Infantile neuroaxonal dystrophy (INAD) is a rare inherited disorder affecting the nerve axons (which are responsible for conducting messages) in the brain and other parts of the body, causing a progressive loss of vision and of physical and mental skills.
Megalencephalic leukoencephalopathy with subcortical cysts (MLC1) is a very rare disorder affecting the ‘white matter’ of the brain, often leading to progressive loss of physical, and sometimes mental, skills over very many years.
This page from Great Ormond Street Hospital (GOSH) explains the neurological condition Vein of Galen Malformation (VGM). It aims to help understanding the condition, how it can be treated and what to expect when a child is admitted to GOSH.
Myelomeningocele is a type of spina bifida. This is when the neural tube has failed to close and the neural tissue is exposed on the baby’s back. The myelomeningocele will look like a sac sticking out from a baby’s back.
Optic neuritis (ON) is an attack of inflammation (swelling) of the optic nerve. The optic nerve is important in sending information from the eye to the brain about what we are seeing. ON is caused by the body’s immune system becoming mis-programmed and activating immune cells to attack the healthy myelin covering the optic nerve.
A cleft is a hole or gap affecting the tissues in the lip. This information sheet from Great Ormond Street Hospital (GOSH) explains the causes, symptoms and treatment of cleft lip and where to get help.
A cleft lip is a gap in the upper lip and can involve the gum as well. It can affect one side (unilateral) or both sides (bilateral) of the upper lip. It can be a small gap in the lip (incomplete cleft lip) or it can extend into the base of the nose (complete cleft lip).
Syndactyly means 'joined digits' and may involve webbing of the skin, or include fusion of the underlying bones. This may be along part or the whole length of the finger. It is the second most common congenital hand problem and occurs in around 1 in 1,000 births.