Septo-optic dysplasia is the name given to the condition where a child is diagnosed with two or more of the following problems: optic nerve hypoplasia, midline brain abnormalities and pituitary gland abnormalities. It is a rare condition affecting around 1 in every 10,000 births, with boys and girls affected equally.
Anal fissures are tiny tears in the skin around the anus and can be painful. They usually develop as a side effect of constipation. Constipation is the condition where a person passes faeces (poo) less frequently than usual and the poo is harder, drier and painful to pass.
Cutis aplasia means ‘missing skin’ and is a congenital (present at birth) condition where a section of skin, usually on the scalp, is missing. This page explains the condition called cutis aplasia, what causes it and how it can be treated. It also outlines what you can expect when a child comes to Great Ormond Street Hospital (GOSH) for assessment and treatment.
Cutaneous mastocytosis is a condition characterised by increased numbers of mast cells in the skin. Mast cells are part of the immune system.This page from Great Ormond Street Hospital (GOSH) explains the causes, symptoms and treatment of cutaneous mastocytosis and where to get help.
Neuronal migration disorder is an umbrella term given to several conditions including lissencephaly, agenesis of the corpus callosum and microgyria. They all arise while the baby is developing in the womb.This information sheet from Great Ormond Street Hospital (GOSH) explains the causes, symptoms and treatment of neuronal migration disorders and where to get help.
Periventricular leukomalacia (PVL) is a type of brain injury that is most common in babies born too soon (premature) or at low birthweight. The white matter (leuko) surrounding the ventricles of the brain (periventricular) is deprived of blood and oxygen leading to softening (malacia). The white matter is responsible for transmitting messages from nerve cells in the brain so damage to the white matter can cause problems with movement and other body functions.