Somers Clinical Research Facility

The Somers Clinical Research Facility plays a central role in delivering a growing volume of translational experimental medicine research within the Trust. 

The Somers Clinical Research Facility (CRF) supports this research through the provision of child friendly day-care accommodation and expert support for research into childhood diseases.

The expert CRF team works closely with dedicated support staff to provide a tailored service to investigators undertaking all types of clinical research within GOSH. There are currently over 80 active clinical studies being conducted within the CRF.

The CRF opened at GOSH in December 2008 and is central to our delivery of high impact clinical studies. Generous support towards the capital costs for this development was given by Dame Somers and the JN Somers Charitable Wills Trust and Friends of Great Ormond Street Hospital (GOSH).

Another key aim of the CRF is to provide a management and career development structure for all children’s research nurses working within GOSH/ICH. The CRF Children’s Research Nursing team works in concert with other clinical research staff supported by the NIHR Local Comprehensive Research Network, including nurses and data managers, who are also based in the CRF.

The Somers CRF is the central point of contact for commercial partners looking to undertake clinical trials at GOSH. Over 40% of the studies hosted by the CRF are commercially sponsored.

Recent successes include the Summit plc trial, to which the first two global patients were recruited in the CRF. The CRF has supported a BioMarin Pharmaceuticals sponsored clinical trial that has led to the clinical development and approval of a drug called VIMIZIM as a treatment for Morquio A syndrome. These successes demonstrate the importance of support for the CRF in continuing to deliver high quality and complex clinical studies for paediatric and rare diseases.

Please visit the CRF pages on the Research and Innovation pages of Great Ormond Street Hospital website to learn more about: