Conditions we treat

Use the search box below to learn more about the conditions we treat at Great Ormond Street Hospital. 

Aortic valve stenosis

The aortic valve is a one-way valve between the left pumping chamber (ventricle) of the heart and the major blood vessel taking blood to the body (aorta). Aortic stenosis (AS) describes a condition where the aortic valve is smaller or tighter than it should be.

Aortic regurgitation

Aortic regurgitation occurs when the aortic valve (linking the left ventricle to the aorta) does not close properly when the heart contracts. This means blood leaks back into the left ventricle, which then has to work harder to pump the extra blood away from the heart to the rest of the body. This can lead to the enlargement and thickening of the ventricle wall.