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Biomedical Research Centre news

New technique to aid diagnosis of glycosylation disorders present at birth

28 Jun 2016, 2:21 p.m.

A study, supported by the NIHR Great Ormond Street BRC, investigated the use of a 2D-differential gel electrophoresis (DIGE) method that provides a global analysis of the serum glycoproteome (glycomic profiling). 2D-DIGE allows multiple samples to be run

Trial suggests no adverse effects of vaginal progesterone prophylaxis for the prevention of preterm birth on child at age two

28 Jun 2016, 2:18 p.m.

Diagnostics and Imaging Theme Lead Professor Neil Sebire has teamed up with researchers from nine other establishments to carry out the largest randomised trial to investigate the long-term safety of vaginal progesterone prophylaxis for preterm births.

Phase I clinical trial utilising CAR T cells to treat refractory neuroblastoma has opened at GOSH

28 Jun 2016, 2:15 p.m.

A Phase I clinical trial of T-cell immunotherapy for relapsed or refractory neuroblastoma has opened at Great Ormond Street Hospital (GOSH).

Clinical trial to investigate treatment of acute lymphoblastic leukaemia to open at GOSH

28 Jun 2016, 2:12 p.m.

A Phase I clinical trial (CARPALL) has opened at Great Ormond Street Hospital (GOSH) to investigate the use of immunotherapy with genetically modified T cells for acute lymphoblastic leukemia (ALL). The trial is led by Professor Persis Amrolia, who is sup

Reduced risk of pulmonary embolism in children treated with long term parenteral nutrition

28 Jun 2016, 2:08 p.m.

Researchers at Great Ormond Street Hospital (GOSH) have shown a reduction in the incidence of pulmonary embolism in patients receiving parenteral nutrition after the introduction of a new mixed intravenous lipid emulsion.