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Play area within the Clinical Research Facility

UKCRF Network awarded £2.4 million in public funding

19 Jan 2023, 11:28 a.m.

UK Clinical Research Facility Network awarded £2.4 million in public funding to support the delivery of early phase research studies

A group of children face away from the camera with their hands in the air, looking at a scientist in a white coat, in front of a presentation on a screen

NIHR GOSH BRC funding goes into ‘space’ to share brain research

18 Jan 2023, 9 a.m.

A theatre group funded by the NIHR GOSH Biomedical Research Centre has developed their successful children’s event into an interactive online film for schools and festivals

Artificial intelligence passes radiologists’ specialist exams, just about!

28 Dec 2022, 9 a.m.

Radiologists are specialist doctors that use scans to diagnose conditions, from broken bones to cancers. In the UK they must pass a specialist exam as part of their training. For the first time, researchers have shown that an artificial intelligence...

Alyssa on ‘cell day’ - the day she received the base-edited cell therapy. May 2022.

GOSH patient receives world-first treatment for her 'incurable' T-cell leukaemia

11 Dec 2022, 8 a.m.

In May 2022, Alyssa, 13 from Leicester, became the first reported patient in the world to receive base-edited T-cells at Great Ormond Street Hospital for Children (GOSH), in collaboration with the UCL Great Ormond Street Institute of Child Health (UCL GOS

Image of rod cells in the retina of the 'mini eyes'

'Mini eyes’ help researchers understand blindness in rare condition

18 Nov 2022, 11:48 a.m.

Researchers at UCL Great Ormond Street Institute of Child Health (UCL GOS ICH) have grown ‘mini eyes’ in the lab which will help researchers understand how blindness develops in the rare genetic condition Usher syndrome.

An artwork displayed above the main lab in the ZCR reads Together we can do so much

Celebrating three years of progress and breakthroughs at the ZCR

11 Nov 2022, 4:06 p.m.

We're celebrating three years of the Zayed Centre for Research. That's another year of breakthrough research, with hundreds of clinicians and researchers collaborating to help seriously ill children from across the globe.

A selection of images from the 2021 competition

A Moment of Discovery 2022

9 Nov 2022, 3 p.m.

The Research and Innovation Communications team at GOSH/the NIHR GOSH BRC invite you to enter our Research and Innovation Showcase: A Moment of Discovery.

A woman in a headscarf gestures towards some micro-gardens with a group of children looking on

Engaging with our neighbours on data, research and the environment

9 Nov 2022, 10:29 a.m.

One way to engage children in data, research and our environment is through the creation of micro-gardens. The GOSH scientists involved with the festival picked this activity to teach young people about the importance of natural spaces in urban areas...

A scientist holds a sample with gloved hands

Children at GOSH first to receive CRISPR-edited universal T-cells

27 Oct 2022, 9 a.m.

Researchers at GOSH and UCL GOS ICH are the first to use CRISPR/Cas9 technology to engineer donor T-cells to try to treat seriously ill children with resistant leukaemia

£35 million research boost for GOSH

14 Oct 2022, 10 a.m.

The National Institute for Health and Care Research (NIHR) has announced that the Great Ormond Street Hospital (GOSH) Biomedical Research Centre (NIHR GOSH BRC) is one of 20 centres from across the country to receive 5-years of funding.

Skye stands on the GOSH roof garden smiling while her Mum, Mairi holds her younger sister Amelia smiles and sticks her tongue out.

GOSH patient donates lung tissue for vital research

3 Oct 2022, 9:30 a.m.

Following a lung transplant in 2021, Skye donated her lung tissue to the GOSH Sample Bank in the hope that one day they will help scientists find a cure for other people living with the condition.

Europe-wide group to boost access to life-saving gene therapies

22 Sep 2022, 5 p.m.

A new Europe-wide academic group has been launched today to tackle the growing economic hurdles that are preventing new life-saving gene therapies getting to the children who need them the most.

Dr Mary Mathias sits on a park bench while Charlie perches on the arm rest and Mum stands behind them

New trial for innovative Haemophilia treatment begins at GOSH

31 Aug 2022, 9 a.m.

Researchers at Great Ormond Street Hospital (GOSH) have begun a new clinical trial for an innovative haemophilia treatment for boys under 12.

A member of GOSH staff at their computer, wearing a mask.

Our journey to build a ‘Hospital Without Walls’

4 Aug 2022, 2 p.m.

Every day, we develop innovations in care, enabling us to be one of Europe's most digitally able hospitals. Because of this strategy, we were able to use Zoom for patient video consultations just eight days after the Covid-19 pandemic began.

Sampler in a lab in the Zayed Centre for Research

Investigating the rise in hepatitis in children

25 Jul 2022, 12:15 p.m.

Due to our world-leading expertise in genomics, we've teamed up with the UK Health Security Agency (UKHSA) to understand why more children than normal are being diagnosed with liver infections (hepatitis)...

Structural imagine of the brain’s regions (left) and diffusion diagram of the wiring of a brain (right), which Lewis-Spitz Surgical Scientist Aswin Chari and his team analyse together to create a ’network’, as part of new epilepsy research which reveals how children with epilepsy have brains that are wired differently to children without the condition.

New research reveals brain wiring differences in children with epilepsy

13 Jul 2022, 2:30 p.m.

Children with epilepsy have brains that are wired differently from those without the condition, a new study by our researchers has found. This new epilepsy research paves the way for improved treatment, specifically how different surgery techniques can...

New director of UCL Great Ormond Street Institute of Child Health

30 Jun 2022, 5 p.m.

The UCL Great Ormond Street Institute of Child Health (UCL GOS ICH) has announced that Professor Helen Cross, an Honorary Consultant in Paediatric Neurology at GOSH, will take up the post of Director of the institute from 1 September 2022.

$A diagram highlighting the differences between fractures in adults and children - with fractures in children presenting in multiple different and less obvious ways$

Can we use artificial intelligence (AI) to better diagnose fractures?

10 Jun 2022, 3 p.m.

Dr Susan Shelmerdine, Consultant Paediatric Radiologist at Great Ormond Street Hospital (GOSH) discusses her research into using artificial intelligence (AI) to identify fractures in children.

People power being used to analyse eye research at GOSH

24 May 2022, 10:40 a.m.

Months of work will be completed in a few days as members of the public help to examine high-resolution images of the potentially blinding eye condition, uveitis, as part of a project working across GOSH, UCL GOS ICH and Moorfields Eye Hospital.

An illustration showing the acronym for Young People's Advisory Group (YPAG). It reads "changing research for the better" and features some colourful images of children.

What do young people want from Artificial Intelligence in healthcare?

18 May 2022, 4 p.m.

Artificial intelligence in healthcare is a rapidly growing field. Children and teenagers often have insightful questions about AI, but are rarely involved in the development of new technologies. See how we're changing this...