Infection, Cancer and Immunity (ICI) is a division within Great Ormond Street Hospital (GOSH). The division covers the treatment of children with cancer, underlying immunology problems and congenital or acquired infectious diseases. Many of these children will undergo a bone marrow transplant as part of their treatment.
Cerebrospinal fluid (CSF) is a watery liquid that surrounds the brain and spinal cord, acting as a ‘cushion’. It also supplies nutrients to the brain. Hydrocephalus occurs when either too much CSF is produced (very rare), or when it is stopped from circulating or being re-absorbed. The CSF builds up within the ventricles (cavities) of the brain resulting in increased pressure on the brain. In babies, this also causes the head to enlarge
A nasopharyngeal airway is a small, plastic tube that keeps your child’s nostrils open, allowing them to breathe more easily. This information sheet from Great Ormond Street Hospital (GOSH) explains about nasopharyngeal airways, why they might be needed for children with craniofacial conditions and how to look after them at home.
Physiotherapy is an essential part of the treatment for cystic fibrosis (CF) and should start as soon as the diagnosis of CF is confirmed. This page explains the type of physiotherapy treatment used for infants with CF at Great Ormond Street Hospital (GOSH). Further information is available online from the CF Trust website.
Factor XI deficiency (also known as Haemophilia C, plasma thromboplastin antecedent deficiency or Rosenthal syndrome) is a clotting disorder. A specific protein is missing from the blood so that injured blood vessels cannot heal in the usual way. This information sheet from Great Ormond Street Hospital (GOSH) explains the causes, symptoms and treatment of Factor XI deficiency and where to get help.
Coagulation factors are proteins, which in the blood, cause clotting. The factors are manufactured either from human blood (plasma derived) or genetic engineering (recombinant). Advice should be sought from a Consultant Haematologist prior to any decision to prescribe and administer coagulation factors.
At Great Ormond Street Hospital (GOSH), we have developed a pathway for children and young people having spinal surgery. Spinal surgery is a complex procedure, so we want you to understand the benefits and risks of the operation so you can make an informed decision about whether to go ahead. This page explains what will happen from your child’s initial clinic appointment through to discharge, which clinicians you may meet and what to expect.
Gallstones are stone-like formations found in the gallbladder. They can vary significantly in size, shape and consistency, and they can be present without causing any problems at all. This information sheet from Great Ormond Street Hospital (GOSH) explains about gallstones, what causes them and how they can be treated using an operation to remove the gall bladder (laparoscopic cholecystectomy).
Urinary retention occurs when someone cannot empty their bladder completely. Instead of all the urine being passed out through the urethra, some remains in the bladder. This page from Great Ormond Street Hospital (GOSH) explains the causes, symptoms and treatment of urinary retention and where to get help.
This guideline is intended to guide and facilitate the care of patients under the care of the clinical teams at Great Ormond Street Hospital for Children NHS Trust (GOSH). The guidance contained herein is not intended to replace individual assessment and personalised treatment of the patient.
A difference in the length of the arms or legs can occur for a number of reasons. Usually the shorter limb is abnormal, but this is not always the case, as sometimes the longer limb is the abnormal one.
This guideline is to provide guidance on the administration of oxygen therapy in a non-emergency situation at Great Ormond Street Hospital (GOSH).
NOTE: We review our guidelines regularly and this guideline is now past its review date. The content of the guideline below may not reflect the most recent evidence based practice. Please use with caution.