Renal tubular markers: N-acetylglucosaminidase (NAG)




Chemical Pathology - Routine Laboratory

Clinical indications

The measurement of urinary N-Acetyl-β-D-glucosaminidase [NAG] serves as an early indicator of the presence of renal tubular damage, thus providing a means to avoid the serious consequences of untreated disease. In addition, the assay has considerable potential in the monitoring of renal involvement in some major disorders including diabetes, hypertension, urogenital tract infections and rheumatoid arthritis. Elevations in urinary NAG activity also provide a sensitive indicator of drug nephrotoxicity

Specimen requirement

1ml fresh random urine

Dispatch and handling instructions

Send by 1st class post

Turnaround time

1 to 3 weeks


Not applicable

Is it IS0 15189 accredited?