In this theme we invest in translational platforms including stem cell bioengineering and an induced pluripotent stem cell (iPSC) core platform to build capacity in regenerative medicine and to initiate first-in-child UK trials. We aim to pioneer advanced technologies, such as regenerative medicine and the development of new surgical devices, to provide treatment options for children with serious malformations and tissue damage
Supported by the Great Ormond Street Hospital (GOSH) Biomedical Research Centre, these Pump Prime grants provide an opportunity for researchers, academics and clinicians across a range of disciplines interested in translational research in paediatric rare diseases, to be able to undertake proof-of-principle studies to facilitate the award of further funding. ATSMTD have held; two internal pump priming rounds (2017/18 and 2019/20), funding two PhD studentships, IPSC calls that supported the production of iPSC lines for use in research that aim to develop paediatric advanced therapies and three round of the Knowledge Transfer Programme which support post-doctoral early career scientists undertake a placement at an external laboratory.
All of these funding opportunities are being held within this current BRC 5 year cycle (2017-2022) , awarding a total of 4 pump prime projects (>£150k total). 15 IPSC lines projects, 7 Knowledge Transfers and 2 PhD studentships. You can view the lay summaries/reports of the projects and their impacts by expanding the blue drop down menus below.