(5):1008-12. doi: 10.1016/j.urology.2015.07.017.

Yankovic F, Swartz R, Cuckow P, Hiorns M, Marks SD, Cherian A, Mushtaq I, Duffy P, Smeulders N. J Pediatr Urol. 2013 Dec;9(6 Pt A):820-4. doi: 10.1016/j.jpurol.2012.10.025. Epub 2012 Nov 24.

  • The enzyme 4-hydroxy-2-oxoglutarate aldolase is deficient in primary hyperoxaluria type 3.

Williams EL, Bockenhauer D, Van't Hoff WG, Johri N, Laing C, Sinha MD, Unwin R, Viljoen A, Rumsby G. Nephrol Dial Transplant. 2012 Aug;27(8):3191-5. doi: 10.1093/ndt/gfs039. Epub 2012 Mar 5.

  • Primary cultures of renal tubule cells derived from individuals with primary hyperoxaluria.

Price KL, Hulton SA, Van't Hoff WG, Masters JR, Rumsby G. Urol Res. 2009 Jun;37(3):127-32.

  • Epidemiology of paediatric renal stone disease in the UK.

Coward RJM, Peters CJ, Duffy PG, Corry D, Kellett MJ, Choong S, van't Hoff WG. Arch Dis Child 2003;88:962-965

  • The management of paediatric urolithiasis

Choong S, Whitfield H, Duffy P, Kellett M, Cuckow P, Van't Hoff W, Corry D. BJU Int 2000 Nov;86(7):857-60