This guideline is intended to guide and facilitate the care of patients under the care of the clinical teams at Great Ormond Street Hospital for Children NHS Trust (GOSH). The guidance contained herein is not intended to replace individual assessment and personalised treatment of the patient.
Landau Kleffner syndrome (LKS) is a rare epilepsy. It occurs in children usually between the ages of three and nine years and is characterised by loss of language skills and silent electrical seizures during sleep. It may be associated with convulsive seizures and additional difficulties with behaviour, social interaction, motor skills and learning. It is not usually life-threatening, but can impact greatly on quality of life unless it responds well to treatment. It occurs in approximately one child in a million. The disease is more common in boys and does not usually run in families.
The aim of the epilepsy surgery is to remove the underlying cause of the seizures and therefore cure the epilepsy. In some cases, however, it may only be possible to reduce the frequency of seizures as the cause cannot totally be removed.