Meet the team who run the NIHR Great Ormond Street Hospital BRC.
Thomas Voit – Director
Professor Thomas Voit is Director of the NIHR Great Ormond Street Hospital (GOSH) BRC, Professor and Honorary Consultant of Paediatrics at GOSH, and Vice-Dean for Enterprise at UCL’s Faculty of Population Health Sciences. Thomas is a leader in translational medicine with a focus on genetics, gene therapy and neuromuscular diseases. Read more.
Lucy Wedderburn – Deputy Director and Rare Disease Cohorts Theme Lead
Lucy Wedderburn is Professor in Paediatric Rheumatology at ICH, Director of Arthritis Research UK Centre for Adolescent Rheumatology at UCL GOSH and UCL Hospitals, and GOSH/UCL Hospitals consultant. Her research interests are T cell immunology, immune regulation and muscle biology, with a major focus upon human T cell responses and immune regulation.
Laura Turner – Deputy Director of Operations, NIHR GOSH Biomedical Research Centre
Dr Laura Turner is Deputy Director of Operations at the NIHR GOSH Biomedical Research Centre. Laura has a wide range of experience of basic and translational research and operational management across multiple sectors including academia, charity, industry and the NHS. Prior to joining GOSH, Laura was the Research Manager for the Precision Medicine division of the NIHR Guy’s and St Thomas’ BRC.
Rosalind Smyth - Director UCL Great Ormond Street Institute of Child Health
Professor Rosalind Smyth is Director of the UCL Great Ormond Street Institute of Child Health (ICH), Honorary Consultant Respiratory Paediatrician at GOSH and Non-Executive Director of GOSH NHS Foundation Trust. Her research interests include clinical studies of viral/host interactions in RSV bronchiolitis, clinical trials and systematic reviews of treatments for childhood respiratory disease.
Adrian Thrasher – Gene, Stem and Cellular Therapies Theme Lead
Professor Adrian Thrasher is Lead for the Gene, Stem and Cellular Therapies theme. Adrian is Head of the Infection, Immunity, Inflammation and Physiological Medicine Programme at ICH, and Honorary Consultant Immunologist at GOSH. Adrian has also been awarded a Wellcome Trust Principal Research Fellowship. His research interests concentrate on the restoration of function in immunodeficiency diseases.
Waseem Qasim - Gene, Stem and Cellular Therapies Deputy Theme Lead
Jane Sowden - Advanced Treatments for Structural Malformations and Tissue Damage
Paolo De Coppi- Advanced Treatments for Structural Malformation and Tissue Damage Deputy Theme Lead
Lyn Chitty - Genomics and Systems Medicine Theme Lead
Professor Lyn Chitty is Deputy Director of the NIHR Great Ormond Street Hospital BRC. Professor Lyn Chitty is Professor of Genetics and Fetal Medicine at Great Ormond Street Hospital NHS Foundation Trust, NIHR Senior Investigator and Clinical Director of the North Thames Genomic Medicine Centre. Lyn’s research interest include non-invasive prenatal diagnosis, screening for fetal abnormalities and implementation of sequencing for prenatal diagnosis.
Sergi Castellano - Genomics and Systems Medicine Deputy Theme Lead
Francesco Muntoni – Novel Therapies for Translation in Childhood Diseases Theme Lead
Professor Francesco Muntoni is the lead for the Novel Therapies for Translation in Childhood Diseases Theme. Francesco is a Clinical Paediatric Neurologist with an interest in molecular aspects of neuromuscular disorders. He is the head of the Dubowitz Neuromuscular Centre at GOSH, a leading clinical and research centre specialising in paediatric neuromuscular disorders. Francesco is also chair of the ICH Developmental Neurosciences Programme. Read more.
Paul Gissen - Novel Therapies for Translation in Childhood Diseases Deputy Theme Lead
Ruth Gilbert - Rare Diesease Cohorts Deputy Theme Lead
Professor Ruth Gilbert is Professor of Clinical Epidemiology at the UCL Great Ormond Street Institute of Child Health
Darren Hargrave - Rare Disease Cohorts Deputy Theme Lead
Christopher O'Callaghan - Translational Research & Enterprise Accelerator Theme Lead
Despina Eleftheriou - Experimental Medicine Academy Deputy Theme Lead
Karin Straathof – Junior Faculty clinical lead
Haiyan Zhou - Junior Faculty non-clinical lead
Dr Haiyan Zhou is a principal investigator and lecturer in genetics and genomic medicine and non-clinical lead for the NIHR GOSH BRC Junior Faculty. Her research focuses on RNA-targeted therapy in genetic conditions and translational biomedical research in muscular dystrophies.
William Van’t Hoff – Director of NIHR GOSH Clinical Research Facility and CRF High-end Inpatient trials Theme Lead
Dr William Van’t Hoff is Director of the NIHR GOSH Clinical Research Facility (CRF), which is part supported through the NIHR GOSH BRC. The CRF provides specialist day care accommodation for children and young people taking part in clinical research studies. William is a Consultant Paediatric Nephrologist at GOSH and Clinical Director for NHS Engagement. His research interests include children’s renal tubular, metabolic and kidney stone disorders.
Helen Cross - CRF High-end Inpatient trials Deputy Theme Lead
Dr Jenny Rivers
Jenny is the Deputy Director of Research and Innovation at GOSH, overseeing the wide range of research taking place across the Trust. Jenny joined GOSH in November 2018 from the Royal Brompton and Harefield NHS Foundation Trust where she was Associate Director of Research, having previous experience of research management within higher education.