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GOSH research patient in the Somers Clinical Research Facility (CRF)

Taking part in a trial to transform treatment

Alice, age 11, took part in a clinical trial to evaluate the efficacy of the drug tocilizumab for children with systemic Juvenile Idiopathic Arthritis (sJIA). Results from the trial led to tocilizumab being licensed, which will transform the long-term health of children, like Alice, with sJIA. Alice and her mum, Nerys, tell us about their experience of taking part in the trial at Great Ormond Street Hospital (GOSH).

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Department of Orthopaedic and Spine Surgery

PLEASE NOTE in the light of the current coronavirus (COVID-19) situation, the Haemodialysis team has created a handy guidance FAQ document available below:

Coronavirus (COVID-19) – information for children, young people and families from the Orthopaedics team (242.09 KB)

Welcome to the Department of Orthopaedic and Spine Surgery

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Services provided by the Occupational Therapy department

The Occupational Therapy team offers a tertiary level service at Great Ormond Street Hospital. Occupational therapy is available in a number of clinical areas to both inpatients and outpatients. The occupational therapists liaise with community therapy teams to address patients' ongoing needs and to ensure continued care.

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Methotrexate for chronic inflammatory conditions

Methotrexate is a medicine that has been used to treat chronic inflammatory conditions such as juvenile idiopathic arthritis, juvenile dermatomyositis, systemic lupus erythematosus, vasculitis and severe psoriasis for many years.This information sheet from Great Ormond Street Hospital (GOSH) explains about the use of methotrexate in such conditions.

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New research centre for teenagers with arthritis

The world’s first research centre dedicated to understanding how and why arthritis affects teenagers has opened in the UK.

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Cutting edge new method reveals novel cause of Juvenile dermatomyositis

A new in-depth method has helped shed light on the key role of B cells, a type of immune cell, in the rare childhood condition Juvenile dermatomyositis (JDM).

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Research and publications from the Ophthalmology department

Our clinical research programmes benefit from the input of clinicians and scientists across many disciplines.

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UK-wide consortium to transform treatment for children and young people with arthritis and uveitis

Researchers from the UCL Great Ormond Street Institute of Child Health (ICH) and Great Ormond Street Hospital (GOSH) will lead a UK-wide effort to drive the development of new, targeted treatments for children and young people with juvenile idiopathic arthritis (JIA) and its associated eye-inflammation condition, uveitis.

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About the Physiotherapy department

Physiotherapy is the assessment and treatment of conditions through physical means.

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Conditions treated by the Infectious Diseases department

The Great Ormond Street Hospital (GOSH) Infectious Diseases department provides clinical expertise in the diagnosis and management of unusual and complicated infections, tropical diseases and children with HIV infection and AIDS.

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BRC Doctoral Training Support Fund awards

CLOSED. Research students were invited to apply to the Doctoral Training Support Fund for funding to support the running costs for translational clinical research/experimental medicine projects being undertaken within GOSH and ICH.

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Physiotherapy student placements

Physiotherapy placements are in high demand so you should apply early to avoid disappointment.

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NIHR GOSH BRC PhD Studentships - October 2019

CLOSED: The National Institute of Health Research (NIHR) Biomedical Research Centre at Great Ormond Street Hospital (GOSH BRC) are seeking applications from students wishing to undertake a PhD with an emphasis on translational research and child health.

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Conditions treated by the Orthopaedic and Spine Surgery Department

The Orthopaedic and Spinal Surgery Unit at Great Ormond Street Hospital acts as a tertiary referral centre for unusual or difficult elective paediatric orthopaedic conditions.

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Sagittal craniectomy with barrel staving

The sagittal craniectomy with barrel staving operation is used to correct an abnormal head shape. It also enlarges the space within the skull to allow the brain to grow and develop. This page from Great Ormond Street Hospital (GOSH) explains about the operation sagittal craniectomy with barrel staving, and how to prepare your child for surgery as well as what to expect in hospital afterwards.

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Spring-assisted cranioplasty

Spring-assisted cranioplasty is a type of operation used to correct the abnormal head shape seen in children with sagittal craniosynostosis. It involves removing a tiny piece of skull bone, making cuts (osteotomies) either side of the fused sagittal suture and inserting metal springs that gradually widen the gap, which encourages new bone to grow in between the two cut surfaces. It also enlarges the space within the skull to allow the brain to grow and develop. This page from Great Ormond Street Hospital (GOSH) explains about the spring-assisted cranioplasty operation, which is used to treat craniofacial disorders. It explains how to prepare your child for surgery as well as what to expect in hospital afterwards.

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Craniofacial admission criteria

This is a list of patient diagnoses which are admitted to Great Ormond Street Hospital (GOSH) by our Craniofacial team, the timeframe in which they should be treated and their estimated length of stay (LoS).

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Our services

A centre of excellence

Great Ormond Street Hospital is a specialised hospital equipped with advanced diagnostic and treatment facilities.

Our doctors, nurses and other professionals are uniquely qualified and trained to treat unusual disorders that do not respond to treatment...

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Conditions treated by the Ophthalmology department

The Ophthalmology department offers the full scope of services for paediatric patients with ophthalmological conditions.

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Infection, Cancer and Immunity (ICI)

Infection, Cancer and Immunity (ICI) is a division within Great Ormond Street Hospital (GOSH). The division covers the treatment of children with cancer, underlying immunology problems and congenital or acquired infectious diseases. Many of these children will undergo a bone marrow transplant as part of their treatment.

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Coronavirus (COVID-19)

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A centre of excellence

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