Press release courtesy of the Wellcome Trust: A gene previously linked to too much growth in patients has now also been linked to growth restriction. Different forms of the gene can lead to very different conditions, according to research published today in the journal Nature Genetics.
Oesophageal atresia (OA) is a rare condition where a short section at the top of the oesophagus (gullet or foodpipe) has not formed properly so is not connected to the stomach. This means food cannot pass from the throat to the stomach. Tracheo-oesophageal fistula (TOF) is another rare condition, which tends to occur alongside oesophageal atresia. This is where part of the oesophagus is joined to the trachea (windpipe).
A gastrostomy is a feeding tube that is inserted directly into the stomach either surgically under direct vision (open or laproscopic), endoscopically (with a camera), or radiologically (x-ray guidance). A gastrostomy tube allows the delivery of supplemental nutrition and medications directly into the stomach. It also provides a mechanism to drain gastric contents if required. In order for gastrostomy feeding to be successful the child or young person must have a functioning gastrointestinal tract.
The symptoms of a 15-year-old girl with a rare disorder improved dramatically after just one day of treatment with the B vitamins biotin and thiamine administered by Great Ormond Street Hospital (GOSH).
An adrenaline provocation test is carried out to diagnose two conditions. One called Long QT syndrome the other CPVT (Catecholeminergic Polymorphic Ventricular Tachycardia). This information sheet explains about adrenaline provocation tests, what is involved and what to expect when your child comes to Great Ormond Street Hospital (GOSH) for the test.
This page from Great Ormond StreetHospital (GOSH) explains about the different forms of supraventricular tachycardia – AV node re-entry tachycardia, atrial flutter, AV reciprocating tachycardia, atrial tachycardia and junctional tachycardia – their causes, symptoms and treatment and where to get help.
The purpose of this guideline is to provide guidance in the use of arterial lines at Great Ormond Street Hospital (GOSH).
NOTE: We review our guidelines regularly and this guideline is now past its review date. The content of the guideline below may not reflect the most recent evidence based practice. Please use with caution.
Inappropriate sinus tachycardia (IST) is a condition that causes an abnormally high resting heart rate. This information sheet from Great Ormond Street Hospital (GOSH) explains the causes, symptoms and treatment of inappropriate sinus tachycardia and where to get help.
Arrhythmias are abnormal heart rhythms, which can prevent the heart pumping efficiently. This page from Great Ormond Street Hospital (GOSH) explains how the heart beats normally, what happens when it starts to beat abnormally and how it can be treated.
Earlier this summer, Young People’s Forum (YPF) member, Annabel, interviewed Mrs Lucy Jenkins, Director of the Regional Genetics Laboratory based at Great Ormond Street Hospital (GOSH). Lucy also works on the 100,000 Genomes Project, an initiative announced by David Cameron in 2012, which aims to analyse the DNA of 100,000 NHS patients.
The purpose of this document is to provide guidance for the insertion and management of Continuous Local Anaesthetic Infusion via Transversus Abdominis Plane (TAP) at Great Ormond Street Hospital (GOSH).