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Genetic study of over 1,000 people sheds new light on immune-system disorders

Whole Genome Sequencing (WGS) can provide a more accurate diagnosis for patients with missing or poorly functioning immune systems, while providing new insight into complex genetic causes, according to results of a new international study involving researchers from the UCL Great Ormond Street Institute of Child Health (ICH).

Propranolol

Propranolol belongs to a group of drugs called beta blockers. It is used in patients with heart problems to control high blood pressure or irregular heart beats.This information sheet describes how this medicine is given and some of its possible side effects.

Visiting GOSH for an outpatient appointment during the coronavirus (COVID-19) pandemic

We understand that you might be worried about coronavirus – also known as COVID-19. This information sheet from the Outpatient Department explains what to expect when you come to an appointment. Please read this alongside our general FAQs for families at gosh.nhs.uk/covid-19-FAQ. You can also find the latest news, information and resources in our COVID-19 information hub at gosh.nhs.uk/coronavirus-hub.

Colonic transit (pellet) study

A colonic transit study is a test that shows how quickly food passes through the digestive system. This may also be called a pellet study.  It starts when you give your child some pellets to swallow on three consecutive days. On the fourth day, they will need to come into hospital for an x-ray. If there are some pellets seen on this x-ray you might be asked to return for a second x-ray on day 6. This information sheet from Great Ormond Street Hospital (GOSH) explains about the transit study test and what to expect when your child has one.

Collecting a urine sample

Urine is a waste product produced by the kidneys, so testing it can show if the kidneys are not working well. Testing a urine sample is usually the first stage in carrying out a general assessment, before blood tests are needed. This information sheet from Great Ormond Street Hospital (GOSH) explains how to collect a clean urine sample for testing.

Actikerall® to treat warts

Actikerall® is a clear solution to be applied to the affected area of skin – 1g of Actikerall® contains 5mg fluoroucil, which destroys some skin cells and 100mg salicylic acid, which makes skin shed more easily. Its full name is Actikerall® 5mg/g + 100mg/g cutaneous solution.