Research and Innovation

Carrying out research into the best way to fight children’s illnesses has been one of our three main ambitions ever since our hospital opened in 1852.

We’ve come a long way since then and, with our research partner the UCL Great Ormond Street Institute of Child Health (ICH), we now form the largest paediatric centre in Europe dedicated to both clinical and basic scientific research.

Read our latest stories - and find out about our research opportunities.

We are committed to carrying out pioneering research to find treatments and cures for some of the most complex illnesses, for the benefit of children here in the UK and worldwide.

Great Ormond Street Hospital (GOSH) and UCL Great Ormond Street Institute of Child Health (ICH) were awarded NIHR Biomedical Research Centre (BRC) status in 2007, and had the award renewed in 2011. This was in recognition of the research conducted in the organisation. We are the only paediatric BRC in the UK.

Discover more about research and innovation at GOSH and the ICH.

Read our latest patient stories and find out about our research opportunities.

Find out more about the research infrastructure and facilities we have available.

Information for commercial and academic partners about how to work with us.

Learn more about the support and resources available to researchers. 

Research news

Learn about the latest research and innovation at Great Ormond Street Hospital.

Novel therapy for Battens Disease available on the NHS

Patients at Great Ormond Street Hospital (GOSH) and across England are set to receive treatment for the rare nervous system condition Battens Disease, following a deal between the NHS and manufacturer Biomarin. The drug, which is called cerliponase alfa or Brineura, has been approved by the NHS following successful clinical trials at GOSH in collaboration with other centres from across the world. 

How 3d modelling and virtual reality can benefit patients and staff ahead of surgery

​Joe, aged 15, who features on Paul O’Grady’s Little Heroes, is being treated at GOSH for Marfan Syndrome, a genetic disorder that affects the body’s connective tissue, which plays an important role in helping the body grow and develop properly. Joe has an associated heart condition and required surgery to replace his aorta, the body’s main artery. 

The medical and research team involved in his care share how they have used pioneering 3D Heart Modelling and Virtual Reality to aid understanding of his heart condition ahead of surgery.