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Osteogenesis imperfecta 

Osteogenesis Imperfecta (OI) is a genetic condition present from birth. Its primary feature is fractures usually caused by minimal impact. This information sheet from Great Ormond Street Hospital (GOSH) describes osteogenesis imperfecta (OI), what causes it and how it can be managed. It also tells you about the highly specialised service for OI based at GOSH.

Headache

Headaches affect people of all ages – many adults remember having headaches as children. Headache in children can occur on its own (primary disorder) or as a result of another condition.

Paul O'Grady's Little Heroes: Episode five

Paul meets brothers Freddie (4) and Arthur (2), who are both being treated at Great Ormond Street Hospital (GOSH) for unrelated cancers – Arthur was diagnosed with a brain tumour and three months later, Freddie was diagnosed with sarcoma, a soft tissue cancer.

Paul also catches up with George (15), was born with two small holes in his heart and a thickness in his heart muscles. George’s condition is very rare in children, with only a few hundred people in the UK developing the condition in childhood.

Finally, we meet Angel (4), who was just three months old when doctors in Peterborough discovered she had tumours in both her kidneys. When chemotherapy was unsuccessful, she had to have both kidneys removed at GOSH and is now waiting for a transplant.

Genetic aspects of primary immunodeficiency

This booklet has been produced jointly between PID UK, Great Ormond Street Hospital (GOSH) and the Great North Children’s Hospital. It is designed to help answer the questions that families may have about the genetic aspects of primary immunodeficiencies (PID). The information has been reviewed by the PID UK Medical Advisory Panel and Patient Representative Panel and by families affected by PID but should not replace advice from a clinical immunologist or a geneticist.

Severe combined immunodeficiency (SCID)

This booklet has been produced jointly between PID UK, Great Ormond Street Hospital (GOSH) and the Great North Children’s Hospital. The information has been reviewed by the PID UK Medical Advisory Panel and Patient Representative Panel and by families affected by PID. It is designed to help answer the questions families may have about the immune condition called severe combined immunodeficiency (SCID) but should not replace advice from a clinical immunologist.

Multiple sclerosis and fatigue

Fatigue is an overwhelming sense of tiredness and exhaustion, and is a very common symptom in MS, with most people with MS experiencing fatigue in some way at some time. This information sheet from Great Ormond Street Hospital (GOSH) explains about
the fatigue that is a common feature of multiple sclerosis (MS). As well as describing what we know about fatigue, it also gives some suggestions to manage it.

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