Conditions we treat

Want to know more about the conditions we treat at Great Ormond Street Hospital (GOSH)? Just search below:

Henoch Schönlein Purpura (HSP)

Henoch Schönlein purpura (HSP) is a disease where small blood vessels called capillaries become inflamed and damaged, producing a rash on the skin called ’purpura’. This information sheet from Great Ormond Street Hospital (GOSH) explains about Henoch Schönlein purpura (HSP), what causes it and how it can be treated. It also gives details of what to expect when your child has assessment and treatment.

Acute disseminated encephalomyelitis (ADEM)

Acute disseminated encephalomyelitis (ADEM) is a rare inflammatory condition that affects the brain and spinal cord. It often follows on from a minor infection such as a cold, and is the result of the immune system becoming mis-programmed, and activating immune cells to attack the healthy myelin (a fatty protective coating) covering the nerves. This information sheet from Great Ormond Street Hospital (GOSH) describes the symptoms, causes and treatment of ADEM.

Opsoclonus Myoclonus Syndrome/Dancing Eye syndrome (OMS/DES)

Opsoclonus-myoclonus syndrome (OMS), also known as dancing eye syndrome (DES), is a rare neurological condition which develops over days or weeks in early childhood. This page from Great Ormond Street Hospital (GOSH) explains the causes, symptoms and treatment of Opsoclonus Myoclonus Syndrome/ Dancing Eye syndrome (OMS/DES) – also known as Kinsbourne syndrome.

Factor VII deficiency

Factor VII deficiency (also known as Alexander’s disease) is a type of clotting disorder. A specific protein is missing from the blood so that injured blood vessels cannot heal in the usual way. This information sheet from Great Ormond Street Hospital (GOSH) explains the causes, symptoms and treatment of Factor VII deficiency and where to get help.


Adrenoleukodystrophy (ALD) is a rare inherited disorder treated at Great Ormond Street Hospital (GOSH) affecting the adrenal glands and ‘white matter’ of the brain, causing a progressive loss of physical and mental skills.

Radial club hand

Radial club hand is a congenital (present at birth) hand anomaly where the radius bone in the arm is missing or underdeveloped, causing the hand to be bent towards the body (radially deviated). It is also known as radial ray deficiency or anomaly. One in 75,000 children is born with radial club hand.This page explains about radial club hand, what causes it, how common it is, what functional problems your child might have and how it can be treated.
It also explains what to expect when your child comes to Great Ormond Street Hospital (GOSH) for assessment and treatment.

Obstructive sleep apnoea

Obstructive sleep apnoea is a condition that affects the airway and how we breathe. It is called OSA because Obstructive = there is obstruction of the airway in the nose, throat or upper airway, sleep = it happens when your child is asleep and apnoea = this is a Greek word that means ‘suspension of breathing’ – there is not enough air entering the lungs. This page from Great Ormond Street Hospital (GOSH) explains the causes, symptoms and treatment of obstructive sleep apnoea (OSA).