Medicines information

The information in this section describes medicines, how they are given and some of their possible side effects.

If you have any questions or concerns about medications, please ask your doctor, nurse or pharmacist.

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Search for information on medicines at Great Ormond Street Hospital.


Procarbazine is a chemotherapy medicine used to treat cancer, such as Hodgkin’s Disease, a cancer of the lymph glands. It is occasionally used to treat liver and brain tumours.


Rasburicase is a medicine that is sometimes given at the start of chemotherapy for leukaemia or lymphomas. When chemotherapy starts to kill the leukaemia or lymphoma cells, uric acid is released from inside these cells. It can crystallise and cause damage to the kidneys. Rasburicase works by allowing uric acid to be more easily removed from the body by the kidneys.

Taking antibiotics as prevention

Antibiotics are the most common kind of medicine prescribed in the UK. They are a group of medicines that act against bacteria. Different types of antibiotics work in different ways, but they either kill off the bacteria or stop them growing and multiplying. They are mainly prescribed for a short ‘course’ to treat bacterial infections, often throat, chest or urine infections. Antibiotics can also be taken to prevent a bacterial infection developing.


Temozolomide is a chemotherapy drug used to treat certain types of cancer. This page from Great Ormond Street Hospital (GOSH) explains what temozolomide is, how it is given and some of the possible side effects.


Spironolactone belongs to a group of medicines called diuretics. It is commonly used alongside another medicine called furosemide to reduce fluid overload, so reducing the amount of work the heart has to do to pump blood around the body.